Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On August 4, 2020, Kevin Tang provided notice to Heron Therapeutics, Inc. (the "Company") that, in order to allow him to dedicate more time to his other endeavors, he intended to resign from the Board of Directors (the "Board") of the Company and as its Chairman, effective immediately. Mr. Tang had served as a member of the Compensation Committee and the Nominating and Corporate Governance Committee of the Board. In order to maintain the appropriate proportion of independent directors on the Board, on August 4, 2020, John Poyhonen resigned from the Board, effective immediately. Mr. Poyhonen will continue to serve as Executive Vice President and Chief Commercial Officer of the Company. The decisions by Messrs. Tang and Poyhonen to resign from the Board were not the result of any disagreement with the Company on any matter relating to the Company's operations, policies or practices.

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