INARI MEDICAL

COMPANY PROFILE - August 2022

Extracting large clots from large vessels without the need for thrombolytics or ICU stay

Inari Medical is committed to treating and transforming the lives of patients suffering from venous diseases through pioneering devices specifically designed and purpose-built for the venous anatomy and its unique clot morphology

CURRENT MARKETS AND PRODUCTS

Offering highly differentiated products in the venous space, treating Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)

PULMONARY EMBOLISM (PE)

THE CHALLENGE:

  • When part of a blood clot travels to the lungs causing a blockage
  • 3rd leading cause of cardiovascular death1
  • Up to 15% 30-day all cause mortality2,3, 28% for high-risk PE2
  • Up to 50% of PE patients have residual vascular obstrubiton4-6, and long-term complications are common7

THE INARI SOLUTION:

The FlowTriever® System

  • A large bore catheter-based aspiration and mechanical thrombectomy system de- signed to remove large clots from large venous vessels, the right heart, pulmonary arteries and the lungs
  • In May of 2018, the FlowTriever System received FDA approved labeling, making it the first mechanical thrombectomy device indicated for the treatment of Pulmo- nary Embolism (PE)
  • In January of 2021, FlowTriever received 510(k) market clearance from the U.S.
    FDA for Right Atrial Clot in Transit becoming the first thrombectomy system not requiring a cardiopulmonary bypass circuit for blood clots in the right atrium

DEEP VEIN THROMBOSIS (DVT)

THE CHALLENGE:

  • Blood clots that form in a deep vein, usually in the lower leg, thigh, or pelvis.
  • Up to 50% of patients are expected to develop post-thrombotic syndrome (PTS)8
  • Nearly 90% of PTS patients are unable to work 10 years after diagnosis9
  • >10% of PTS patients develop venous leg ulcers10

THE INARI SOLUTION:

The ClotTriever® System

  • Designed to core, capture and remove large clots from large venous vessels
  • In February of 2017, the ClotTriever System received 510(k) market clearance from the U.S. FDA for the non-surgical removal of thrombi and emboli from the peripheral vasculature

FINANCIAL PROFILE

Robust quarterly revenue growth with gross margins of >80%

REVENUES

$92.7

$86.8

(LAST 8 QUARTERS, $ IN MILLIONS)

$83.2

$72.9

$63.5

$57.4

$48.6

$38.7

Q3-20

Q4-20

Q1-21

Q2-21

Q3-21

Q4-21

Q1-22

Q2-22

  1. "Pulmonary Embolism in 2017: Increasing Options for Increasing Incidence", National Center for Biotechnology Information, May 2017.
  2. PERT Consortium® Registry Data. Interim results on 5,048 Patients presented at PERT Symposium October 2021​
  3. Schultz J, et al. Pulm Circ. 2019 Jan 11;9(3):2045894018824563;
  4. Chopard et al. 2017. Ame J of Cardiol. Volume 119, Issue 11, 1883-1889 ​
  5. Miniati et al. 2006 Medicine. 85. 253-62. 10.1097/01.md.0000236952.87590.c8​
  6. Mrozek et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 162(2):121-126. doi: 10.5507/bp.2018.001​
  7. Sista AK, et al. Vasc Med. 2017 Feb;22(1):37-43
  8. Kahn, Susan R. Hematology Am Soc Hematol Educ Program. 2016 Dec 2; 2016(1): 413-418
  9. Kahn, et al. Arch Intern Med. 2004;164:17-26
  10. Galanaud, et al. Thromb Haemost 2018; 118(02): 320-328

FAST FACTS

PATIENT-FOCUSED

Pursuing extraordinary outcomes and improving the quality of life for patients since 2011

PRODUCT SIMPLICITY

Intuitive, easy-to-use,single-use devices that do not require capital equipment or the use of thrombolytic drugs

COMPELLING PROCEDURE ECONOMICS Products designed for short, single sessions, eliminating the need for expensive thrombolytics which require costly ICU stays and carry risks of major bleeding

COMMITMENT TO CLINICAL DATA Significant investment into real-worldand broad evidence generation to drive adoption; studies and registries include FLARE, CLOUT, FLASH, FLAME, and PEERLESS

SCALING COMMERCIAL ORGANIZATION Rapidly growing US sales team designed to help hospitals develop programs that systematically identify, triage and treat PE and DVT patients; international expansion commencing in Europe, Asia and Latin America

MARKET OPPORTUNITY

Combined addressable market of $5.8B in the US

alone, plus significant international opportunity

IPO

MARQUEE MED TECH IPO

1st non-biotech IPO post COVID-19 outbreak,

completed May, 2020

(NASDAQ: NARI)

CONTACT INFORMATION

6001 Oak Canyon, Ste #100 Irvine, CA 92618, U.S

Steinenbachgaesslein 49, 4051 Basel, Switzerland

info@inarimedical.com

inarimedical.com

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Disclaimer

Inari Medical Inc. published this content on 04 August 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 04 August 2022 16:07:07 UTC.