April 8 (Reuters) - Eli Lilly and Co and Incyte Corp
said their rheumatoid arthritis drug baricitinib did
not meet the main goal of preventing progression to mechanical
ventilation in hospitalized COVID-19 patients under a late-stage
study.
Patients receiving baricitinib were 2.7% less likely than
those receiving standard of care to progress to ventilation,
which was not statistically significant, the data showed. (https://refini.tv/3t0NfHD)
Baricitinib has been granted emergency use authorization by
the U.S. Food and Drug Administration in combination with
remdesivir for COVID-19 patients requiring supplemental oxygen.
The study enrolled 1,525 hospitalized COVID-19 patients who
received either baricitinib or placebo along with standard of
care including corticosteroids and remdesivir.
Lilly will share the data from the trial with regulatory
authorities in the United States, European Union and other
geographies to evaluate next steps.
(Reporting by Mrinalika Roy in Bengaluru; Editing by Aditya
Soni and Devika Syamnath)