This Quarterly Report on Form 10-Q contains statements which, to the extent they
are not statements of historical fact, constitute "forward-looking statements."
Such forward-looking statements about our business and expectations within the
meaning of the Private Securities Litigation Reform Act of 1995, Section 27A of
the Securities Act of 1933, as amended, and Section 21E of the Securities
Exchange Act of 1934, as amended (the "Exchange Act"), include statements
relating to, among other things, the impact of the COVID-19 pandemic; future
revenue growth rates; projected tax rates and the impact of tax legislation and
regulatory action; business trends, earnings and other measures of financial
performance; the effect of economic downturns on our business performance;
projected impact of foreign currency exchange rates; demand for our products;
realizability of assets; future cash flow and uses of cash; future repurchases
of common stock; future levels of indebtedness, capital spending and operating
expenditures; the working capital and liquidity outlook; interest expense;
warranty expense; share-based compensation expense; the adoption and projected
impact of new accounting standards; critical accounting estimates; future
commercial efforts; and competition. Forward-looking statements can be
identified by the use of words such as "expects," "may," "anticipates,"
"intends," "would," "will," "plans," "believes," "estimates," "should,"
"project," and similar words and expressions. These forward-looking statements
are intended to provide our current expectations or forecasts of future events;
are based on current estimates, projections, beliefs, and assumptions; and are
not guarantees of future performance. Actual events or results may differ
materially from those described in the forward-looking statements. These
forward-looking statements involve a number of risks and uncertainties,
including, among other things, the adverse impact, and the duration, of the
effects of the ongoing COVID-19 pandemic on our business, results of operations,
liquidity, financial condition, and stock price, as well as the other matters
described under the headings "Business," "Risk Factors," "Legal Proceedings,"
"Management's Discussion and Analysis of Financial Condition and Results of
Operations," and "Quantitative and Qualitative Disclosure About Market Risk" in
our 2020 Annual Report and in the corresponding sections of this Quarterly
Report on Form 10-Q, as well as those described from time to time in our other
periodic reports filed with the SEC.

Any forward-looking statements represent our estimates only as of the day this
Quarterly Report on Form 10-Q was filed with the SEC and should not be relied
upon as representing our estimates as of any subsequent date. From time to time,
oral or written forward-looking statements may also be included in other
materials released to the public. While we may elect to update forward-looking
statements at some point in the future, we specifically disclaim any obligation
to do so, even if our estimates or expectations change.

You should read the following discussion and analysis in conjunction with our
2020 Annual Report that includes additional information about us, our results of
operations, our financial position, and our cash flows, and with our unaudited
condensed consolidated financial statements and related notes included in Part
I. Item 1. of this Quarterly Report on Form 10-Q.

Our fiscal quarter ended on March 31. Unless otherwise stated, the analysis and
discussion of our financial condition and results of operations below, including
references to growth and organic growth and increases and decreases, are being
compared to the equivalent prior-year periods.

Business Overview



We develop, manufacture, and distribute products and provide services primarily
for the companion animal veterinary, livestock, poultry and dairy, and water
testing markets. We also design, manufacture, and distribute point of care and
laboratory diagnostics for the human medical diagnostics market. Our primary
products and services are:

•Point-of-care veterinary diagnostic products, comprising instruments,
consumables, and rapid assay test kits;
•Veterinary reference laboratory diagnostic and consulting services;
•Practice management and diagnostic imaging systems and services used by
veterinarians;
•Health monitoring, biological materials testing, laboratory diagnostic
instruments and services used by the biomedical research community;
•Diagnostic, health-monitoring products for livestock, poultry, and dairy;
•Products that test water for certain microbiological contaminants; and
•Point-of-care electrolytes, blood gas analyzers, and SARS-CoV-2 RT-PCR
(COVID-19 test) used in the human medical diagnostics market.

Operating Segments. We operate primarily through three business segments:
diagnostic and information technology-based products and services for the
veterinary market, which we refer to as the Companion Animal Group ("CAG"),
water quality products ("Water") and diagnostic products and services for
livestock and poultry health and to ensure the quality and safety of milk and
improve dairy reproductive efficiency, which we refer to as Livestock, Poultry
and Dairy ("LPD"). Our
                                       28
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Other operating segment combines and presents products for the human medical
diagnostics market ("OPTI Medical") with our out-licensing arrangements because
they do not meet the quantitative or qualitative thresholds for reportable
segments.

CAG develops, designs, manufactures, and distributes products and performs
services for veterinarians and the biomedical analytics market, primarily
related to diagnostics and information management. Water develops, designs,
manufactures, and distributes a range of products used in the detection of
various microbiological parameters in water. LPD develops, designs,
manufactures, and distributes diagnostic tests and related software and performs
services that are used to manage the health status of livestock and poultry, to
improve bovine reproductive efficiency, and to ensure the quality and safety of
milk and food. OPTI Medical develops, designs, manufactures and distributes
point-of-care and laboratory diagnostics (including electrolyte and blood gas
analyzers and related consumable products) for the human medical diagnostics
market.

Effects of Certain Factors and Trends on Results of Operations



CAG Market Trends. Companion animal healthcare markets continued to benefit in
the first quarter from a step up in average clinical visits per week per
practice that began in the second half of 2020, supported by high new patient
growth. U.S. veterinary practices experienced strong clinical demand benefiting
from high growth in both non-wellness and wellness clinical visits. Our analysis
of companion animal practice data in the U.S. indicated same-store clinical
visit growth reached 12% in the first quarter, including 9% growth in
non-wellness visits and 16% growth in wellness visits. Clinical visits continued
to benefit from an increase in new clinical patient visits. Revenue growth at
U.S. veterinary practices was 15% in the first quarter, driven by a continued
focus on expanded healthcare services, including increases in utilization of
diagnostics.

While these CAG market and other trends are encouraging, potential effects
related to ongoing COVID-19 case management efforts are challenging to predict
and may pressure future revenues in CAG and our other segments should enhanced
social distancing policies and higher infection rates impact our customers in
certain regions.

Currency and Other Items

Currency Impact. See "Part I. Item 3. Quantitative and Qualitative Disclosures
about Market Risk" included in this Quarterly Report on Form 10-Q for additional
information regarding the impact of foreign currency exchange rates.

Other Items. See "Part I. Item 1. Business - Patents and Licenses" and "Part II.
Item 7. Management's Discussion and Analysis of Financial Condition and Results
of Operations" included in our 2020 Annual Report for additional information
regarding distributor purchasing and inventories, economic conditions, and
patent expiration.

Critical Accounting Estimates and Assumptions



The discussion and analysis of our financial condition and results of operations
is based upon our unaudited condensed consolidated financial statements, which
have been prepared in accordance with U.S. GAAP. The preparation of these
financial statements requires us to make estimates and judgments that affect the
reported amounts of assets, liabilities, revenues and expenses, and related
disclosure of contingent assets and liabilities. We evaluate our estimates on an
ongoing basis. We base our estimates on historical experience and on various
assumptions that we believe to be reasonable under the circumstances, the
results of which form the basis for making judgments about the carrying values
of assets and liabilities that are not readily apparent from other sources.
Actual results may differ from these estimates. The critical accounting policies
and the significant judgments and estimates used in the preparation of our
unaudited condensed consolidated financial statements for the three months ended
March 31, 2021, are consistent with those discussed in our 2020 Annual Report in
the section under the heading "Part II. Item 7. Management's Discussion and
Analysis of Financial Condition and Results of Operations - Critical Accounting
Estimates and Assumptions."

Recent Accounting Pronouncements



For more information regarding the impact that recent accounting standards and
amendments will have on our consolidated financial statements as described in
Note 2 to the unaudited condensed consolidated financial statements in Part I.
Item 1. of this Quarterly Report on Form 10-Q.

Non-GAAP Financial Measures



The following revenue analysis and discussion focuses on organic revenue growth,
and references in this analysis and discussion to "revenue," "revenues" or
"revenue growth" are references to "organic revenue growth." Organic revenue
growth is a non-GAAP financial measure and represents the percentage change in
revenue during the three months ended March 31,
                                       29
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2021, as compared to the same period for the prior year, net of the effect of
changes in foreign currency exchange rates, certain business acquisitions, and
divestitures. Organic revenue growth should be considered in addition to, and
not as a replacement for, or as a superior measure to, revenues reported in
accordance with U.S. GAAP, and may not be comparable to similarly titled
measures reported by other companies. Management believes that reporting organic
revenue growth provides useful information to investors by facilitating easier
comparisons of our revenue performance with prior and future periods and to the
performance of our peers.

We exclude from organic revenue growth the effect of changes in foreign currency
exchange rates because changes in foreign currency exchange rates are not
under management's control, are subject to volatility, and can obscure
underlying business trends. We calculate the impact on revenue resulting from
changes in foreign currency exchange rates by applying the difference between
the weighted average exchange rates during the current year period and
the comparable prior-year period to foreign currency denominated revenues for
the prior-year period.

We also exclude from organic revenue growth the effect of certain business
acquisitions and divestitures because the nature, size and number of these
transactions can vary dramatically from period to period, and because they
either require or generate cash as an inherent consequence of the transaction,
and therefore can also obscure underlying business and operating trends. We
exclude only acquisitions that are considered to be a business from organic
revenue growth. In a business combination, if substantially all the fair value
of the assets acquired is concentrated in a single asset or group of similar
assets, we do not consider these assets to be a business and include these
acquisitions in organic revenue growth. A typical acquisition that we do not
consider a business is a customer list asset acquisition, which does not have
all elements necessary to operate a business, such as employees or
infrastructure. We believe the efforts required to convert and retain these
acquired customers are similar in nature to our existing customer base and
therefore are included in organic revenue growth.

We also use Adjusted EBITDA, gross debt, net debt, gross debt to Adjusted EBITDA
ratio and net debt to Adjusted EBITDA ratio, in this Quarterly Report on Form
10-Q, all of which are non-GAAP financial measures that should be considered
in addition to, and not as a replacement for, financial measures presented
according to U.S. GAAP. Management believes that reporting these non-GAAP
financial measures provides supplemental analysis to help investors further
evaluate our business performance and available borrowing capacity under our
Credit Facility.

                                       30
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Results of Operations

Three Months Ended March 31, 2021, Compared to Three Months Ended March 31, 2020

Total Company. The following table presents total Company revenue by operating
segment:
                                     For the Three Months Ended March
                                                   31,
Net Revenue                                                                                         Reported Revenue       Percentage Change         Percentage Change         Organic Revenue
(dollars in thousands)                   2021                2020             Dollar Change            Growth (1)            from Currency           from Acquisitions           Growth (1)

CAG                                  $  692,767          $ 551,996          $      140,771                  25.5  %                    2.9  %                     0.1  %              22.4  %
United States                           444,410            373,275                  71,135                  19.1  %                      -                        0.1  %              19.0  %
International                           248,357            178,721                  69,636                  39.0  %                    9.6  %                     0.2  %              29.2  %

Water                                    34,040             34,149                    (109)                 (0.3  %)                   2.3  %                       -                 (2.6  %)
United States                            16,568             16,941                    (373)                 (2.2  %)                     -                          -                 (2.2  %)
International                            17,472             17,208                     264                   1.5  %                    4.6  %                       -                 (3.1  %)

LPD                                      39,270             34,154                   5,116                  15.0  %                    5.7  %                       -                  9.3  %
United States                             3,748              3,777                     (29)                 (0.8  %)                     -                          -                 (0.8  %)
International                            35,522             30,377                   5,145                  16.9  %                    6.5  %                       -                 10.5  %

Other                                    11,630              6,037                   5,593                  92.7  %                      -                          -                 92.7  %

Total Company                        $  777,707          $ 626,336          $      151,371                  24.2  %                    3.1  %                     0.1  %              21.0  %
United States                           472,638            396,783                  75,855                  19.1  %                      -                        0.1  %              19.0  %
International                           305,069            229,553                  75,516                  32.9  %                    8.6  %                     0.2  %              24.2  %

(1)Reported revenue growth and organic revenue growth may not recalculate due to rounding.



Total Company Revenue. The increase in both U.S. and international organic
revenues was driven by strong gains in CAG Diagnostic recurring revenue
reflecting a continued demand for companion animal diagnostics globally,
supported by high growth in both non-wellness and wellness clinical visits. The
growth in our LPD business was primarily due to the continued demand for swine
testing in China and the benefits from the timing of distributor shipments in
the current period, which was offset by the impact of prior year accelerated
customer stocking orders in response to the onset of the COVID-19 pandemic.
Water revenues declined primarily from the impact of prior year accelerated
customer stocking orders in response to the onset of the COVID-19 pandemic. The
impact of currency movements increased total revenue by 3.1%, while acquisitions
increased revenue by 0.1%.


                                       31

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The following table presents total Company results of operations:


                                                             For the Three Months Ended March 31,                                         Change
Total Company - Results of
Operations                                                      Percent of                              Percent of
(dollars in thousands)                        2021               Revenue               2020              Revenue              Amount             Percentage

Revenues                                  $  777,707                               $ 626,336                               $ 151,371                    24.2  %
Cost of revenue                              306,925                                 266,746                                  40,179                    15.1  %
Gross profit                                 470,782                 60.5  %         359,590                 57.4  %         111,192                    30.9  %

Operating Expenses:
Sales and marketing                          114,811                 14.8  %         116,143                 18.5  %          (1,332)                   (1.1) %
General and administrative                    70,770                  9.1  %          65,812                 10.5  %           4,958                     7.5  %
Research and development                      37,579                  4.8  %          33,310                  5.3  %           4,269                    12.8  %
Total operating expenses                     223,160                 28.7  %         215,265                 34.4  %           7,895                     3.7  %
Income from operations                    $  247,622                 31.8  %       $ 144,325                 23.0  %       $ 103,297                    71.6  %



Gross Profit. Gross profit increased due to higher sales volumes, as well as a
310 basis point increase in the gross profit margin. The increase in the gross
profit margin was primarily due to volume leverage in our reference laboratories
and high growth in IDEXX VetLab® consumables, and the net benefit of price
increases in our CAG Diagnostics recurring revenue portfolio. The impact from
foreign currency movements decreased the gross profit margin by approximately 10
basis points, including the impact of hedge gains in the current year compared
to hedge losses in the prior year.

Operating Expenses. The decrease in sales and marketing expense was primarily
due to decreases in travel, trade shows and in-person sales meetings, due to
continued travel restrictions for the COVID-19 pandemic. This decrease was
partially offset by higher project costs and increased personnel-related costs.
The increase in general and administrative expense was primarily due to higher
personnel-related costs, partially offset by an increase in the bad debt reserve
during the first quarter of 2020 and lower travel costs. The increase in
research and development expense is primarily due to higher personnel-related
and project costs. The overall change in currency exchange rates increased
operating expenses by less than 1%.

                                       32
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Companion Animal Group

The following table presents revenue by product and service category for CAG:


                             For the Three Months Ended March
                                           31,
Net Revenue                                                                                 Reported Revenue       Percentage Change         Percentage Change         Organic Revenue
(dollars in thousands)           2021                2020             Dollar Change            Growth (1)            from Currency           from Acquisitions           Growth (1)

CAG Diagnostics
recurring revenue:           $  617,280          $ 487,925          $      129,355                   26.5  %                   3.1  %                     0.1  %               23.3  %
IDEXX VetLab
consumables                     246,092            188,713                  57,379                   30.4  %                   4.0  %                       -                  26.4  %
Rapid assay products             69,611             57,430                  12,181                   21.2  %                   1.2  %                       -                  20.0  %
Reference laboratory
diagnostic and
consulting services             275,781            220,261                  55,520                   25.2  %                   2.8  %                     0.3  %               22.2  %
CAG diagnostics
services and
accessories                      25,796             21,521                   4,275                   19.9  %                   3.8  %                       -                  16.0  %
CAG Diagnostics
capital - instruments            31,190             23,833                   7,357                   30.9  %                   3.9  %                       -                  27.0  %
Veterinary software,
services and
diagnostic imaging
systems                          44,297             40,238                   4,059                   10.1  %                   0.9  %                       -                   9.2  %
Net CAG revenue              $  692,767          $ 551,996          $      140,771                   25.5  %                   2.9  %                     0.1  %               22.4  %


(1) Reported revenue growth and organic revenue growth may not recalculate due to rounding



CAG Diagnostics Recurring Revenue. We continue to see strong market demand for
companion animal diagnostics globally across modalities, including high levels
of growth in testing volumes following the initial pandemic impacts, which
constrained volumes beginning in mid-March 2020 through May 2020. This volume
growth includes higher clinical visits related to new patients and an increase
in diagnostic utilization per clinical visit. The increase in CAG Diagnostics
recurring revenue was primarily due to increased volumes in IDEXX VetLab
consumables, reference laboratory diagnostic services, and rapid assay products,
and to a lesser extent, higher realized prices.

The increase in IDEXX VetLab consumables revenue was primarily due to higher
sales volumes for our Catalyst consumables and, to a lesser extent, ProCyte Dx®
consumables. These increases were supported by an expansion of our instrument
installed base, growth in testing by new and existing customers, our expanded
menu of available tests, and to a lesser extent, benefits from higher average
unit sales prices.

The increase in rapid assay revenue resulted primarily from higher SNAP® 4Dx
Plus sales volumes, as well as higher realized prices. Rapid assay testing is
supported by high demand for wellness testing.

The increase in reference laboratory diagnostic and consulting services revenue
was primarily due to the impact of higher testing volumes globally, as well as
higher average unit sales prices.

The increase in CAG Diagnostics services and accessories revenue was primarily a result of the increase in our active installed base of instruments.

CAG Diagnostics Capital - Instruments Revenue. The increase in instrument
revenue was primarily due to strong premium instrument placements globally, as
compared to constrained placements in the first quarter of 2020, when certain
customers deferred instrument orders and placements at the onset of the
pandemic.

Veterinary Software, Services and Diagnostic Imaging Systems Revenue. The increase in revenue was primarily due to increased veterinary software and diagnostic imaging subscription-based services due to the increases in our active installed base, new veterinary software system placements, and to a lesser extent, higher realized prices on these service offerings. These favorable impacts were partially offset by a decrease in diagnostic imaging instrument revenue impacted by a reduction in earlier generation instrument platform sales.


                                       33
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The following table presents the CAG segment results of operations:


                                                                     For the Three Months Ended March 31,                                         Change
Results of Operations                                                   Percent of                              Percent of
(dollars in thousands)                                2021               Revenue               2020              Revenue              Amount             Percentage

Revenues                                          $  692,767                               $ 551,996                               $ 140,771                    25.5  %
Cost of revenue                                      279,893                                 242,653                                  37,240                    15.3  %
Gross profit                                         412,874                 59.6  %         309,343                 56.0  %         103,531                    33.5  %

Operating Expenses:
Sales and marketing                                  104,291                 15.1  %         106,002                 19.2  %          (1,711)                   (1.6) %
General and administrative                            62,904                  9.1  %          55,603                 10.1  %           7,301                    13.1  %
Research and development                              32,469                  4.7  %          29,079                  5.3  %           3,390                    11.7  %
Total operating expenses                             199,664                 28.8  %         190,684                 34.5  %           8,980                     4.7  %
Income from operations                            $  213,210                 30.8  %       $ 118,659                 21.5  %       $  94,551                    79.7  %



Gross Profit. Gross profit increased primarily due to higher sales volume, as
well a 360 basis point increase in the gross profit margin. The increase in the
gross profit margin was primarily due to volume leverage in our reference
laboratories and high growth in VetLab consumables, and the net benefit of price
increases in our CAG Diagnostics recurring revenue portfolio. These favorable
factors were partially offset by incremental investments in reference laboratory
capacity, including increased staffing and related personnel costs and systems.
The impact from foreign currency movements increased the gross profit margin by
less than 10 basis points, including the impact of hedge losses in the current
year compared to hedge gains in the prior year.

Operating Expenses. The decrease in sales and marketing expense was primarily
due to decreases in travel, trade shows, and in-person sales meetings due to
continued travel restrictions from the COVID-19 pandemic, partially offset by
higher personnel-related costs. The increase in general and administrative
expense was primarily due to higher personnel-related costs, partially offset by
an increase in the bad debt reserve during the first quarter of 2020 and lower
travel costs. The increase in research and development expense was primarily due
to increased personnel-related and project costs. The overall change in currency
exchange rates resulted in an increase in operating expenses by approximately
1%.

                                       34
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Water

The following table presents the Water segment results of operations:


                                                                    For the Three Months Ended March 31,                                       Change
Results of Operations                                                  Percent of                             Percent of
(dollars in thousands)                                2021              Revenue              2020              Revenue             Amount             Percentage

Revenues                                          $  34,040                               $ 34,149                               $   (109)                  (0.3)  %
Cost of revenue                                      10,575                                  9,400                                  1,175                   12.5  %
Gross profit                                         23,465                 68.9  %         24,749                 72.5  %         (1,284)                  (5.2)  %

Operating Expenses:
Sales and marketing                                   4,358                 12.8  %          4,374                 12.8  %            (16)                  (0.4  %)
General and administrative                            3,236                  9.5  %          3,496                 10.2  %           (260)                  (7.4)  %
Research and development                              1,099                  3.2  %            997                  2.9  %            102                   10.2   %
Total operating expenses                              8,693                 25.5  %          8,867                 26.0  %           (174)                  (2.0)  %
Income from operations                            $  14,772                 43.4  %       $ 15,882                 46.5  %       $ (1,110)                  (7.0)  %



Revenue. The decrease in revenue was primarily due to the impact of prior year
accelerated customer stocking orders in response to the onset of the COVID-19
pandemic. This impact was partially offset by price increases in our Colilert
test products and related accessories used in coliform and E. coli testing and
improvement in non-compliance testing volume that has been constrained during
the pandemic. The impact of currency movements also increased revenue by
approximately 2.3%.

Gross Profit. Gross profit decreased due to a 360 basis point decrease in the
gross profit margin, primarily due to higher distribution and freight costs and
higher product costs, as well as a 130 basis point reduction from foreign
currency movements including the impact of hedge losses in the current year
compared to hedge gains the prior year. These reductions in the gross profit
margin were partially offset by the net benefits of price increases.

Operating Expenses. Sales and marketing and research and development expenses
were relatively flat. The decrease in general and administrative expenses was
primarily due to an increase in the bad debt reserve during the first quarter of
2020. The overall change in currency exchange rates resulted in an increase in
operating expenses of approximately 1%.

                                       35
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Livestock, Poultry and Dairy

The following table presents the LPD segment results of operations:


                                                                    For the Three Months Ended March 31,                                       Change
Results of Operations                                                  Percent of                             Percent of
(dollars in thousands)                                2021              Revenue              2020              Revenue             Amount            Percentage

Revenues                                          $  39,270                               $ 34,154                               $ 5,116                   15.0  %
Cost of revenue                                      12,389                                 11,842                                   547                    4.6  %
Gross profit                                         26,881                 68.5  %         22,312                 65.3  %         4,569                   20.5   %

Operating Expenses:
Sales and marketing                                   5,538                 14.1  %          5,382                 15.8  %           156                    2.9  %
General and administrative                            4,308                 11.0  %          4,489                 13.1  %          (181)                  (4.0  %)
Research and development                              3,227                  8.2  %          2,778                  8.1  %           449                   16.2   %
Total operating expenses                             13,073                 33.3  %         12,649                 37.0  %           424                    3.4  %
Income from operations                            $  13,808                 35.2  %       $  9,663                 28.3  %       $ 4,145                   42.9   %



Revenue. Revenue increased primarily due to the continued demand for diagnostic
testing in China supported by the rebuilding of the swine herd impacted by the
African Swine Fever outbreaks, partially offset by lower realized prices and
decreased herd health screening. The benefits from the timing of distributor
shipments in the current period, offset the impact of prior year accelerated
customer stocking orders in response to the onset of the COVID-19 pandemic. The
favorable impact of foreign currency movements increased revenue by 5.7%.

Gross Profit. The increase in gross profit was primarily due to higher sales
volumes and a 320 basis point increase in the gross profit margin. The increase
in the gross profit margin is primarily due to favorable product mix and from
volume leverage, offset by lower realized prices and the impact from foreign
currency movements, which decreased gross profit margin by approximately 100
basis points, including the impact of hedge losses in the current year compared
to hedge gains in the prior year.

Operating Expenses. The increase in sales and marketing was primarily due to
higher personnel-related costs, offset by reduced travel costs. The decrease in
general and administrative expenses was primarily due to an increase in the bad
debt reserve during the first quarter of 2020, partially offset by higher
personnel-related costs. The increase in research and development expense is
primarily due to higher personnel-related costs and third-party development
costs, partially offset by leveraging LPD personnel to support our human COVID
testing products. The overall change in currency exchange rates resulted in an
increase in operating expenses of approximately 3%.

                                       36
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Other

The following table presents the Other results of operations:


                                                                    For the Three Months Ended March 31,                                       Change
Results of Operations                                                   Percent of                            Percent of
(dollars in thousands)                                2021               Revenue              2020             Revenue             Amount            Percentage

Revenues                                          $   11,630                               $ 6,037                               $ 5,593                   92.7  %
Cost of revenue                                        4,068                                 2,851                                 1,217                   42.7  %
Gross profit                                           7,562                 65.0  %         3,186                 52.8  %         4,376                  137.4  %

Operating Expenses:
Sales and marketing                                      624                  5.4  %           385                  6.4  %           239                   62.1  %
General and administrative                               322                  2.8  %         2,224                 36.8  %        (1,902)                 (85.5  %)
Research and development                                 784                  6.7  %           456                  7.6  %           328                   71.9  %
Total operating expenses                               1,730                 14.9  %         3,065                 50.8  %        (1,335)                 (43.6  %)
Income from operations                            $    5,832                 50.1  %       $   121                  2.0  %       $ 5,711                4,719.8  %



Revenue. The increase in revenue was primarily due to our OPTI COVID-19 PCR
testing products and services, which were introduced in the second quarter of
2020. The future demand for this product is difficult to project given the
uncertain nature of the COVID-19 pandemic, including the availability of
vaccines, available PCR testing capacity, and alternative suppliers, we
currently anticipate lower revenues in the second half of 2021, as compared to
the prior year. The impact of currency movements on revenue was immaterial.

Gross Profit. The increase in gross profit was primarily due to sales volumes of
our OPTI COVID-19 PCR testing products and services. The gross profit margin
increased 1,220 basis points primarily due to favorable product mix from OPTI
COVID-19 PCR testing, partially offset by higher product costs in our other OPTI
products. The overall change in currency exchange rates had an immaterial impact
on gross profit.

Operating Expenses. The increase in sales and marketing expense was primarily
due to higher personnel-related costs associated with our OPTI COVID-19 PCR
product and services. The decrease in general and administrative expense was
primarily due to lower foreign exchange losses on settlements of foreign
currency denominated transactions, as compared to the prior year, for all
operating segments, which are reported within our Other segment. The increase in
research and development cost was primarily due to higher personnel-related and
project costs associated with the OPTI COVID-19 PCR test.

Non-Operating Items



Interest Expense. Interest expense was $7.6 million for the three months ended
March 31, 2021, as compared to $7.7 million for the same period in the prior
year.

Provision for Income Taxes. Our effective income tax rate was 14.9% for the
three months ended March 31, 2021, as compared to 18.2% for the three months
ended March 31, 2020. The decrease in our effective tax rate as compared to the
same period in the prior year, was primarily driven by higher tax benefits from
share-based compensation and regional earnings mix.


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Liquidity and Capital Resources



We fund the capital needs of our business through cash on hand, funds generated
from operations, proceeds from long-term senior note financings, and amounts
available under our Credit Facility. At March 31, 2021, we had $351.2 million
of cash and cash equivalents, as compared to $383.9 million on December 31,
2020. Working capital totaled $477.1 million at March 31, 2021, as compared to
$480.0 million at December 31, 2020. Additionally, at March 31, 2021, we had
remaining borrowing availability of $998.6 million under our $1 billion Credit
Facility, with no outstanding borrowings on the Credit Facility. The general
availability of funds under our Credit Facility is reduced by $1.4 million for
outstanding letters of credit. We believe that, if necessary, we could obtain
additional borrowings to fund our growth objectives. We further believe that
current cash and cash equivalents, funds generated from operations, and
committed borrowing availability will be sufficient to fund our operations,
capital purchase requirements, and anticipated growth needs for the next twelve
months. We believe that these resources, coupled with our ability, as needed, to
obtain additional financing, will also be sufficient to fund our business as
currently conducted for the foreseeable future. We may enter into new financing
arrangements or refinance or retire existing debt in the future depending on
market conditions. Should we require more capital in the U.S. than is generated
by our operations, for example to fund significant discretionary activities, we
could elect to raise capital in the U.S. through the incurrence of debt or
equity issuances, which we may not be able to complete on favorable terms or at
all. In addition, these alternatives could result in increased interest expense
or other dilution of our earnings.

We manage our worldwide cash requirements considering available funds among all
of our subsidiaries. Our foreign cash and marketable securities are generally
available without restrictions to fund ordinary business operations outside the
U.S.
The following table presents cash, cash equivalents and marketable securities
held domestically and by our foreign subsidiaries:
Cash, cash equivalents and marketable securities                                                     December 31,
(dollars in millions)                                                         March 31, 2021             2020

U.S.                                                                         $        204.2          $    248.4
Foreign                                                                               147.0               135.5
Total                                                                        $        351.2          $    383.9

Total cash, cash equivalents and marketable securities held in U.S. dollars by our foreign subsidiaries

$ 32.3 $ 18.0

Of the $351.2 million of cash and cash equivalents held as of March 31, 2021, greater than 99% was held as bank deposits.



The following table presents additional key information concerning working
capital:
                                                                                              For the Three Months Ended
                                                                                                                                   June 30,
                                                March 31, 2021            December 31, 2020          September 30, 2020              2020               March 31, 2020

Days sales outstanding(1)                             41.8                       42.2                        41.5                     44.4                      41.5
Inventory turns(2)                                     2.0                        2.1                         1.9                      1.6                       1.9


(1)   Days sales outstanding represents the average of the accounts receivable
balances at the beginning and end of each quarter divided by revenue for that
quarter, the result of which is then multiplied by 91.25 days.
(2)   Inventory turns represent inventory-related cost of product revenue for
the 12 months preceding each quarter-end divided by the average inventory
balances at the beginning and end of each quarter.

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Sources and Uses of Cash

The following table presents cash provided (used):


                                                                      For the Three Months Ended March 31,
(in thousands)                                                  2021                  2020             Dollar Change

Net cash provided by operating activities                 $      124,422          $  27,871          $       96,551
Net cash used by investing activities                            (24,587)           (49,670)                 25,083
Net cash (used) provided by financing activities                (129,651)            16,901                (146,552)
Net effect of changes in exchange rates on cash                   (2,949)            (4,033)                  1,084
Net change in cash and cash equivalents                   $      (32,765)

$ (8,931) $ (23,834)





Operating Activities. The increase in cash provided by operating activities of
$96.6 million was driven primarily by an increase in net income. The following
table presents cash flow impacts from changes in operating assets and
liabilities:
                                                                      For the Three Months Ended March 31,
(in thousands)                                                  2021                  2020              Dollar Change

Accounts receivable                                       $      (54,735)         $  (38,062)         $      (16,673)
Inventories                                                       (7,919)            (14,434)                  6,515
Accounts payable                                                   2,460              (1,755)                  4,215
Deferred revenue                                                  (2,287)             (2,410)                    123
Other assets and liabilities                                     (57,081)            (64,881)                  7,800
Total change in cash due to changes in operating
assets and liabilities                                    $     (119,562)         $ (121,542)         $        1,980



Cash used due to changes in operating assets and liabilities during the three
months ended March 31, 2021, as compared to the same period in the prior year,
decreased by approximately $2.0 million. The change in other assets and
liabilities was due to favorable timing of payroll, as well as higher non-cash
operating expenses recorded as accrued liabilities, including annual employee
incentive programs, partially offset by higher incentive payments in 2021, as
compared to 2020. Additionally, lower inventory growth due to high demand in the
current year contributed to lower cash used as compared to the same period in
the prior year, which was impacted by the onset of the COVID-19 pandemic. These
factors were partially offset by an increase in accounts receivable related to
revenue growth compared to the same period in the prior year, which was impacted
by the onset of the COVID-19 pandemic.

We have historically experienced proportionally lower net cash flows from
operating activities during the first quarter and proportionally higher cash
flows from operating activities for the remainder of the year driven primarily
by payments related to annual employee incentive programs in the first quarter
following the year for which the bonuses were earned.

Investing Activities. Cash used by investing activities was $24.6 million for
the three months ended March 31, 2021, as compared to $49.7 million for the same
period in the prior year. The decrease in cash used by investing activities was
primarily due to the completion of our long-term major facilities projects
during 2020.

Financing Activities. Cash used by financing activities was $129.7 million for
the three months ended March 31, 2021, as compared to $16.9 million of cash
provided for the same period in the prior year. The increase in cash used by
financing activities was due to lower borrowings on our Credit Facility compared
to the first quarter of 2020, partially offset by using less cash to repurchase
shares of our common stock during the first quarter of 2021, as compared to the
same period in the prior year.

Cash used to repurchase shares of our common stock decreased $50.6 million
during the three months ended March 31, 2021. We believe that the repurchase of
our common stock is a favorable means of returning value to our stockholders,
and we also repurchase our stock to offset the dilutive effect of our
share-based compensation programs. Repurchases of our common stock may vary
depending upon the level of other investing activities and the share price. See
Note 11 to the unaudited condensed consolidated financial statements in Part I.
Item 1. of this Quarterly Report on Form 10-Q for additional information about
our share repurchases.

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There was no activity under our Credit Facility during the three months ended
March 31, 2021, as compared to $198.1 million of net borrowings in the same
period of the prior year. At March 31, 2021, we had no outstanding borrowings
under the Credit Facility. The Credit Facility contains affirmative, negative,
and financial covenants customary for financings of this type. The negative
covenants include restrictions on liens, indebtedness of subsidiaries of the
Company, fundamental changes, investments, transactions with affiliates, certain
restrictive agreements and violations of laws and regulations. The obligations
under our Credit Facility may be accelerated upon the occurrence of an event of
default under the Credit Facility, which includes customary events of default
including payment defaults, defaults in the performance of the affirmative,
negative and financial covenants, the inaccuracy of representations or
warranties, bankruptcy and insolvency-related defaults, defaults relating to
judgments, certain events related to employee pension benefit plans under the
Employee Retirement Income Security Act of 1974 ("ERISA"), the failure to pay
specified indebtedness, cross-acceleration to specified indebtedness and a
change of control default.

The Credit Agreement contains affirmative, negative, and financial covenants
customary for financings of this type. The negative covenants include
restrictions on liens, indebtedness of subsidiaries of the Company, fundamental
changes, investments, transactions with affiliates, certain restrictive
agreements and sanctions laws and regulations. The financial covenant is a
consolidated leverage ratio test.

On July 21, 2021, our 2021 Series A Notes for $50 million becomes due, and we
anticipate paying the Series A Notes with cash provided by operations. Should we
elect to prepay the senior notes, such aggregate prepayment will include the
applicable make-whole amount(s), as defined within the applicable Senior Note
Agreements. Additionally, in the event of a change in control of the Company or
upon the disposition of certain assets of the Company the proceeds of which are
not reinvested (as defined in the Senior Note Agreements), we may be required to
prepay all or a portion of the senior notes. The obligations under the senior
notes may be accelerated upon the occurrence of an event of default under the
applicable Senior Note Agreements, each of which includes customary events of
default including payment defaults, defaults in the performance of the
affirmative, negative and financial covenants, the inaccuracy of representations
or warranties, bankruptcy and insolvency-related defaults, defaults relating to
judgments, certain events related to employee pension benefit plans under ERISA,
the failure to pay specified indebtedness and cross-acceleration to specified
indebtedness.

Effect of Currency Translation on Cash. The net effect of changes in
foreign currency exchange rates is related to changes in exchange rates between
the U.S. dollar and the functional currencies of our foreign subsidiaries. These
changes will fluctuate for each period presented as the value of the U.S.
dollar relative to the value of the foreign currencies changes. A currency's
value depends on many factors, including interest rates and the country's debt
levels and strength of economy.

Off-Balance Sheet Arrangements. We have no off-balance sheet arrangements or variable interest entities, except for letters of credit and third-party guarantees.


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Financial Covenant. The sole financial covenant of our Credit Facility and
Senior Note Agreements is a consolidated leverage ratio test that requires our
ratio of debt to earnings before interest, taxes, depreciation and amortization,
non-recurring transaction expenses incurred in connection with acquisitions,
share-based compensation expense, and certain other non-cash losses and charges
("Adjusted EBITDA") not to exceed 3.5-to-1. At March 31, 2021, we were in
compliance with such covenant. The following details our consolidated leverage
ratio calculation:
(in thousands)                                            Twelve months 

ended


Trailing 12 Months Adjusted EBITDA:                          March 31, 2021

Net income attributable to stockholders (as reported)    $            674,206
Interest expense                                                       33,017
Provision for income taxes                                             90,738
Depreciation and amortization                                          97,851
Acquisition-related expense                                               773
Share-based compensation expense                                       

32,542


Extraordinary and other non-recurring non-cash charges                  2,501
Adjusted EBITDA                                          $            931,628

(in thousands)
Debt to Adjusted EBITDA Ratio:                               March 31, 2021

Line of credit                                           $                  -
Current and long-term portions of long-term debt                      

903,718


Total debt                                                            

903,718


Acquisition-related contingent consideration payable                    2,608
Financing leases                                                           22
Deferred financing costs                                                  609
Gross debt                                               $            906,957
Gross debt to Adjusted EBITDA ratio                                      

0.97



Less: Cash and cash equivalents                          $           

(351,163)


Net debt                                                 $            

555,794


Net debt to Adjusted EBITDA ratio                                        

0.60





Adjusted EBITDA, gross debt, net debt, gross debt to Adjusted EBITDA ratio and
net debt to Adjusted EBITDA ratio are non-GAAP financial measures which
should be considered in addition to, and not as a replacement for, financial
measures presented according to U.S. GAAP. Management believes that reporting
these non-GAAP financial measures provides supplemental analysis to help
investors further evaluate our business performance and available borrowing
capacity under our Credit Facility.

Other Commitments, Contingencies and Guarantees

Significant commitments, contingencies and guarantees at March 31, 2021, are described in Note 15 to the unaudited condensed consolidated financial statements in Part I. Item 1. of this Quarterly Report on Form 10-Q.


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