NEW YORK, June 14, 2013 /PRNewswire/ --
Today, Wall Street Reports announced new research reports highlighting Alexion
Pharmaceuticals, Inc. (NASDAQ: ALXN), BioMarin Pharmaceutical Inc. (NASDAQ: BMRN), Onyx
Pharmaceuticals, Inc. (NASDAQ: ONXX), Questcor Pharmaceuticals, Inc. (NASDAQ: QCOR), and
ImmunoGen, Inc. (NASDAQ: IMGN). Today's readers may access these reports free of charge -
including full price targets, industry analysis and analyst ratings - via the links below.
Alexion Pharmaceuticals, Inc. Research Report
On June 5, 2013, Alexion Pharmaceuticals, Inc. (Alexion) announced that the results of
trials published in The New England Journal of Medicine (NEJM) showed that chronic Soliris
(eculizumab) therapy is effective in the treatment of patients with atypical hemolytic
uremic syndrome (aHUS), a genetic, life-long, ultra-rare disease associated with vital
organ failure and premature death. According to results of two pivotal studies published
in the NEJM, chronic Soliris treatment substantially inhibits systemic complement-mediated
thrombotic microangiopathy (TMA), decreases the need for TMA-related intervention, and
results in significant and sustained improvement in platelet count. It also increasingly
improves renal function across patient groups over time, and is associated with
substantial kidney recovery in patients with aHUS. Soliris was approved for the treatment
of patients with aHUS in the US, Europe, and other countries based on data from the two
prospective studies published in NEJM. The Full Research Report on Alexion Pharmaceuticals
, Inc. - including full detailed breakdown, analyst ratings and price targets - is
available to download free of charge at: [
http://www.wsreports.com/r/full_research_report/451f_ALXN]
--
BioMarin Pharmaceutical Inc. Research Report
On June 5, 2013, BioMarin Pharmaceutical Inc. (BioMarin) announced that it has
initiated the Phase 3 program for PEG-PAL (PEGylated recombinant Phenylalanine Ammonia
Lyase) for the treatment of phenylketonuria (PKU). "Adult patients with PKU and patients
on the severe end of the disease spectrum still represent a very high unmet medical need.
With PEG-PAL, it may be possible to provide a treatment benefit to this population," said
Hank Fuchs, M.D., Chief Medical Officer of BioMarin. The Phase 3 study (165-301) is an
open-label, multi-center study to assess the safety and tolerability of an induction,
titration, and maintenance dose regimen of PEG-PAL self-administered by approximately 90
naive adult PKU subjects. After completion of the open label 165-301 study, subjects are
expected to enroll in 165-302, a Phase 3 double-blind, placebo-controlled, randomized
discontinuation study to evaluate the efficacy and safety of PEG-PAL self-administered by
adults with PKU. The Full Research Report on BioMarin Pharmaceutical Inc. - including full
detailed breakdown, analyst ratings and price targets - is available to download free of
charge at: [http://www.wsreports.com/r/full_research_report/936c_BMRN]
--
Onyx Pharmaceuticals, Inc. Research Report
On June 3, 2013, Onyx Pharmaceuticals, Inc. (Onyx) and the University of California,
San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center announced the
formation of the Oncology Innovation Alliance (OIA). OIA is a public-private partnership
focusing on the discovery and development of novel therapies and their potential role in
treating various types of hematologic cancers and solid tumors. The alliance intends to
transform cancer care by harnessing the expertise in fundamental science and medicine at
both UCSF and Onyx to address the full continuum of that care, from prediction and
diagnosis to new therapies and post-treatment monitoring, to identify opportunities to
improve the patient experience and outcomes. The term of the agreement extends for three
years. The Full Research Report on Onyx Pharmaceuticals, Inc. - including full detailed
breakdown, analyst ratings and price targets - is available to download free of charge at:
[http://www.wsreports.com/r/full_research_report/fcf8_ONXX]
--
Questcor Pharmaceuticals, Inc. Research Report
On June 10, 2013, Questcor Pharmaceuticals, Inc. (Questcor) announced the addition of
Angus C. Russell, recently-retired CEO of Shire plc, to Questcor's Board of Directors.
"Angus is a respected biopharmaceutical industry leader with a proven track in specialty
pharmaceuticals," said Virgil D. Thompson, Chairman of Questcor's Board of Directors. "We
look forward to benefitting from Angus' 32 years of experience in the specialty
pharmaceutical industry as we continue to focus on the treatment of patients with serious,
difficult-to-treat autoimmune and inflammatory disorders." "The growth of scientific
knowledge regarding the importance of melanocortin receptors in immunomodulation provides
Questcor with a large potential growth opportunity over the next few years," Angus added.
Further, on May 29, 2013, the Company's Board of Directors declared a quarterly cash
dividend of $0.25 per share to shareholders of record at the close of business on July 22,
2013, payable on or about July 30, 2013. The Full Research Report on Questcor
Pharmaceuticals, Inc. - including full detailed breakdown, analyst ratings and price
targets - is available to download free of charge at: [
http://www.wsreports.com/r/full_research_report/ad11_QCOR]
--
ImmunoGen, Inc. Research Report
On June 3, 2013, ImmunoGen, Inc. (ImmunoGen) announced the presentation of the first
clinical data with the Company's IMGN853 product candidate. The data belong to the ongoing
dose-finding portion of a Phase I clinical assessment of the compound, which is a
potential treatment for many ovarian, endometrial, and non-small cell lung cancers, as
well as other FRalpha-overexpressing cancers. The dose-finding portion of the Phase I
clinical trial is designed to establish the maximum tolerated dose of IMGN853 and to
define its dose-limiting toxicity (DLT). At the time of data cutoff for presentation, 18
patients had received IMGN853 at doses ranging from 0.15 to 7 mg/kg. DLT, seen at 7 mg/kg,
was reversible blurred vision with epithelial corneal changes. While the assessment is
designed to evaluate the safety of IMGN853 and establish its maximum tolerated dose,
evidence of clinical activity is also being identified. The Company expects to begin the
disease-specific, dose-expansion phase of the trial in late 2013. The Full Research Report
on ImmunoGen, Inc. - including full detailed breakdown, analyst ratings and price targets
- is available to download free of charge at: [
http://www.wsreports.com/r/full_research_report/18c3_IMGN]
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SOURCE Wall Street Reports