Certain Common Stock of Impel NeuroPharma, Inc. are subject to a Lock-Up Agreement Ending on 8-NOV-2021. These Common Stock will be under lockup for 60 days starting from 9-SEP-2021 to 8-NOV-2021. Details: The officers and directors and affiliated funds have agreed that, subject to specified exceptions, for a period of 90 days (or, in the case of affiliated funds, 60 days) from the date of the prospectus, they will not, without the prior written consent of Cowen and Company, LLC and Guggenheim Securities, LLC, dispose of or hedge any shares or any securities convertible into or exchangeable for common stock.