ITEM 1.01 Entry into a Material Definitive Agreement.

On January 4, 2022, Intra-Cellular Therapies, Inc. (the "Company") entered into an underwriting agreement (the "Underwriting Agreement") with J.P. Morgan Securities LLC, SVB Leerink LLC, BofA Securities, Inc., Evercore Group L.L.C. and RBC Capital Markets, LLC, as representatives of the several underwriters named therein (collectively, the "Underwriters"), relating to an underwritten public offering of 9,523,810 shares (the "Underwritten Shares") of the Company's common stock, par value $0.0001 per share (the "Common Stock"). All of the Underwritten Shares are being sold by the Company. The offering price to the public of the Underwritten Shares is $42.00 per share, and the Underwriters have agreed to purchase the Underwritten Shares from the Company pursuant to the Underwriting Agreement at a price of $39.6375 per share. The Company expects to receive net proceeds from the offering of approximately $377.1 million, after deducting underwriting discounts and commissions and estimated offering expenses. Under the terms of the Underwriting Agreement, the Company granted the Underwriters an option, exercisable for 30 days, to purchase up to an additional 1,428,571 shares of Common Stock (the "Option Shares" and together with the Underwritten Shares, the "Shares") at the public offering price less the underwriting discounts and commissions.

The Underwritten Shares and any Option Shares will be issued pursuant to the Company's shelf registration statement on Form S-3 (Registration Statement No. 333-235817) that was previously filed with the Securities and Exchange Commission (the "Commission") on January 6, 2020 and became effective upon filing (the "Registration Statement"). A prospectus supplement relating to the offering has been filed with the Commission. The offering is expected to close on or about January 7, 2022, subject to the satisfaction of customary closing conditions.

A copy of the legal opinion and consent of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. relating to the validity of the issuance and sale of the Shares is attached as Exhibit 5.1 hereto.

The Underwriting Agreement contains customary representations and warranties, agreements and obligations, conditions to closing and termination provisions. The Underwriting Agreement provides for indemnification by the Underwriters of the Company, its directors and certain of its executive officers, and by the Company of the Underwriters, for certain liabilities, including liabilities arising under the Securities Act of 1933, as amended, and affords certain rights of contribution with respect thereto. The foregoing description of the Underwriting Agreement is qualified in its entirety by reference to the Underwriting Agreement, which is attached as Exhibit 1.1 hereto and incorporated by reference herein.

In connection with the offering, certain information relating to Part II, Item 14 of the Registration Statement under the heading "Other Expenses of Issuance and Distribution" is being filed with this Current Report on Form 8-K to be incorporated by reference into the Registration Statement.

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ITEM 8.01 Other Events.

On January 4, 2022, the Company issued a press release announcing the pricing of the underwritten public offering, a copy of which is attached hereto as Exhibit 99.2 and is incorporated herein by reference.

ITEM 9.01 Financial Statements and Exhibits.




(d) Exhibits



Exhibit
Number                                    Description

 1.1           Underwriting Agreement, dated January 4, 2022, by and among the
             Company, J.P. Morgan Securities LLC, SVB Leerink LLC, BofA Securities,
             Inc., Evercore Group L.L.C. and RBC Capital Markets, LLC, as
             representatives of the several underwriters named therein.

 5.1           Opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

23.1           Consent of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
             (contained in Exhibit 5.1).

99.1           Information relating to Item 14 of the Registration Statement on
             Form S-3 (File No. 333-235817).

99.2           Press Release of Intra-Cellular Therapies, Inc., dated January 4,
             2022.

104          Cover Page Interactive Data File (embedded within the Inline XBRL
             document).

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