Itaú Unibanco S A : 1Q 21 Risk and capital management Pillar 3 First quarter of 2021

1Q 21 Risk and capital management Pillar 3 First quarter of 2021

Contents Objective 1 Key indicators 1 Prudential Metrics and Risk Management 2 KM1: Key metrics at consolidated level 2 OVA: Bank risk management approach 3 Scope and main characteristics of risk management 3 Risk and Capital Governance 4 Risk Appetite 4 Risk Culture 5 Stress Testing 5 Recovery Plan 6 Capital Adequacy Assessment 7 Capital Adequacy 7 OV1: Overview of risk-weighted assets (RWA) 8 Links between financial statements and regulatory exposures 9 LIA: Explanations of differences between accounting and regulatory exposure amounts 9 LI1: Differences between accounting and regulatory scopes of consolidation and mapping of financial 10 statement categories with regulatory risk categories LI2: Main sources of differences between regulatory exposure amounts and carrying values in financial 10 statements PV1: Prudent valuation adjustments (PVA) 11 Institutions that comprise the Financial Statement of Itaú Unibanco Holding 12 Non Consolidated Institutions 14 Material Entities 15 Composition of Capital 15 CCA: Main features of regulatory capital instuments 15 CC1: Composition of regulatory capital 16 CC2: Reconciliation of regulatory capital to balance sheet 18 Macroprudential Indicators 19 CCyB1: Geographical distribution of credit risk exposures considered in the calculation of the 19 Countercyclical Capital Buffer GSIB1: Disclosure of G-SIB indicators 19 Leverage Ratio 20 LR1: Summary comparison of accounting assets vs leverage ratio exposure measure (RA) 20 LR2: Leverage ratio common disclosure 20 Liquidity Ratios 21 LIQA: Liquidity Risk Management Information 21 Framework and Treatment 21 LIQ1: Liquidity Coverage Ratio (LCR) 22 LIQ2: Net Stable Funding Ratio (NSFR) 23 Credit Risk 24 CRA: Qualitative information on credit risk management 24 CR1: Credit Quality of Assets 25 CR2: Changes in Stock of defaulted loans and debts securities 25 CRB: Additional disclosure related to the credit quality of assets Credit risk mitigation 25 Exposure by industry 26 Exposure by remaining maturity 26 Overdue exposures 26 Exposure by geographical area in Brazil and by country 27 Largest debtors exposures 27 Restructured exposures 27

CRC: Qualitative disclosure related to Credit Risk Mitigation techniques 28 CR3: Credit Risk mitigation techniques - overview 28 CR4: Standardized Approach - Credit Risk exposure and credit risk mitigation effects 29 CR5: Standardized Approach - exposures by asset classes and risk weights 29 Counterparty Credit Risk (CCR) 30 CCRA: Qualitative disclosure related to CCR 30 CCR1: Analysis of CCR exposures by approach 30 CCR3: Standardized approach - CCR exposures by regulatory portfolio and risk weights 30 CCR5: Composition of collateral for CCR exposures 31 CCR6: CCR associated with credit derivatives exposures 31 CCR8: CCR associated with Exposures to central counterparties 31 Securitization Exposures 32 SECA: Qualitative disclosure requirements related to securitisation exposures 32 SEC1: Securitisation exposures in the banking book 32 SEC2: Securitisation exposures in the trading book 32 SEC3: Securitisation exposures in the banking book and associated regulatory capital requirements - 32 bank acting as originator or as sponsor SEC4: Securitisation exposures in the banking book and associated capital requirements - bank acting as investor 33 Market Risk 34 MRA: Qualitative disclosure requirements related to market risk 34 MR1: Market risk under standardized approach 35 MRB: Qualitative disclosures on market risk in the Internal Models Approach (IMA) 35 MR2: RWA flow statements of market risk exposures under an IMA 37 Exposures subject to market risk 37 MR3: IMA values for trading portfolios 38 MR4: Comparison of VaR estimates with gains/losses 38 Backtesting 38 Total Exposure associated with Derivatives 39 IRRBB 40 IRRBBA: IRRBB risk management objectives and policies 40 Framework and Treatment 40 IRRBB1 - Quantitative information on IRRBB 42 Other Risks 43 Insurance products, pension plans and premium bonds risks 43 Social and Environmental Risk 43 Model Risk 44 Regulatory or Compliance Risk 44 Reputational Risk 44 Country Risk 46 Business and Strategy Risk 46 Contagion Risk 46 Operational Risk 47 Crisis Management and Business Continuity 47 Independent Validation of Risk Models 48 Glossary of Acronyms 49 Glossary of Regulations 52

Risk and Capital Management - Pillar 3 Objective This document presents Itaú Unibanco Holding S.A. (Itaú Unibanco) information required by the Central Bank of Brazil (BACEN) through BCB Resolution nº 54 and subsequent amendments, which addresses the disclosure of information on risks and capital management, the comparison between accounting and prudential information, the liquidity and market risk indicators, the calculation of risk-weighted assets (RWA), the calculation of the Total Capital and the compensation of management members1. The referred Resolution brought several amendments in the disclosure format of the Pillar 3 information, besides changes in the scope and frequency of the information disclosed. All these amendments, implemented by the Central Bank, aim the convergence of the Brazilian financial regulation to the recommendations of the Basel Committee, seeking to harmonize the information disclosed by financial institutions at an international level, and taking into account the structural conditions of the Brazilian economy. The disclosure policy of the Risk and Capital Management Report presents the guidelines and responsibilities of the areas involved in its preparation, as well as the description of the information that must be disclosed and the integrity endorsement and approval governance, as established by the article 56 of the Resolution nº 4,557. Key indicators Itaú Unibanco's risk and capital management focuses on maintaining the institution in line with the risk strategy approved by the Board of Directors. The key indicators based on the Prudential Consolidation, on March 31, 2021, are summarized below. Common Equity Tier I Ratio Tier I Ratio Total Capital Ratio 11.3% 13.0% 14.5% December 31, 2020: 11.5% December 31, 2020: 13.2% December 31, 2020: 14.5% Common Equity Tier I Tier I Total Capital R$ 121,025 million R$ 139,552 million R$ 155,280 million December 31, 2020: R$ 119,960 million December 31, 2020: R$ 137,157 million December 31, 2020: R$ 151,244 million RWA R$ 1,072,193 million December 31, 2020: R$ 1,042,207 million Tier I Capital Ratio

Risk and Capital Management - Pillar 3 Prudential Metrics and Risk Management Itaú Unibanco invests in robust and company-wide risk management processes to serve as a basis for its strategic decisions intended to ensure business sustainability. The key prudential metrics related to regulatory capital and information on the bank's integrated risk management are presented below. KM1: Key metrics at consolidated level In order to ensure the soundness of Itaú Unibanco and the availability of capital to support business growth, Itaú Unibanco maintains capital levels above the minimum requirements, as demonstrated by the Common Equity Tier I, Tier I Capital and Total CapitaI ratios. On March 31, 2021, the Total Capital (PR) reached R$ 155,280 million, R$ 139,552 million of Tier I and R$ 15,728 million of Tier II. R$ million 03/31/2021 12/31/2020 09/30/2020 06/30/2020 03/31/2020 Available capital (amounts) Common Equity Tier 1 (CET1) 121,025 119,960 113,910 108,119 107,668 Tier 1 139,552 137,157 132,272 126,214 124,980 Total capital 155,280 151,244 146,894 140,650 139,218 Excess of capital committed to adjusted permanent assets - --Total capital detached - --Risk-weighted assets (amounts) Total risk-weighted assets (RWA) 1,072,193 1,042,207 1,068,739 1,040,622 1,043,517 Risk-based capital ratios as a percentage of RWA Common Equity Tier 1 ratio (%) 11.3% 11.5% 10.7% 10.4% 10.3% Tier 1 ratio (%) 13.0% 13.2% 12.4% 12.1% 12.0% Total capital ratio (%) 14.5% 14.5% 13.7% 13.5% 13.3% Additional CET1 buffer requirements as a percentage of RWA Capital conservation buffer requirement (%) (1) 1.25% 1.25% 1.25% 1.25% 2.5% Countercyclical buffer requirement (%) (2) 0.0% 0.0% 0.0% 0.0% 0.0% Bank G-SIB and/or D-SIB additional requirements (%) 1.0% 1.0% 1.0% 1.0% 1.0% Total of bank CET1 specific buffer requirements (%) (3) 2.25% 2.25% 2.25% 2.25% 3.5% CET1 available after meeting the bank's minimum capital requirements (%) 4.1% 4.1% 3.3% 3.1% 1.6% Basel III leverage ratio Total Basel III leverage ratio exposure measure 1,918,231 1,903,298 1,914,229 1,853,479 1,743,174 Basel III leverage ratio (%) 7.3% 7.2% 6.9% 6.8% 7.2% Liquidity Coverage Ratio Total high-quality liquid assets (HQLA) 356,222 343,174 328,202 283,267 186,705 Total net cash outflow 186,513 176,355 168,331 158,126 112,841 LCR (%) 191.0% 194.6% 195.0% 179.1% 165.5% Net Stable Funding Ratio Total available stable funding 990,197 956,033 932,718 892,597 811,680 Total required stable funding 792,199 758,907 754,386 728,795 695,135 NSFR (%) 125.0% 126.0% 123.6% 122.5% 116.8% (1) For purposes of calculating the Conservation capital buffer, BACEN Resolution 4,783 establishes, for defined periods, percentages to be applied to the RWA value with a gradual increase until April/22, when it reaches 2.5% . (2) The countercyclical capital buffer is fixed by the Financial Stability Committee (Comef) based on discussions about the pace of credit expansion and currently is set to zero (BACEN Communication No. 36,830/21),. Should the requirement increase, the new percentage takes effect twelve months after the announcement. (3) The BACEN rules establish Capital Buffers, that corresponds to the sum of the Conservation, Contracyclical and Systemic requirements, as defined in CMN Resolution 4,193. The Total Capital Ratio reached 14.5% on March 31, 2021, maintaining the same level when compared to December 31, 2020. The mainly positive effects are the net income in the period and the issuance of Tier 2 Subordinated Notes offset by the increase in the Credit Risk Weighted Assets and in the prudential adjustments. Besides, Itaú Unibanco has a R$ 69,505 million capital excess in relation to its minimum required Total Capital. It corresponds to 650 basis points above the minimum requirement (8%) and higher than the Capital Buffer requirement of 225 basis points (R$ 24.124 million). Considering the Capital Buffers, the capital excess would be 425 basis points. 2 Itaú Unibanco

Risk and Capital Management - Pillar 3 In December 2020, Itaú Unibanco Holding issued R$ 2.1 billion in Financial Subordinated Notes. These Financial Subordinated Notes have a repurchase option as from 2025 and were approved by BACEN for the composition of Tier 2 Capital, according to the eligible value, with an increase of 0.20 p.p. in its Basel Ratio. In January 2021, Itaú Unibanco Holding issued US$ 500 million in Subordinated Notes with maturity term of 10 years and 3 months. These notes were approved by BACEN for the composition of Tier 2 Capital, with an increase of 0.25 p.p. in its Basel Ratio. The fixed assets ratio shows the commitment percentage of the adjusted Referential Equity with the adjusted permanent assets. Itaú Unibanco falls within the maximum limit of 50% of adjusted PR, established by BACEN. On March 31, 2021, fixed assets ratio reached 23.1%, showing a surplus of R$ 41.805 million. OVA - Bank risk management approach Scope and main characteristics of risk management To undertake and manage risks is one of the activities of Itaú Unibanco. For this reason, the institution must have clearly established risk management objectives. In this context, the risk appetite defines the nature and the level of risks acceptable for the institution, while the risk culture guides the attitudes required to manage them. Itaú Unibanco invests in robust risk management processes, that are the basis for its strategic decisions to ensure business sustainability and maximize shareholder value creation. These processes are in line with the guidelines of the Board of Directors and Executives who, through corporate bodies, define the institution's global objectives, which are then translated into targets and thresholds for the business units that manage risks. Control and capital management units, in turn, support Itaú Unibanco's management through the processes of analysis and monitoring of capital and risk. The principles that provide the risk management and the risk appetite foundations, as well as guidelines regarding the actions taken by Itaú Unibanco's employees in their daily routines are as follows: • Sustainability and customer satisfaction: the vision of Itaú Unibanco is to be a leading bank in sustainable performance and customer satisfaction. For this reason, the institution is concerned about creating shared values for employees, customers, shareholders and society to ensure the longevity of the business. Itaú Unibanco is concerned about doing business that is good for customers and for the institution; • Risk culture: the institution's risk culture goes beyond policies, procedures and processes. It strengths the individual and collective responsibility of all employees to manage and mitigate risks consciously, respecting the ethic way of doing business. The risk culture is described in the item 'Risk Culture'; • Risk Pricing: Itaú Unibanco operates and assumes risks in business that it knows and understands, avoids the ones that are unknown or that do not provide competitive advantages, and carefully assesses risk-return ratios; • Diversification: the institution has low appetite for volatility in its results. Accordingly, it operates with a diversified base of customers, products and business, seeking risk diversification and giving priority to low-risk transactions; • Operational excellence: Itaú Unibanco intends to provide agility, as well as a robust and stable infrastructure, in order to offer high quality services; • Ethics and respect for regulations: at Itaú Unibanco, ethics is non-negotiable. For this reason, the institution promotes an institutional environment of integrity, educating its employees to cultivate ethical relationships and businesses, as well as respecting the norms, and therefore looking after the institution's reputation. Since August, 2017, the Resolution CMN 4,557 came into force, which established the structure of risk and capital management. The resolution highlights are the implementation of a continuous and integrated risk management framework; the requirements for the definition of the Risk Appetite Statement (RAS) and the stress 3 Itaú Unibanco

Risk and Capital Management - Pillar 3 test program; the establishment of a Risk Committee; the indication, before BACEN, of the Chief Risk Officer (CRO); and the CRO's roles, responsibilities and independence requirements. Risk and Capital Governance The Board of Directors is the main body responsible for establishing the guidelines, policies and authority levels regarding risk and capital management. In turn, the Risk and Capital Management Committee (CGRC) provides support to the Board of Directors in the performance of their duties relating to risk and capital management. At the executive level, corporate bodies headed by Itaú Unibanco's Chief Executive Officer (CEO) are established to manage risks and capital. Their decisions are overseen by the CGRC. Additionally, Itaú Unibanco has corporate bodies that perform delegated duties in the risk and capital management, under the responsibility of the CRO (Chief Risk Officer). To support this structure, the Risk Area is structured with specialized departments. The objective is to provide independent and centralized management of the institution's risks and capital, and to ensure the accordance with the established rules and procedures. Itaú Unibanco's risk management organizational structure complies with Brazilian and international regulations in place and is aligned with the market's best practices. Responsibilities for risk management at Itaú Unibanco are structured according to the concept of three lines of defense, namely: • in the first line of defense, the business and corporate support areas manage risks they give rise to, by identifying, assessing, controlling and reporting such risks; • in the second line of defense, an independent unit provides central control, so as to ensure that Itaú Unibanco's risk is managed according to the risk appetite and established policies and procedures. This centralized control provides the Board and executives with a global overview of Itaú Unibanco's exposure, to ensure correct and timely corporate decisions; • in the third line of defense, internal audit provides an independent assessment of the institution's activities, so that senior management can see that controls are adequate, risk management is effective and institutional standards and regulatory requirements are being complied with. Itaú Unibanco uses robust automated systems for full compliance with capital regulations, as well as for measuring risks in accordance with the regulatory determinations and models in place. It also monitors adherence to the qualitative and quantitative regulators' minimum capital and risk management requirements. Risk Appetite Itaú Unibanco has a risk appetite policy, which was established and approved by the Board of Directors and guides the institution's business strategy. The bank's risk appetite is grounded on the following declaration of the Board of Directors: 'We are a universal bank, operating predominantly in Latin America. Supported by our risk culture, we operate based on rigorous ethical and regulatory compliance standards, seeking high and growing results, with low volatility, by means of the long-lasting relationship with clients, correctly pricing risks, well-distributed fund-raising and proper use of capital.' Based on this declaration, the bank established five dimensions, each of which comprising a set of metrics associated with the key risks involved, combining complementary measurements and seeking a comprehensive view of its exposure: • Capitalization: establishes that Itaú Unibanco should have sufficient capital to protect itself against a serious recession or stress events without the need to adjust its capital structure under adverse circumstances. It is monitored by following up the bank's capital ratios, in usual or stress situations, and the institution's debt issue ratings. • Liquidity: establishes that the institution's liquidity should be able to support long stress periods. It is monitored by following up on liquidity ratios. 4 Itaú Unibanco

Risk and Capital Management - Pillar 3 • Composition of results: establishes that business will mainly focus on Latin America, where Itaú Unibanco will have a diversified range of customers and products, with low appetite for results volatility and high risk. This dimension includes business and profitability, as well as market and credit risks aspects. The metrics monitored by the bank seek to ensure, by means of exposure concentration limits such as, for example, industry sectors, quality of counterparties, countries and geographic regions and risk factors, a suitable composition of the bank's portfolios, aiming at low volatility of results and business sustainability. • Operational risk: focuses on controlling operational risk events that may adversely impact the bank's business strategy and operations. This control is carried out by monitoring key operational risk events and incurred losses. • Reputation: deals with risks that may impact brand value and the institution's reputation before its customers, employees, regulators, investors and the general public. In this dimension, risks are monitored by following up on customers' satisfaction or dissatisfaction, media exposure and observation of the institution's conduct. The Board of Directors is responsible for approving risk appetite guidelines and limits, performing its activities with the support of the Risk and Capital Management Committee (CGRC) and the Chief Risk Officer (CRO). Metrics are regularly monitored and must comply with the limits defined. The monitoring is reported to the risk commissions and to the Board of Directors, guiding the use of preventive measures to ensure that exposures are within the limits provided and in line with the bank's strategy. Risk Culture Aiming at strengthening its values and aligning the behavior of its employees with risk management guidelines, the institution adopts several initiatives to disseminate and strengthen its Risk Culture, which is based on four principles: conscious risk taking, discussions and actions on the institution's risks, and each and everyone's responsibility for risk management. Besides the risk management policies, procedures and processes, the institution promotes its Risk Culture by emphasizing a behavior that helps people of all company levels to undertake and manage risks in a conscious way. By disseminating these principles, the institution fosters the understanding and the open discussion about risks, so that they are kept within the risk appetite levels established and each employee individually, regardless of their position, area or duties, may also assume responsibility for managing the risks of the business. Itaú Unibanco also makes some channels available for communication of operating failures, internal or external fraud, conflicts at the workplace, or cases that may result in inconveniences and/or losses for the institution or its customers. All employees or third parties are responsible for informing any problems immediately, as soon as they become aware of the situation. Stress Testing The stress test is a process of simulating extreme economic and market conditions on Itaú Unibanco's results, liquidity and capital. The institution has been carrying out this test in order to assess its solvency in plausible scenarios of crisis, as well as to identify areas that are more susceptible to the impact of stress that may be the subject of risk mitigation. For the purposes of the test, the economic research area estimates macroeconomic variables for each stress scenario. The elaboration of stress scenarios considers the qualitative analysis of the Brazilian and the global conjuncture, historical and hypothetical elements, short and long term risks, among other aspects, as defined in CMN Resolution 4,557. In this process, the main potential risks to the economy are assessed based on the judgment of the bank's team of economists, endorsed by the Chief Economist of Itaú Unibanco and approved by the Board of Directors. Projections for the macroeconomic variables (such as GDP, the basic interest rate and inflation) and for variables in the credit market (such as raisings, lending, rates of default, margins and charges) used are based on exogenous shocks or through use of models validated by an independent area. 5 Itaú Unibanco

Risk and Capital Management - Pillar 3 Then, the stress scenarios adopted are used to influence the budgeted result and balance sheet. In addition to the scenario analysis methodology, sensitivity analysis and the Reverse Stress Test are also used. Itaú Unibanco uses the simulations to manage its portfolio risks, considering Brazil (segregated into wholesale and retail) and External Units, from which the risk-weighted assets and the capital and liquidity ratios are derived. The stress test is also an integral part of the ICAAP (Internal Capital Adequacy Process), the main purpose of which is to assess whether, even in severely adverse situations, the institution would have adequate levels of capital and liquidity, without any impact on the development of its activities. This information enables potential offenders to the business to be identified and provides support for the strategic decisions of the Board of Directors, the budgeting and risk management process, as well as serving as an input for the institution's risk appetite metrics. Recovery Plan In response to the latest international crises, the Central Bank issued the Resolution No. 4,502, which requires the development of a Recovery Plan for the financial institutions that are classified in the Segment 1, with a total exposure of more than 10% of Gross Domestic Product (GDP). This plan aims to reestablish adequate levels of capital and liquidity, above the regulatory requirements, through appropriate strategies in the event of severe stress shocks of a systemic or idiosyncratic nature. Accordingly, each institution would be able to preserve its financial feasibility and, at the same time, mitigate the impact on the National Financial System. Itaú Unibanco has a Recovery Plan that contemplates the entire conglomerate, including foreign subsidiaries, and contains the description of the following items: I. Critical functions rendered by Itaú Unibanco to the market, activities that, if abruptly interrupted, could impact the National Financial System (SFN) and the functioning of the real economy; II. Institution's essential services: activities, operations or services which discontinuity could compromise the bank's viability; III. Monthly monitoring program, establishing critical levels for a set of indicators, with a view to risk monitoring and eventual trigger for the execution of the Recovery Plan; IV. Stress scenarios, contemplating events that may threaten the business continuity and the viability of the institution, including reverse tests, which seek to identify remote risk scenarios, contributing to an increase of the management sensitivity; V. Recovery strategies in response to different stress scenarios, including the main risks and barriers, as well as the mitigators of the latter and the procedures for the operationalization of each strategy; VI. Communication plan with stakeholders, seeking its timely execution with the market, regulators and other stakeholders; VII. Governance mechanisms necessary for the coordination and execution of the Recovery Plan, such as the definition of the director responsible for the exercise at Itaú Unibanco. This plan is reviewed annually and is subjected to the approval of the Board of Directors. With this practice, Itaú Unibanco has been able to continuously demonstrate, since its first edition in 2017, that even in severe scenarios, with remote probability of occurrence, it has strategies capable of generating sufficient resources to ensure the sustainable maintenance of critical activities and essential services, without losses to customers, to the financial system and to other participants in the markets in which it operates. Itaú Unibanco ensures the exercise maintenance to guarantee that strategies remain up-to-date and viable in the face of organizational, competitive or systemic changes. 6 Itaú Unibanco

Risk and Capital Management - Pillar 3 Capital Adequacy Assessment For its capital adequacy assessment process, the annual Itaú Unibanco's procedure is as follows: • Identification of material risks and assessment of the need for additional capital; • Preparation of the capital plan, both in normality and stress situations; • Internal assessment of capital adequacy; • Structuring of capital contingency and recovery plans; • Preparation of management and regulatory reports. By adopting a prospective stance regarding capital management, Itaú Unibanco implemented its capital management structure and its ICAAP in order to comply with National Monetary Council (CMN) Resolution 4,557, BACEN Circular 3,846 and BACEN Circular Letter 3,907. The result of the last ICAAP, which includes stress tests - dated as of December 2020 - showed that, in addition to having enough capital to face all material risks, Itaú Unibanco has a significant buffer, thus ensuring the soundness of its equity position. Capital Adequacy Itaú Unibanco, through the ICAAP process, assesses the adequacy of its capital to face the incurred risks, composed by regulatory capital for credit, market and operational risks and by the necessary capital to face other risks. In order to ensure the soundness and the availability of Itaú Unibanco's capital to support business growth, the Total Capital levels were maintained above the minimum requirements. 7 Itaú Unibanco

Risk and Capital Management - Pillar 3 OV1 - Overview of risk-weighted assets (RWA) According to CMN Resolution 4,193 and subsequent amendments, for assessing the minimum capital requirements, the RWA must be calculated by adding the following risk exposures: RWA = RWACPAD + RWAMINT + RWAOPAD • RWACPAD = portion related to exposures to credit risk, calculated using standardized approach; • RWAMINT = portion related to the market risk capital requirement, made up of the maximum between the internal model and 80% of the standardized model, and regulated by BACEN Circulars 3,646 and 3,674; • RWAOPAD = portion related to the operational risk capital requirement, calculated using standardized approach. RWA Minimum capital requirements R$ million 03/31/2021 12/31/2020 03/31/2021 Credit Risk: standardized approach 963,403 921,934 77,073 Credit risk (excluding counterparty credit risk) 820,024 778,153 65,602 Counterparty credit risk (CCR) 45,217 45,674 3,618 Of which: standardized approach for counterparty credit risk (SA-CCR) 27,544 27,119 2,204 Of which: Current Exposure Method approach (CEM) --Of which: other CCR 17,673 18,555 1,414 Credit valuation adjustment (CVA) 6,960 5,960 557 Equity investments in funds-look-through approach 6,950 4,897 556 Equity investments in funds-mandate-based approach-623-Equity investments in funds-fall-back approach 1,265 716 101 Securitisation exposures-standardized approach 1,174 1,506 94 Amounts below the thresholds for deduction 81,813 84,405 6,545 Market risk 26,764 27,481 2,141 Of which: standardized approach 33,455 34,351 2,676 Of which: internal models approach (IMA) 25,227 22,362 2,018 Operational risk 82,026 92,792 6,562 Total 1,072,193 1,042,207 85,776 The increase of R$ 29,986 million in the Risk-Weighted Assets (RWA) was mainly driven by the Credit Risk Weighted Assets (RWACPAD) due to an increase in the loan portfolio during the period, especially in the wholesale banking segment, and the foreign exchange variation. 8 Itaú Unibanco

Risk and Capital Management - Pillar 3 Links between financial statements and regulatory exposures LIA: Explanations of differences between accounting and regulatory exposure amounts The main difference between the accounting carrying value and the amounts considered for regulatory purposes is the non-consolidation of non-financial companies (especially Insurance, Pension Plan and Capitalization companies) in the regulatory consolidated, a difference that also impacts the elimination of related parties transactions. Within the regulatory scope, the procedures for assessing the need for prudent valuation adjustments (PVAs) arising from the pricing of financial instruments, as well as the description of the systems and controls used to ensure its reliability are described below. The pricing methodology for the financial instruments subject to Resolution No. 4,277, of October 31st, 2013, conducted by an independent area from the business areas, considers, in addition to benchmarks, the risks listed in the closeout uncertainty, market concentration, early termination, model risk, investing and funding costs, unearned credit spread and others. The fair value measurement at Itaú Unibanco follows the principles enclosed in the main regulatory bodies, such as CVM and BACEN. The institution follows the best practices in terms of pricing policies, procedures and methodologies and is committed to secure the pricing of financial instruments in its balance sheet with prices quoted and disclosed by the market, and in the impossibility of doing so, expends its best efforts to estimate which would be the fair price at which financial assets would be effectively traded, maximizing the use of relevant observable data and, under specific conditions, these instruments can be valued on a model basis. In all of these situations, the organization has control over its pricing methods and model risk management. The process of independent price verification (IPV) follows the guidelines included in Resolution No. 4,277, with daily verification of prices and market inputs, which is performed by a team independent from the pricing team. This process is also subject to an independent evaluation by the internal control, internal audit and external audit teams. The institution has a hybrid model for assessing the need for prudent valuation adjustments with two components. The first component is a timely assessment model that assesses new products, operations and risk factors traded and verifies the compliance and liability with any components of the existing prudent valuation adjustments. The second is a periodic assessment that aims to analyze the existing prudent valuation adjustments in relation to adequate pricing. The process and methodology are evaluated periodically and independently by internal controls and internal audit. In the line Other Differences of the table LI2, are reported the transactions subject to credit risk and counterparty credit risk, which are not accounted for in the balance sheet or in the off-balance sheet amounts. 9 Itaú Unibanco

Risk and Capital Management - Pillar 3 LI1: Differences between accounting and regulatory scopes of consolidation and mapping of financial statement categories with regulatory risk categories R$ million, at the end of the period 03/31/2021 Carrying values of items: Carrying values as Carrying Not subject to values under Subject to capital reported in Subject to Subject to the Subject to the scope of counterparty requirements or published credit risk securitisation market risk regulatory credit risk subject to financial framework framework framework statements consolidation framework deduction from capital Assets Current assets and Long-term receivables 2,087,728 1,857,593 1,463,882 352,637 7,006 308,173 29,768 Cash 39,369 39,285 39,285 - 10,541-Interbank investments 252,251 251,125 73,067 178,058-8,133-Securities and derivative financial instruments 734,593 510,000 423,185 73,927 7,006 116,712 1,581 Interbank accounts 137,254 137,255 127,725 --9,530 Interbranch accounts 322 322 - - 322 Loan, lease and other credit operations 687,447 688,302 680,256 - 63,398 8,046 Other receivables 233,326 228,220 117,279 100,652-109,389 10,289 Deferred tax assets-63,723 53,582 --10,141 Sundry-164,497 63,697 100,652-109,389 148 Other assets 3,166 3,085 3,085 - - Permanent assets 37,089 59,530 35,940 --23,590 Investments 16,517 40,259 29,921 --10,338 Real estate 6,405 5,915 5,915 - - Goodwill and Intangible assets 14,167 13,356 104 --13,252 Goodwill-3,872 - - 3,872 Intangible assets-9,380 - - 9,380 Other-104 104 - - Total assets 2,124,817 1,917,123 1,499,822 352,637 7,006 308,173 53,358 Liabilities Current and Long-term Liabilities 1,969,123 1,761,372-285,826-205,545 1,475,546 Deposits 821,379 826,548 --43,899 826,548 Deposits received under securities repurchase agreements 261,774 265,329-244,378-2,237 20,951 Funds from acceptances and issuance of securities 140,351 140,351 --17,124 140,351 Interbank accounts 52,518 52,518 - - 52,518 Interbranch accounts 9,094 9,098 --171 9,098 Borrowings and onlending 88,393 88,393 --9,072 88,393 Derivative financial instruments 73,615 73,201-41,448-3,127 31,753 Technical provision for insurance, pension plan and capitalization 220,441 - - - Provisions 17,137 16,714 - - 16,714 Allowance for financial guarantees provided 802 802 - - 802 Other liabilities 283,619 288,418 --129,915 288,418 Deferred tax liabilities-3,198 - - 3,198 Sundry-285,220 --129,915 285,220 Deferred income 3,346 3,378 - - 3,378 Total liabilities 1,972,469 1,764,750-285,826-205,545 1,478,924 LI2: Main sources of differences between regulatory exposure amounts and carrying values in financial statements R$ million, at the end of the period 03/31/2021 Carrying values of items: Subject to Subject to Subject to the Subject to the Total counterparty credit risk securitisation market risk credit risk framework framework framework framework Asset carrying value amount under scope of regulatory consolidation 1,863,765 1,499,822 352,637 7,006 308,173 Liabilities carrying value amount under regulatory scope of consolidation 285,826-285,826-205,545 Total net amount under regulatory scope of consolidation 1,577,939 1,499,822 66,811 7,006 102,628 Off-balance sheet amounts 160,403 133,517 26,886 - Differences in valuations - --Other differences 87,567 (7,507) 95,074 - Exposure amounts considered for regulatory purposes 1,825,909 1,625,832 188,771 7,006 102,628 10 Itaú Unibanco

Risk and Capital Management - Pillar 3 PV1: Prudent valuation adjustments (PVA) R$ million 03/31/2020 Interest Of which: In Of which: In Equity FX Credit Commodities Total the trading the banking rates book book Closeout uncertainty, of which:-2-41-43 3 40 Closeout cost-2-35-37 3 34 Concentration --6-6-6 Early termination-18-18-36-36 Model risk-107-89-196 3 193 Operational risk - - - - Investing and funding costs - - - - Unearned credit spreads - - - - Future administrative costs - - - - Other - - - - Total adjustment-127-148-275 6 269 11 Itaú Unibanco

Risk and Capital Management - Pillar 3 Institutions that comprise the Financial Statements of Itaú Unibanco Holding The lists below provide the institutions that comprise the financial statements and the Prudential Consolidation of Itaú Unibanco Holding S.A.. Institutions that comprise the financial statements and the Prudential Consolidation(1) Country(2) % Equity share on capital A1 Hedge Orange Master Fundo de Investimento Multimercado Brazil 100.00% Aj Títulos Públicos Fundo de Investimento Renda Fixa Referenciado DI Brazil 98.34% Banco Investcred Unibanco S.A. Brazil 50.00% Banco Itaú (Suisse) S.A. Switzerland 100.00% Banco Itaú Argentina S.A. Argentina 100.00% Banco Itaú BBA S.A. Brazil 100.00% Banco Itaú Consignado S.A. Brazil 100.00% Banco Itaú International United States 100.00% Banco Itaú Paraguay S.A. Paraguay 100.00% Banco Itaú Uruguay S/A Uruguay 100.00% Banco Itaú Veículos S.A. Brazil 100.00% Banco ItauBank S.A. Brazil 100.00% Banco Itaucard S.A. Brazil 100.00% Banco Itauleasing S.A. Brazil 100.00% Dibens Leasing S.A.-Arrendamento Mercantil Brazil 100.00% Financeira Itaú CBD S.A. Crédito, Financiamento e Investimento Brazil 50.00% Fundo A1 Hedge Orange Fundo de Investimento em Cotas de Fundos de Investimento Multimercado Brazil 100.00% Fundo De Invest Dir Creditórios Não Padron NPL II Brazil 100.00% Fundo de Investimento em Direitos Creditórios Não-Padronizados Barzel Brazil 100.00% Fundo em Direitos Creditórios Cielo Emissores I Brazil 89.99% Fundo Fortaleza de Investimento Imobiliário Brazil 100.00% Fundo Kinea Ações Brazil 99.29% Goal Performance Argentina 100.00% Goal Performance II Argentina 100.00% Hipercard Banco Múltiplo S.A. Brazil 100.00% Intrag Distribuidora de Títulos e Valores Mobiliários Ltda. Brazil 100.00% Iresolve Companhia Securitizadora de Créditos Financeiros S.A. Brazil 100.00% Itaú (Panamá) S.A. Panama 34.16% Itaú Administradora de Consórcios Ltda. Brazil 100.00% Itaú Asset Management Colombia S.A. Sociedad Fiduciaria Colombia 34.15% Itaú Bank & Trust Bahamas Ltd. Bahamas 100.00% Itaú Bank & Trust Cayman Ltd. Cayman Islands 100.00% Itaú Bank, Ltd. Cayman Islands 100.00% Itaú BBA Europe S.A. Portugal 100.00% Itaú BBA International Plc. United Kingdom 100.00% Itaú BBA USA Securities Inc. United States 100.00% Itaú Cia. Securitizadora de Créditos Financeiros Brazil 100.00% Itaú Comisionista de Bolsa Colombia S.A. Colombia 34.27% Itaú CorpBanca Chile 39.22% Itaú CorpBanca Colombia S.A. Colombia 34.16% Itaú CorpBanca New York Branch United States 39.22% Itaú Corredores de Bolsa Limitada Chile 39.22% Itaú Corretora de Valores S.A. Brazil 100.00% Itaú Distribuidora de Títulos e Valores Mobiliários S.A. Brazil 100.00% Itaú EU Lux-Itaú Latin America Equity Fund Luxembourg 94.38% Itaú International Securities Inc. United States 100.00% Itaú Invest Casa de Bolsa S.A. Paraguay 100.00% Itaú Kinea Private Equity Multimercado Fundo de Investimento em Cotas de Fundos de Investimento Brazil 100.00% Itaú Securities Services Colombia S.A. Sociedad Fiduciaria Colombia 34.44% Itaú Unibanco Holding S.A. Brazil 100.00% Itaú Unibanco Holding S.A., Grand Cayman Branch Cayman Islands 100.00% Itaú Unibanco S.A. Brazil 100.00% Itaú Unibanco S.A., Grand Cayman Branch Cayman Islands 100.00% Itaú Unibanco S.A., Miami Branch United States 100.00% Itaú Unibanco S.A., Nassau Branch Bahamas 100.00% Itaú Unibanco Veículos Administradora de Consórcios Ltda. Brazil 100.00% Itaú Valores S.A. Argentina 100.00% (1) As of December 2019, the funds Crédito Universitário FIDC I and Crédito Universitário FIDC II were consolidated in the Itaú Unibanco Holding S.A Prudential Conglomerate. (2) The institutions operate in their respective countries of origin. 12 Itaú Unibanco

Risk and Capital Management - Pillar 3 Institutions that comprise the financial statements and the Prudential Consolidation(1) Country (2) % Equity share on capital Itauvest Distribuidora de Títulos e Val. Mobiliários S.A. Brazil 100.00% ITB Holding Ltd. Cayman Islands 100.00% Kinea Ações Fundo de Investimento em Ações Brazil 100.00% Kinea Ações Fundo de Investimento em Cotas de Fundos de Investimento em Ações Brazil 100.00% Kinea CO-investimento Fundo de Investimento Imobiliario Brazil 99.90% Kinea I Private Equity FIP Multiestrategia Brazil 99.66% Kinea II Macro Fundo de Investimento Multimercado Crédito Privado Brazil 100.00% Kinea KP Fundo de Investimento Multimercado Crédito Privado Brazil 100.00% Kinea Oportunidade FI RF Credito Privado Brazil 54.31% Kinea Ventures FIP Brazil 100.00% Licania Fund Limited Cayman Islands 100.00% Luizacred S.A. Sociedade de Crédito, Financiamento e Investimento Brazil 50.00% MCC S.A. Corredores de Bolsa Chile 100.00% Microinvest S.A. Soc. de Crédito a Microempreendedor Brazil 100.00% OCA Dinero Electrónico S.A. Uruguay 100.00% OCA S.A. Uruguay 100.00% Oiti Fundo de Investimento Multimercado Crédito Privado Investimento no Exterior Brazil 100.00% RedeCard S.A. Brazil 100.00% RT Itaú DJ Títulos Públicos Fundo de Investimento Renda Fixa Referenciado DI Brazil 100.00% RT Scala Renda Fixa-Fundo de Investimento em Cotas de Fundos de Investimento Brazil 100.00% RT Voyager Renda Fixa Crédito Privado-Fundo de Investimento Brazil 100.00% Tarumã Fundo Incentivado de Investimento em Debêntures de Infraestrutura Renda Fixa Crédito Privado Brazil 100.00% (1) As of December 2019, the funds Crédito Universitário FIDC I and Crédito Universitário FIDC II were consolidated in the Itaú Unibanco Holding S.A Prudential Conglomerate. (2) The institutions operate in their respective countries of origin. Institutions that comprise only the Financial Statements Country (1) % Equity share on capital Aj II Títulos Públicos Fundo de Investimento Renda Fixa Referenciado DI Brazil 57.95% Albarus S.A. Paraguay 100.00% Ank Platform S.A. Argentina 100.00% BICSA Holdings, Ltd. Cayman Islands 100.00% Borsen Renda Fixa Crédito Privado-Fundo de Investimento Brazil 100.00% CGB II SPA Chile 100.00% CGB III SPA Chile 100.00% Cia. Itaú de Capitalização Brazil 100.00% Estrel Serviços Administrativos S.A. Brazil 100.00% FC Recovery S.A.U. Argentina 100.00% FIC Promotora de Vendas Ltda. Brazil 50.00% iCarros Ltda. Brazil 100.00% IGA Participações S.A. Brazil 100.00% Investimentos Bemge S.A. Brazil 86.81% Itaú Administradora General de Fondos S.A. Chile 39.22% Itaú Asesorías Financieras Limitada Chile 39.22% Itaú Asia Limited Hong Kong 100.00% Itaú Asset Management S.A. Sociedad Gerente de Fondos Comunes de Inversión Argentina 100.00% Itaú Bahamas Directors Ltd. Bahamas 100.00% Itaú Bahamas Nominees Ltd. Bahamas 100.00% Itaú BBA International (Cayman) Ltd. Cayman Islands 100.00% Itaú BBA México, S.A. de C.V. Uruguay 100.00% Itaú BBA Trading S.A. Brazil 100.00% Itaú Chile Inversiones, Servicios y Administracion S.A. Chile 100.00% Itaú Consultoria de Valores Mobiliários e Participações S.A. Brazil 100.00% Itaú Corredor de Seguros Colombia S.A. Colombia 31.37% Itaú Corredores de Seguros S.A. Chile 39.22% Itaú Corretora de Seguros S.A. Brazil 100.00% Itaú Europa Luxembourg S.A. Luxembourg 100.00% Beta Correspondente e Tecnologia Ltda.(2) Brazil 100.00% Itaú Institucional Renda Fixa Fundo de Investimento Brazil 100.00% Itaú International Holding Limited United Kingdom 100.00% Itaú Participação Ltda. Brazil 100.00% Itaú Rent Administração e Participações Ltda. Brazil 100.00% Itaú Seguros Paraguay S.A.(3) Paraguay 100.00% (1) The institutions operate in their respective countries of origin. (2) Current denomination of Itaú Gestão de Vendas Ltda. (3) Current denomination of Providencia S.A. de Seguros. 13 Itaú Unibanco

Risk and Capital Management - Pillar 3 Institutions that comprise only the Financial Statements Itaú Seguros S.A. Itaú USA Asset Management Inc. Itaú Vida e Previdência S.A. Itauseg Participações S.A. Itauseg Saúde S.A. Itauseg Seguradora S.A. ITB Holding Brasil Participações Ltda. IU Corretora de Seguros Ltda. Karen International Limited Kinea Investimentos Ltda. Itaú Unibanco Comercializadora de Energia Ltda.(2) Maxipago Serviços de Internet Ltda. MCC Asesorías SpA Mundostar S.A. Nevada Woods S.A. Proserv-Promociones y Servicios, S.A. de C.V. Provar Negócios de Varejo Ltda. Recaudaciones y Cobranzas Limitada Recovery do Brasil Consultoria S.A. RT Alm 5 Fundo de Investimento Renda Fixa RT Alm Soberano 2 Fundo de Investimento Renda Fixa RT Defiant Multimercado-Fundo de Investimento RT Endeavour Renda Fixa Crédito Privado-Fundo de Investimento RT Multigestor 4 Fundo de Investimento em Cotas de Fundos de Investimento Multimercado RT Nation Renda Fixa-Fundo de Investimento RT Valiant Renda Fixa-Fundo de Investimento SAGA II SPA SAGA III SPA Topaz Holding Ltd. Tulipa S.A. Uni-Investment International Corporation Unión Capital AFAP S.A. Zup I.T. Soluções em Informatica LTDA. Country (1) % Equity share on capital Brazil 100.00% United States 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Bahamas 100.00% Brazil 80.00% Brazil 100.00% Brazil 100.00% Chile 100.00% Uruguay 100.00% Uruguay 100.00% Mexico 100.00% Brazil 100.00% Chile 39.22% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Brazil 100.00% Chile 100.00% Chile 100.00% Cayman Islands 100.00% Brazil 100.00% Cayman Islands 100.00% Uruguay 100.00% Brazil 52.96% (1) The institutions operate in their respective countries of origin. (2) Current denomination of Linear Comercializadora de Energia Ltda. The institutions presented in the tables above represent the total scope of companies of Itaú Unibanco Conglomerate. Non Consolidated Institutions Non consolidated Institutions Country (1) % Equity share on capital BSF Holding S.A. Brazil 49.00% Compañia Uruguaya de Medios de Procesamiento S.A. Uruguay 31.47% Conectcar Soluções de Mobilidade Eletrônica S.A. Brazil 50.00% Gestora de Inteligência de Crédito S.A. Brazil 20.00% Kinea Private Equity Investimentos S.A. Brazil 80.00% Olímpia Promoção e Serviços S.A. Brazil 50.00% Porto Seguro Itaú Unibanco Participações S.A. Brazil 42.93% Pravaler S.A. Brazil 52.65% Rias Redbanc S.A Uruguay 25.00% Tecnologia Bancária S.A. Brazil 28.05% XP Inc. Cayman Islands 41.00% (1) The institutions operate in their respective countries of origin. 14 Itaú Unibanco

Risk and Capital Management - Pillar 3 Material entities Total assets, stockholders' equity, country and the activities of the material entities that are not consolidated in the regulatory scope, are as follows: R$ million 03/31/2021 12/31/2020 Institutions Country Activity Total Assets Equity Total Assets Equity Cia. Itaú de Capitalização 3,912 398 3,982 398 Brazil Premium bonds Itaú Consultoria de Valores Mobiliários e Participações S.A. 2,321 2,270 2,257 2,188 Brazil Financial institution holding company Itaú Corretora de Seguros S.A. 2,661 1,974 2,607 1,874 Brazil Insurance, pension plans and health brokers Itaú International Holding Limited 4 4 5 4 United Kingdom Holding Itaú Seguros S.A. 6,057 1,866 6,138 1,909 Brazil Insurance Itaú Vida e Previdência S.A. 217,210 2,949 220,652 3,182 Brazil Pension plan Itauseg Participações S.A. 10,695 10,690 10,955 10,902 Brazil Non financial institution holding company ITB Holding Brasil Participações Ltda. 30,115 29,354 29,365 27,146 Brazil Financial institution holding company Provar Negócios de Varejo Ltda. 2,524 2,474 2,520 2,468 Brazil Other auxiliary activities for financial services Composition of Capital CCA: Main features of regulatory capital instruments The authorized regulatory capital instruments may be extinguished according to the criteria established in Resolution No. 4,192 in articles 17, item XV, or 20, item X, such as non-compliance with the minimum regulatory ratios, decree of temporary special administration regime or intervention, application of public resources or upon the Central Bank of Brazil determination. Should any criteria for the extinction of subordinated instruments be triggered, the area responsible for Itaú Unibanco's Capital management will activate the areas involved to execute the following action plan: • The treasury, through the payment agent of the subordinated instruments or straight through the central depository, will notify its holders and take actions to ensure that Itaú Unibanco's trading desks cease to trade such instruments; • The operational and accounting areas will carry out the necessary procedures for the proper treatment of the extinction; and • The Investor Relations area will communicate the market of the extinction of the subordinated instruments. The table CCA-Main features of regulatory capital instruments, is available at www.itau.com.br/investor-relations, section 'Results and Reports', 'Regulatory Reports', 'Pillar 3'. 15 Itaú Unibanco

Risk and Capital Management - Pillar 3 CC1: Composition of regulatory capital 03/31/2021 Value Balance (R$ Thousand) Sheet Reference Common Equity Tier I: instruments and reserves 1 Instruments Eligible for the Common Equity Tier I 97,148,000 (k) 2 Revenue reserves 43,808,326 (l) 3 Other revenue and other reserve 51,156 (m) 5 Common share capital issued by subsidiaries and held by third parties (amount allowed in group CET1 capital) 11,325,274 (j) 6 Common Equity Tier I before regulatory adjustments 152,332,756 Common Equity Tier I: prudential adjustments 7 Prudential adjustments related to the pricing of financial instruments 275,754 8 Goodwill (net of related tax liability) 4,827,353 (e) 9 Intangible assets 9,379,601 (h) / (i) 10 Tax credits arising from income tax losses and social contribution tax loss carryfowards and those originating from this contribution related to determination periods ended until December 31, 1998 4,394,573 (b) Adjustments related to the market value of derivative financial instruments used to hedge the cash flows of 11 (272,776) protected items whose mark-to-market adjustments are not recorded in the books. 15 Actuarial assets related to defined benefit pension funds-(d) 16 Shares or other instruments issued by the bank authorized to compose the Core Capital, acquired directly, 532,765 indirectly or synthetically (n) 17 Reciprocal cross-holdings in common equity-Total value of adjustments related to net non-significant investments in the Common Equity Tier I of companies 18 that are similar to non-consolidated financial institutions, insurance companies, reinsurance companies,-capitalization companies and sponsored pension fund entities Total value of adjustments related to net significant investments in the Common Equity Tier I of companies that are similar to non-consolidated financial institutions, insurance companies, reinsurance companies, 19 6,006,095 capitalization companies and sponsored pension fund entities, that exceeds 10% of the amount of the Common Equity Tier I, disregarding specific adjustments 21 Total value of adjustments related to tax credits arising from temporary differences that depend on the generation of income or future taxable income for their realization, above the limit of 10% of the Common-Equity Tier I, disregarding specific deductions 22 Amount that exceeds 15% of the Common Equity Tier I 6,164,737 Of which: arising from net investments in the Common Equity Tier I of companies that are similar to non- 23 consolidated financial institutions, insurance companies, reinsurance companies, capitalization companies 3,376,513 and open ended pension entities 25 Of which: arising from tax credits resulting from temporary differences that depend on the generation of 2,788,224 income or future taxable income for their realization 26 National specific regulatory adjustments-26.a Deferred permanent assets-(g) 26.b Investment in dependence, financial institution abroad or non-financial entity that is part of the conglomerate, with respect to which the Central Bank of Brazil does not have access to information, data-and documents 26.d Increase of unauthorized capital-26.e Excess of the amount adjusted of Common Equity Tier I-26.f Deposit to cover capital deficiency-26.g Amount of intangible assets established before Resolution No. 4,192 of 2013 comes into effect-(i) 26.h Excess of resources invested on permanent assets-26.i Total capital detached-26.j Other residual differences concerning the Common Equity Tier I calculation methodology for regulatory-27 Other residual differences related to the calculation of the Common Equity Tier I for regulatory purposes-28 Total regulatory deductions from the Common Equity Tier I 31,308,102 29 Common Equity Tier I 121,024,654 Additional Tier I Capital: instruments 30 Instruments eligible for the Additional Tier I Capital 18,397,061 31 Of which: classified as equity under applicable accounting standards-32 Of which: classified as liabilities under applicable accounting standards 18,397,061 33 Instruments authorized to compose the Additional Tier I Capital before Resolution No. 4,192 of 2013 comes-34 Additional Tier 1 instruments issued by subsidiaries and held by third parties (amount allowed in group additional Tier 1 capital) 130,641 35 Of which: instruments issued by subsidiaries before Resolution No. 4,192 of 2013 comes into effect-36 Additional Tier I Capital before regulatory adjustments 18,527,702 16 Itaú Unibanco

Risk and Capital Management - Pillar 3 Additional Tier I Capital: regulatory adjustments 37 Shares or other instruments issued by the bank authorized to compose the Additional Tier I Capital, acquired directly, indirectly or synthetically-38 Reciprocal cross-holdings in additional Tier 1 instruments-Total value of adjustments related to net non-significant investments in the Additional Tier I Capital of 39 institutions authorized to operate by the Central Bank of Brazil or by a financial institution abroad outside the-scope of regulatory consolidation Total value of adjustments related to net significant investments in the Additional Tier I Capital of institutions 40 authorized to operate by the Central Bank of Brazil or by a financial institution abroad outside the scope of-regulatory consolidation 41 National specific regulatory adjustments-41.b Non-controlling interest in Additional Tier I Capital-41.c Other residual differences concerning the Additional Tier I Capital calculation methodology for regulatory purposes-42 Regulatory adjustments applied to the Additional Tier I Capital due to the insufficient Tier II Capital to cover deductions-43 Total regulatory deductions from the Additional Tier I Capital-44 Additional Tier I Capital (AT1) 18,527,702 45 Tier I 139,552,356 Tier II: instruments 46 Instruments eligible for Tier II 11,697,657 47 Instruments that are authorized to compose Tier II before Resolution No. 4,192 of 2013 comes into effect 3,944,513 48 Tier 2 instruments issued by subsidiaries and held by third parties (amount allowed in group Tier 2) 85,708 49 Of which: instruments issued by subsidiaries before Resolution No. 4,192 of 2013 comes into effect-51 Tier II before regulatory adjustments 15,727,878 Tier II: regulatory adjustments 52 Shares or other instruments issued by the bank authorized to compose Tier II, acquired directly, indirectly or synthetically-53 Reciprocal cross-holdings in Tier 2 instruments-Total value of adjustments related to net non-significant investments in the Tier II and other TLAC liabilities of-54 institutions authorized to operate by the Central Bank of Brazil or by a financial institution abroad outside the scope of regulatory consolidation 55 Total value of adjustments related to net significant investments in the Tier II and other TLAC liabilities of-institutions authorized to operate by the Central Bank of Brazil or by a financial institution abroad outside the scope of regulatory consolidation 56 National specific regulatory adjustments-56.b Non-controlling interest in Tier II-56.c Other residual differences concerning Tier II calculation methodology for regulatory purposes-57 Total regulatory deductions from Tier II Capital-58 Tier II 15,727,878 59 Referential Equity (Tier I + Tier II) 155,280,234 60 Total risk-weighted assets 1,072,192,783 BIS Ratios and Additional Capital Buffers 61 Common Equity Tier I Ratio 11.3% 62 Tier I Ratio 13.0% 63 BIS Ratio 14.5% 64 Additional Capital Buffers (% of RWA) 2.25% 65 Of which: capital conservation buffer requirement 1.25% 66 Of which: bank-specific countercyclical buffer requirement 0.0% 67 Of which: capital buffer for institutions that are systemically important at global level (G-SIB) 1.0% 68 Common Equity Tier 1 capital available after meeting the bank's minimum capital requirements (% of RWA) 4.1% Amounts below the limit for deduction (non-weighted by risk) Total value, subject to risk weighting, of non-significant investments in the Common Equity Tier I of institutions authorized to operate by the Central Bank of Brazil, non-consolidated overseas financial institutions, companies that are similar to non-consolidated financial institutions, insurance companies, reinsurance companies, 72 1,131,163 capitalization companies and open ended pension entities, as well as non-significant investments in the Additional Tier I, Tier II and other TLAC liabilities of institutions authorized to operate by the Central Bank of Brazil or by a financial institution abroad outside the scope of regulatory consolidation Total value, subject to risk weighting, of significant investments in the Common Equity Tier I of institutions authorized to operate by the Central Bank of Brazil, non-consolidated overseas financial institutions, companies 73 9,943,035 (f) / (a) that are similar to non-consolidated financial institutions, insurance companies, reinsurance companies, capitalization companies and sponsored pension fund entities 75 Tax credits arising from temporary differences, not deducted from the Common Equity Tier I 20,714,355 (c) Instruments authorized to compose the Referential Equity before Resolution No. 4,192 of 2013 comes into effect (applicable between October 1, 2013 and January 1, 2022) Instruments that are authorized to compose the Additional Tier I Capital before Resolution No. 4,192 of 2013-82 comes into effect 83 Amount excluded from the Additional Tier I Capital due to the line 82 limit-84 Instruments that are authorized to compose Tier II before Resolution No. 4,192 of 2013 comes into effect 3,944,513 85 Amount excluded from Tier II due to the line 84 limit 35,500,614 17 Itaú Unibanco

Risk and Capital Management - Pillar 3 CC2: Reconciliation of regulatory capital to balance sheet R$ million, at the end of the period 03/31/2021 Balance Sheet as in Under regulatory Consolidated Balance Sheet (1) published financial scope of Reference (2) statements consolidation Assets Current assets and Long-term receivables 2,087,728 1,857,593 Cash 39,369 39,285 Interbank investments 252,251 251,125 Securities and derivative financial instruments 734,593 510,000 Interbank accounts 137,254 137,255 Interbranch accounts 322 322 Loan, lease and other credit operations 687,447 688,302 Other receivables 233,326 228,220 Deferred tax assets-63,723 (b) / (c) Sundry-164,497 (b) / (d) Other assets 3,166 3,085 Permanent assets 37,089 59,530 Investments 16,517 40,259 (a) / (e) / (f) Real estate 6,405 5,915 Goodwill and Intangible assets 14,167 13,356 Goodwill-3,872 (e) Intangible assets-9,380 (h) / (i) Other-104 Total assets 2,124,817 1,917,123 Liabilities Current and Long-term Liabilities 1,969,123 1,761,372 Deposits 821,379 826,548 Deposits received under securities repurchase agreements 261,774 265,329 Funds from acceptances and issuance of securities 140,351 140,351 Interbank accounts 52,518 52,518 Interbranch accounts 9,094 9,098 Borrowings and onlending 88,393 88,393 Derivative financial instruments 73,615 73,201 Technical provision for insurance, pension plan and capitalization 220,441-Provisions 17,137 16,714 Allowance for financial guarantees provided 802 802 Other liabilities 283,619 288,418 Deferred tax liabilities-3,198 (b) / (c) Sundry-285,220 (d) Deferred income 3,346 3,378 Non-controlling interest in subsidiaries 11,979 11,898 (j) Stockholders' equity 140,369 140,475 Capital 97,148 97,148 (k) Other Revenues and Other Reserves (1,199) 51 (m) Revenue reserves 44,953 43,808 (l) (Treasury shares) (533) (533) (n) Total liabilities and stockholders' equity 2,124,817 1,917,123 (1) Differences are mainly due to non-consolidation of non financial companies (highlighting the following companies: Insurance, Pension Plan and Premium Bonds) within the Prudencial Conglomerate and also by the eliminations of transactions with related parties. (2) Prudential information that is presented in the Template CC1 of this document. 18 Itaú Unibanco

Risk and Capital Management - Pillar 3 Macroprudential Indicators CCyB1: Geographical distribution of credit risk exposures considered in the calculation of the Countercyclical Capital Buffer The following table details the geographic distribution of credit risk exposures considered in the calculation of the Countercyclical Capital Buffer, according to Circular 3,769 of 29 October 2015: R$ million 03/31/2021 Exposure values and/or risk- weighted assets (RWA) used in the computation of the countercyclical capital Bank-specific Countercyclical Countercyclical buffer Geographical breakdown countercyclical capital buffer capital buffer rate Amount of credit risk capital buffer rate amount (3) exposure to the non-banking RWACPrNB private sector Brazil-1,368,872 570,715-Luxembourg 0.50% 1,833 1,176-Norway 1.00% 365 248-Hong Kong 1.00% 120 120-Sum(1) 1,371,190 572,259 Total(2) 1,726,779 817,270 - (1) Sum of RWACPrNBi portions related to credit risk exposures to the non-banking private sector in Brazil and jurisdictions with a percentage of the countercyclical buffer with values greater than zero. (2) Total of RWA for non-bank private credit risk exposures to all jurisdictions in which the bank has exposure, including jurisdictions with no countercyclical buffer percentage applied or with a countercyclical percentage equal to zero. (3) Calculated according to Circular 3.769, employing the discretionary exclusion of jurisdiction. GSIB1: Disclosure of G-SIB indicators The GSIB1 table, disclosure of global systemically important bank (G-SIB) indicators, will be available on the website www.itau.com.br/investor-relations, section 'Results and Reports', 'Regulatory Reports', 'Pillar 3', within the period stipulated by BACEN Circular 3.751/15. 19 Itaú Unibanco

Risk and Capital Management - Pillar 3 Leverage Ratio The Leverage Ratio is defined as the ratio between Tier I Capital and Total Exposure, calculated according to BACEN Circular 3,748. The ratio is intended to be a simple measure of non-risk-sensitive leverage, and so it does not take into account risk weights or risk mitigation. As required by BACEN Circular Letter 3,706, Itaú Unibanco monthly reports to BACEN the Leverage Ratio, which minimum requirement is of 3%. The following information is based on the methodology and standard format introduced by BACEN Circular 3,748. LR1: Summary comparison of accounting assets vs leverage ratio exposure measure (RA) R$ million 03/31/2021 12/31/2020 Total consolidated assets as published financial statements 2,124,817 2,112,586 Adjustment from differences of consolidation (207,694) (210,852) Total assets of the individual balance sheet or of the regulatory consolidation, in the case of Leverage Ratio on a 1,917,123 1,901,734 consolidated basis Adjustments for derivative financial instruments 27,259 21,996 Adjustment for securities financing transactions (ie repos and similar secured lending) 15,668 17,004 Adjustment for off-balance sheet items (ie conversion to credit equivalent amounts of off-balance sheet exposures) 138,588 128,409 Other adjustments (180,407) (165,845) Total Exposure 1,918,231 1,903,298 LR2: Leverage ratio common disclosure R$ million 03/31/2021 12/31/2020 Items shown in the Balance Sheet Balance sheet items except derivative financial instruments, securities received on loan and resales for settlement 1,541,514 1,472,209 under repurchase transactions Adjustments for equity items deducted in the calculation of Tier I (38,263) (35,246) Total exposure shown in the Balance Sheet 1,503,251 1,436,963 Transactions using Derivative Financial Instruments Replacement value for derivatives transactions 35,580 39,619 Potential future gains from derivatives transactions 13,426 12,010 Adjustment for collateral in derivatives transactions - Adjustment related to the deduction of the exposure because of the qualified central counterparty (QCCP) in derivative transactions on behalf of clients in which there is no contractual obligation to reimburse due to bankruptcy (6,838) (5,502) or default of the entities responsible for the settlement and compensation of transactions Reference value for credit derivatives 22,195 16,355 Adjustment of reference value calculated for credit derivatives (3,996) (2,294) Total exposure for derivative financial instruments 60,367 60,188 Repurchase Transactions and Securities Lending (TVM) Investments in repurchase transactions and securities lending 178,058 237,669 Adjustment for repurchases for settlement and creditors of securities lending - Amount of counterparty credit risk 15,667 17,005 Amount of counterparty credit risk in transactions as intermediary 22,300 23,064 Total exposure for repurchase transactions and securities lending 216,025 277,738 Off-balance sheet items Reference value of off-balance sheet transactions 427,756 394,021 Adjustment for application of FCC specific to off-balance sheet transactions (289,168) (265,612) Total off-balance sheet exposure 138,588 128,409 Capital and Total Exposure Tier I 139,552 137,157 Total Exposure 1,918,231 1,903,298 Leverage Ratio Basel III Leverage Ratio 7.3% 7.2% 20 Itaú Unibanco

Risk and Capital Management - Pillar 3 Liquidity Ratios LIQA: Liquidity Risk Management Information Framework and Treatment Liquidity risk is defined as the likelihood of the institution not being able to effectively honor its expected and unexpected obligations, current and future, including those from guarantees commitment, without affecting its daily operations or incurring in significant losses. In line with the fundraising strategy, Itaú Unibanco has diversified and stable sources of funding available, monitored through concentration and maturity indicators, in order to mitigate liquidity risks, in accordance with the institution's risk appetite. The governance of the liquidity risk management is based on advisory boards, subordinated to the Board of Directors or the executive structure of Itaú Unibanco. Such boards establish the institution's risk appetites, define the limits related to the liquidity control and monitor the liquidity indicators. The control of the liquidity risk is carried out by an area that is independent of the business areas, responsible for defining the composition of the reserve, estimating the cash flow and the exposure to liquidity risk in different time horizons and monitoring short and long term liquidity indicators (LCR and NSFR respectively). In addition, it proposes minimum limits to absorb losses in stress scenarios for each country where Itaú Unibanco operates and reports any non-compliance to the competent authorities. All activities are subject to verification by the independent validation, internal controls and audit departments. Additionally, and pursuant to the requirements of Resolution 4,557, BACEN Circular 3,749 and Circular 3,869, the Liquidity Risk Statement (DRL-LCR) and the Long Term Liquidity Statement (DLP-NSFR) are monthly sent to BACEN. Finally, the following items are periodically prepared and submitted to senior management for monitoring and decision support: • Stress of liquidity indicators based on macroeconomic scenarios, simulation of reverse stress based on risk appetite, and projection of the main liquidity indicators to support decisions; • Contingency and recovery plans for crisis situations, with actions that provide for a gradation according to the level of criticality determined by the easiness of implementation, taking into account the characteristics of the local market in which it operates, seeking a rapid restoration of liquidity indicators; • Reports and graphs that describe risk positions; • Concentration indicators of funding providers and time. The document that details the liquidity risk control institutional policy is on the Investor Relations website https://www.itau.com.br/investor-relations, section 'Itaú Unibanco', under 'Corporate Governance', 'Rules and Policies', 'Reports'. 21 Itaú Unibanco

Risk and Capital Management - Pillar 3 LIQ1: Liquidity Coverage Ratio (LCR) 03/31/2021 (1) 12/31/2020 (1) Total unweighted Total unweighted Total weighted value Total weighted value value value (In thousand R$)(3) (In thousand R$)(3) (In thousand R$)(2) (In thousand R$)(2) High Quality Liquidity Assets (HQLA) Total High Quality Liquid Assets (HQLA) 356,221,955 343,173,952 Cash Outflows (4) Retail deposits and deposits from small business customers, of which: 437,630,944 38,379,043 419,224,248 36,640,083 Stable deposits 225,272,797 11,263,640 219,508,612 10,975,431 Less stable deposits 212,358,147 27,115,403 199,715,636 25,664,652 Unsecured wholesale funding, of which: : 312,048,042 137,819,582 304,576,741 133,902,894 Operational deposits (all counterparties) and deposits in networks of cooperative banks 1,087,942 54,397 1,087,943 54,397 Non-operational deposits (all counterparties) 308,830,829 135,635,914 302,083,965 132,443,664 Unsecured debt 2,129,271 2,129,271 1,404,833 1,404,833 Secured wholesale funding 19,532,903 19,500,532 Additional requirements, of which: 263,405,481 32,865,519 263,380,052 34,711,729 Outflows related to derivative exposures and other collateral requirements 36,302,252 16,996,734 45,560,951 19,837,130 Outflows related to loss of funding on debt products 1,081,317 1,081,317 899,898 899,898 Credit and liquidity facilities 226,021,912 14,787,468 216,919,203 13,974,701 Other contractual funding obligations 71,657,640 71,657,640 67,084,973 67,084,973 Other contingent funding obligations 127,602,820 22,194,867 126,795,864 17,811,618 Total Cash Outflows 322,449,554 309,651,829 Cash Inflows (4) Secured lending (eg reverse repos) 186,142,060 1,237,499 224,849,423 1,834,771 Inflows from fully performing exposures 35,767,315 22,824,152 31,230,277 19,581,578 Other cash inflows 126,163,864 111,875,114 124,631,499 111,880,233 Total Cash Inflows 348,073,239 135,936,765 380,711,199 133,296,582 Total Adjusted Total Adjusted Value(5) Value(5) Total HQLA 356,221,955 343,173,952 Total net cash outflows 186,512,789 176,355,247 Liquidity Coverage Ratio (%) 191.0% 194.6% (1) Corresponds to 61 daily average observations at 1Q21 and 63 daily at 4Q20 (2) Total balance off the cash inflows or outflows (3) After aplication of weighting factors (4) Potential cash outflows (Outflows e) and inflows (inflows e) (5) Amount calculated after applying weighting factors and limits set by BACEN Circular 3,749 Itaú Unibanco has High Quality Liquidity Assets (HQLA) that amounted to R$ 356.2 billion on average for the quarter, mainly composed of Sovereign Securities, Central Bank Reserves and Cash. Net Cash Outflows amounted to R$ 186.5 billion on average for the quarter, which are mostly comprised of Retail Funding, Wholesale, Additional Requirements, Contractual and Contingent Obligations, offset by Cash inflows from loans and other Cash inflows. The table shows that the average LCR in the quarter is191.0%, above the limit of 100%, and therefore the institution has high quality liquidity resources comfortably available to support the losses in the standardized stress scenario for the LCR. 22 Itaú Unibanco

Risk and Capital Management - Pillar 3 LIQ2: Net Stable Funding Ratio (NSFR) Value per residual effective maturity term (R$ thousand) Greater than or equal to Lower than six Greater than or equal Weighted Value (2) 03/31/2021 No Maturity (1) (1) six months, and lower months (1) to 1 year (1) (In thousand R$) than 1 year Available Stable Funding (ASF) (3) Capital --207,096,653 207,096,653 Reference Equity, gross of regulatory deductions --152,645,725 152,645,725 Other capital instruments not included in line 2 --54,450,928 54,450,928 Retail Funding: 205,705,911 255,824,340 4,040,628 19,084,199 449,558,771 Stable Funding 125,068,921 103,908,605 238,105 217,951 217,972,800 Less Stable Funding 80,636,990 151,915,735 3,802,523 18,866,248 231,585,971 Wholesale Funding: 69,260,238 580,540,546 72,233,586 127,063,464 329,751,410 Operational deposits and deposits of member cooperatives 4,424,956 --2,212,477 Other Wholesale Funding 64,835,282 580,540,546 72,233,586 127,063,464 327,538,933 Opertions in which the institution acts exclusively as intermediary, not undertaking any rights or obligations, even if-72,620,871 8,679,913 696,444-contingent Other liabilities, in which: 91,434,502 138,990,116 34,218 3,773,266 3,790,375 Derivatives whose replacement values are lower than zero 20,571,558 - Other liability or equity elements not included above 91,434,502 118,418,558 34,218 3,773,266 3,790,375 Total Available Stable Funding (ASF) 990,197,209 Required Stable Funding (RSF) (3) Total NSFR high quality liquid assets (HQLA) 22,752,392 Operational deposits held at other financial institutions - --Performing loans and securities (financial institutions, 3,445,123 386,342,233 93,681,105 456,310,754 538,775,655 corporates and central banks) Performing loans to financial institutions secured by Level 1 HQLA-44,068,267-135,446 4,542,273 Performing loans to financial institutions secured by non-Level 1 3,202,956 37,725,467 3,163,972 29,210,422 37,132,110 HQLA and unsecured performing loans to financial institutions Performing loans to non-financial corporate clients, loans to retail and small business customers, and loans to sovereigns, central 242,167 267,734,548 71,430,591 261,018,347 335,789,072 banks, of which: With a risk weight of less than or equal to 35%, approach for --4,439,940 2,885,961 credit risk, according to Circular 3,644. Performing residential mortgages, of which:-15,471,808 12,985,989 74,933,346 69,942,476 Which are in accordance to Circular 3,644, 2013, art. 22 --55,892,519 41,761,381 Securities that are not in default and do not qualify as HQLA,-21,342,143 6,100,553 91,013,193 91,369,724 including exchange-traded equities Operations in which the institution acts exclusively as intermediary, not undertaking any rights or obligations, even if-79,360,113 8,027,975 1,144,043-contingent Other assets, in which: 82,125,032 166,444,299 9,425,203 101,350,572 211,549,054 Transactions with gold and commodities, including those with - expected physical settlement Assets posted as initial margin for derivatives contracts and participation in mutual guarantee funds of clearinghouses or - 26,807,984 22,786,787 providers of clearing and settlement services which acts as central counterparty. Derivatives whose replacement values are higher than or equal to 18,400,290-2,256,442 2,256,442 Derivatives whose replacement values are less than zero, gross of the deduction of any collateral provided as a result of deposit of - 1,169,495 1,169,495 variation margin All other assets not included in the above categories 82,125,032 148,044,009 9,425,203 71,116,651 185,336,330 Off-balance sheet transactions 473,055,384 7,621,780 19,121,555 Total Required Stable Funding (RSF) 792,198,656 NSFR (%) 125.0% (1) Corresponds to the total amount of Available Stable Funding (ASF) or Required Stable funding (RSF). (2) Corresponds to the amount after application of weighting factors. (3) Corresponds to the Available Stable Funding (ASF) or Required Stable Funding (RSF). Total Adjusted Value Total Adjusted Value R$ thousand 03/31/2021 (1) 12/31/2020 (1) Total Available Stable Funding (ASF) 990,197,209 956,032,752 Total Required Stable Funding (RSF) 792,198,656 758,907,175 NSFR (%) 125.0% 126.0% (1) Corresponds to the amount calculated after application of the weighting factors and limits set forth in BACEN Circular 3,869. Itaú Unibanco has an Available Stable Funding (ASF) amounted to R$ 990.2 billion in the first quarter, mainly composed of Capital, Retail Funding and Wholesale. In addition, the Required Stable Funding (RSF) amounted to R$ 792.2 billion in the first quarter, which are mostly composed of loans and financing granted to wholesale, retail, central economies and central bank operations. The table shows that the NSFR at the end of the quarter is 125.0%, above the limit of 100%, and therefore the institution has Available Stable Funding to support the Required Stable Funding comfortably in the long-term, according to the metric. 23 Itaú Unibanco

Risk and Capital Management - Pillar 3 Credit Risk CRA: Qualitative information on credit risk management Itaú Unibanco defines credit risk as the risk of loss associated with: failure by a borrower, issuer or counterparty to fulfill their respective financial obligations as defined in the contracts; value loss of credit agreements resulting from deterioration of the borrower's, issuer's or counterparty's credit rating; reduction of profits or income; benefits granted upon subsequent renegotiations; or debt recovery costs. The management of credit risk is intended to preserve the quality of the loan portfolio at levels compatible with the institution's risk appetite for each market segment in which Itaú Unibanco operates. The governance of credit risk is managed through corporate bodies, which report to the Board of Directors or to the Itaú Unibanco executive structure. Such corporate bodies act primarily by assessing the competitive market conditions, setting the credit limits for the institution, reviewing control practices and policies, and approving these actions at the respective authority levels. The risk communication and reporting process, including disclosure of institutional and supplementary policies on credit risk management, are also function of this structure. Itaú Unibanco manages the credit risk to which it is exposed during the entire credit cycle, from before approval, during the monitoring process and up to the collection or recovery phase. There is a credit risk management and control structure, centralized and independent of the business units which defines operational limits, risk mitigation mechanisms and processes, and instruments to measure, monitor and control the credit risk inherent to all products, portfolio concentrations and impacts to potential changes in the economic environment. Such structure is subjected to internal and external auditing processes. The credit's portfolio, policies and strategies are continuously monitored so as to ensure compliance with the rules and laws in effect in each country. The key assignments of the business units are (i) monitoring of the portfolios under their responsibility, (ii) granting of credit, taking into account current approval levels, market conditions, the macroeconomic prospects and changes in markets and products, and (iii) credit risk management aimed at making the business sustainable. Itaú Unibanco's credit policy is based on internal factors, such as: client rating criteria, performance and evolution of the portfolio, default levels, return rates and allocated economic capital, among others; and also take into account external factors such as: interest rates, market default indicators, inflation and changes in consumption, among others. With respect to individuals, small and medium companies, credit ratings are assigned based on statistical application (in the early stages of relationship with a customer) and behavior score (used for customers with whom Itaú Unibanco already has a relationship) models. For large companies, classification is based on information such as the counterparty's economic and financial situation, its cash-generating capacity, and the business group to which it belongs, the current and prospective situation of the economic sector in which it operates. Credit proposals are analyzed on a case-by-case basis through the approval governance. The concentrations are monitored continuously for economic sectors and largest debtors, allowing preventive measures to be taken to avoid the violation of the established limits. Itaú Unibanco also strictly controls credit exposure to clients and counterparties, acting to reverse occasional limit breaches. In this sense, contractual covenants may be used, such as the right to demand early payment or require additional collateral. To measure credit risk, Itaú Unibanco takes into account the probability of default by the borrower, issuer or counterparty, the estimated amount of exposure in the event of default, past losses from default and concentration of borrowers. Quantifying these risk components is part of the lending process, portfolio management and definition of limits. The models used by Itaú Unibanco are independently validated, to ensure that the databases used in constructing the models are complete and accurate, and that the method of estimating parameters is adequate. Itaú Unibanco counts on a specific structure and processes aimed at ensuring that the country risk is managed and controlled, described in item 'Other Risks'. 24 Itaú Unibanco

Risk and Capital Management - Pillar 3 In compliance with CMN Resolution 4,557, the document 'Public Access Report-Credit Risk,' which describes the guidelines established in the institutional ruling on credit risk control, can be viewed on the website www.itau.com.br/investor-relations, section 'Itaú Unibanco', under 'Corporate Governance', 'Rules and Policies', 'Reports'. CR1: Credit Quality of Assets R$ million 03/31/2021 Gross carrying values of Allowances, Unearned Revenues and ECL Defaulted Non- defaulted Net values (a+b-c) accounting provision exposures (a) exposures (b) (c) Loans 24,737 819,527 131,370 712,894 Debt Securities 295 429,778 5,047 425,026 in which: Sovereigns-275,489 647 274,842 in which: Other Debts 295 154,289 4,400 150,184 Off-balance sheet exposures-424,100 802 423,298 Total 25,032 1,673,405 137,219 1,561,218 CR2: Changes in Stock of defaulted loans and debts securities R$ million Total Defaulted loans and debt securities at end of the previous reporting period (12/31/2020) 23,982 Loans and debt securities that have defaulted since the last reporting period 9,938 Amount returned to non-defaulted status (537) Amount written off (7,105) Other changes (1,246) Defaulted loans and debt securities at end of the reporting period (03/31/2021) 25,032 CRB: Additional disclosure related to the credit quality of assets The tables below contain additional disclosure related to the credit quality exposures reported in the table CR1. In these tables are informed the breakdown of exposures by geographical area, industry and defaulted exposures. In addition, the total overdue exposures segregated by residual maturity, the total restructured exposures and the percentage of the ten and one hundred largest exposures are also reported. 25 Itaú Unibanco

Risk and Capital Management - Pillar 3 Exposure by industry Total Exposure Total defaulted loans and debt securities R$ million 03/31/2021 R$ million 03/31/2021 Portfolio Portfolio Total Exposure Total Exposure Defaulted Expected (Net values) (Gross values) Exposures Credit Loss Companies 972,155 1,014,564 Companies 7,400 3,456 Public sector 338,473 339,380 Public sector - Energy 2,562 2,562 Energy - Petrochemical and Chemical 3,441 3,532 Petrochemical and Chemical - Sundry 332,470 333,286 Sundry - Private sector 633,682 675,184 Private sector 7,400 3,456 Sugar and Alcohol 9,369 9,869 Sugar and Alcohol 49 (12) Agribusiness and Fertilizers 28,663 29,551 Agribusiness and Fertilizers 148 93 Food and Beverage 30,528 31,762 Food and Beverage 292 136 Banks and Other Financial Institutions 63,352 64,028 Banks and Other Financial Institutions 39 29 Capital Assets 9,784 10,280 Capital Assets 79 47 Pulp and Paper 4,120 4,219 Pulp and Paper 10 6 Electronic and IT 14,859 15,582 Electronic and IT 206 21 Packaging 5,065 5,316 Packaging 7 4 Energy and Sewage 39,473 39,785 Energy and Sewage 9-Education 6,649 7,056 Education 97 54 Pharmaceuticals and Cosmetics 17,898 18,425 Pharmaceuticals and Cosmetics 141 64 Real Estate Agents 44,300 47,505 Real Estate Agents 604 426 Entertainment and Tourism 11,774 14,328 Entertainment and Tourism 749 345 Wood and Furniture 7,030 7,669 Wood and Furniture 157 97 Construction Material 8,732 9,430 Construction Material 112 49 Steel and Metallurgy 13,349 14,122 Steel and Metallurgy 218 9 Media 1,264 1,305 Media 7 2 Mining 9,902 10,246 Mining 15 13 Infrastructure Work 15,187 16,100 Infrastructure Work 101 68 Oil and Gas 13,377 13,975 Oil and Gas 99 43 Petrochemical and Chemical 18,532 19,038 Petrochemical and Chemical 66 34 Health Care 10,356 10,823 Health Care 40 18 Insurance and Reinsurance and Pension Plans 149 152 Insurance and Reinsurance and Pension Plans - Telecommunications 9,825 10,056 Telecommunications 37 29 Clothing and Footwear 6,700 7,493 Clothing and Footwear 231 130 Trading 3,930 4,095 Trading 100 77 Transportation 35,453 38,016 Transportation 248 130 Domestic Appliances 4,221 4,307 Domestic Appliances 22 9 Vehicles and Autoparts 24,732 26,035 Vehicles and Autoparts 263 116 Third Sector 3,798 3,849 Third Sector 1-Publishing and Printing 2,837 3,221 Publishing and Printing 121 51 Commerce-Sundry 45,658 49,076 Commerce-Sundry 1,056 540 Industry-Sundry 13,141 13,278 Industry-Sundry 22 12 Sundry Services 62,943 72,242 Sundry Services 1,265 735 Sundry 36,732 42,950 Sundry 789 81 Individuals 589,063 683,873 Individuals 17,632 9,003 Total 1,561,218 1,698,437 Total 25,032 12,459 Exposure by remaining maturity R$ million 03/31/2021 R$ million 03/31/2021 Remaining maturities of transactions Remaining maturities of transactions (Net values) (1) (Gross values) (1) up to 6 months 6 to 12 months 1 to 5 years above 5 years Total up to 6 months 6 to 12 months 1 to 5 years above 5 years Total 375,498 78,426 461,032 297,357 1,212,313 402,623 82,652 520,530 343,539 1,349,344 (1) Do not consider the amount of credits to be released. Overdue exposures R$ million 03/31/2021 . Gross Portfolio Overdue amounts (1) Less than 30 days 7,939 31 to 90 days 11,171 91 to 180 days 10,935 181 to 365 days 12,503 above 365 days 1,594 Total 44,141 (1) According to Circular Letter 4,068, the table follows the same scope as table CR1. 26 Itaú Unibanco

Risk and Capital Management - Pillar 3 Exposure by geographical area in Brazil and by country Total Exposure Total defaulted loans and debt securities R$ million 03/31/2021 R$ million 03/31/2021 Portfolio Portfolio Total Exposure Total Exposure Defaulted Expected Credit (Net values) (Gross values) exposures Loss Southeast 669,305 745,661 Southeast 13,910 6,376 South 100,944 115,058 South 2,522 1,219 North 17,523 22,280 North 655 319 Northeast 83,206 98,922 Northeast 3,188 1,722 Midwest 47,327 54,768 Midwest 1,411 686 National territory1 1,091,702 1,206,772 National territory1 21,391 10,525 Brazil 1,193,147 1,312,143 Brazil 21,686 10,322 Argentina 6,525 6,980 Argentina 57 38 Chile 196,099 202,926 Chile 2,524 1,494 Colombia 46,440 55,809 Colombia 576 450 United States 24,543 24,851 United States - Paraguay 16,934 17,247 Paraguay 104 85 United Kingdom 19,120 19,353 United Kingdom - Swiss 3,701 3,701 Swiss - Uruguay 23,475 23,831 Uruguay 77 62 Other 31,234 31,596 Other 8 8 Foreign 368,071 386,294 Foreign 3,346 2,137 Total 1,561,218 1,698,437 Total 25,032 12,459 (1) Considers Brazilian treasury bonds. Largest debtors exposures R$ million 03/31/2021 Loans, Debt Securities and Off-balance sheet exposures (CR1)(1) Exposure % of portfolio 10 largest debtors 345,513 22.3% 100 largest debtors 483,113 31.2% (1) According to Circular Letter 4,068, the table follows the same scope as table CR1, in which the exposure value considers sovereign debt securities. Restructured exposures R$ million 03/31/2021 Overdue Others Restructured Exposures 5,136 19,267 27 Itaú Unibanco

Risk and Capital Management - Pillar 3 CRC: Qualitative disclosure related to Credit Risk Mitigation techniques Itaú Unibanco uses guarantees to increase its recovery capacity in operations subject to credit risk. The guarantees used can be personal, real, legal structures with mitigating power and offsetting agreements. For guarantees to be considered as credit risk mitigating instruments, they must comply with the requirements and rules that regulate them, whether internal or external, and they must be legally exercisable (effective), enforceable and regularly evaluated. For real guarantees, legal structures with mitigating power and offsetting agreements, the mitigation is based on methodologies established and approved by the business units responsible for the management of credit risk and the centralized area of credit risk control. Such methodologies consider factors related to the legal enforceability of guarantees, the necessary costs and the expected value in the execution, taking into account the volatility and liquidity of the market. Additionally, the concentration of these instruments in the loan portfolio is regularly monitored. Itaú Unibanco also uses credit derivatives to mitigate the credit risk of its securities portfolios. These instruments are priced based on models that use the fair price of market variables, such as credit spreads, recovery rates, correlations and interest rates. The information related to the possible concentration associated with credit risk mitigation considers different mitigating instruments, segregating by type and by provider. For reasons of confidentiality, the institution determines the non-disclosure of information beyond the classification of the type of guarantor, but ensuring adherence to general requirements. Regarding to real guarantees, it is segregated by type: • Financial collaterals • Bilateral contracts • Assets Regarding to personal guarantees, it is segregated by provider: • Legal entities (Public and private companies) • Multilateral Development Entities (EMD) • Financial Institution • Sovereigns • National Treasury or Central Bank Regarding derivatives, it is segregated by provider: • Legal entities • Multilateral Development Entities (EMD) • Financial Institution • Sovereigns CR3: Credit Risk mitigation techniques - overview (1) R$ million 03/31/2021 Exposures Exposures Exposures Unsecured Secured secured by secured by secured by Exposures Exposures financial collateral credit derivatives guarantees Loans 630,245 75,518 7,261 68,257-Debt securities 416,826 246 246 - Off-balance sheet exposures 129,955 4,041 479 3,562-Other Exposures 361,863 5,240 5,240 - Total 1,538,889 85,045 13,226 71,819-Of which defaulted 5,199 522 1 521-(1) The mitigating instruments contemplated in this table are those foreseen in BACEN Circular 3,809. 28 Itaú Unibanco

Risk and Capital Management - Pillar 3 Increase in credit granting observed in retail, corporate and mortgage loans. In debt securities, the main variation comes from exposures to governments and central banks. CR4: Standardized Approach - Credit Risk exposure and credit risk mitigation effects R$ million 03/31/2021 Exposures before CCF and CRM Exposures post-CCF and CRM RWA and RWA density On- balance Off- balance On- balance Off- balance Off- balance Asset classes RWA (e) sheet amount sheet amount (a) sheet amount (b) sheet amount (c) sheet amount (d) [e/(c+d)] Sovereigns and their central banks 531,242-531,242-15,546 3% Non-central government public sector entities 4,941 78 4,941 39 3,900 78% Multilateral development banks 320-320 - 0% Banks and other Financial Institutions authorized by Brazil Central Bank 116,152 4,033 116,152 1,591 40,981 35% Corporates 382,674 118,330 382,674 65,771 399,375 89% Regulatory retail portfolios 257,372 295,483 257,372 62,527 220,241 69% Secured by residential property 91,760 2,649 91,760 2,649 33,979 36% Secured by commercial real estate 184 259 184 259 221 50% Equity stake 23,826-23,826-23,274 98% Other assets 81,467 2,332 81,467 1,160 82,507 100% Total 1,489,938 423,164 1,489,938 133,996 820,024 50% CR5: Standardized Approach - exposures by asset classes and risk weights R$ million Risk weight (FPR) 03/31/2021 Total credit exposures Asset classes 0% 10% 20% 35% 50% 75% 85% 100% Others amount (post CCF and post- CRM) Sovereigns and their central banks 507,180-172-18,559 - 3,526 1,805 531,242 Non-central government public sector entities 184-23-523-4,109 141-4,980 Multilateral development banks 320 - - - - 320 Banks and other Financial Institutions authorized by Brazil Central Bank 2,048-56,759 3,067 54,626 - 1,243-117,743 Corporates 8,794 --15,574-214,879 208,579 619 448,445 Regulatory retail portfolios 8,839 --43,542 263,701 - 3,817 319,899 Secured by residential property --88,273 6,062 --74 94,409 Secured by commercial real estate - - 443 - - 443 Equity stake - - - 3,684 20,142-23,826 Other assets 120 - - - 82,507-82,627 Total 527,485-56,954 91,340 139,329 263,701 222,672 316,138 6,315 1,623,934 The increase in total exposures in tables CR4 and CR5 occurred mainly in the retail, corporates, mortgage loans and securities issued by governments and central banks. 29 Itaú Unibanco

Risk and Capital Management - Pillar 3 Counterparty Credit Risk (CCR) CCRA: Qualitative disclosure related to CCR Counterparty credit risk is the possibility of noncompliance with obligations related to the settlement of transactions that involve the trading of financial assets with a bilateral risk. It encompasses derivative financial instruments, settlement pending transactions, securities lending and repurchase transactions. Itaú Unibanco has well-defined rules for calculating its exposure to this risk, and the models designed are used both for controlling the use of counterparty limits and for allocating capital. For derivatives, Itaú Unibanco also uses the potential credit risk (PCR), interpreted as the value of the potential financial exposure that a transaction can attain upon maturity. The risk may be mitigated by the use of margin call, initial margin or other mitigating instrument. Currently, Itaú Unibanco does not have impact in the amount of collateral that the bank would be required to provide given a credit rating downgrade. The counterparty credit risk exposures are presented as follows. CCR1: Analysis of CCR exposures by approach R$ million 03/31/2021 Multiplier applied Replacement Potential future EAD to the calculation RWA cost exposure post mitigation of EAD SA-CCR Approach 17,790 7,908 1.4 35,977 27,259 CEM Approach - - Simple Approach for CCR mitigation (for SFTs and asset loans) - Comprehensive Approach for CCR mitigation (for SFTs and asset loans) 459,933 13,202 Total 40,461 CCR3: Standardized approach - CCR exposures by regulatory portfolio and risk weights R$ million Risk weight (FPR) 03/31/2021 Counterparties 0% 10% 20% 50% 75% 85% 100% 150% Others Total Sovereigns 135,736-1 - - - 135,737 Non-central government public sector - --49 20 - 69 entities Multilateral development banks 5,000 - - - - 5,000 Banks and other Financial Institutions 83,055-543 16,617 - 3 - 100,218 authorized by Brazil Central Bank Corporates 218,936 - - 18,903 14,895 - 252,734 Regulatory retail portfolios - - - - - Other Counterparties 1,101 - 67 - 984 - 2,152 Total 443,828-544 16,684-18,952 15,902 - 495,910 In the tables CCR1 and CCR3 there was a decrease in the exposure of repo operations mainly in central governments and central banks and in corporates. 30 Itaú Unibanco

Risk and Capital Management - Pillar 3 CCR5: Composition of collateral for CCR exposures R$ million 03/31/2021 Collateral used in derivative transactions Collateral used in SFTs and asset loans Fair value of collateral received Fair value of posted collateral Fair value of Fair value of collateral posted collateral Segregated Unsegregated Segregated Unsegregated received Cash-domestic currency-4,887 - 175,410 245,053 Cash-other currencies - 122 6,405 2,648 7,082 Domestic sovereign debt - 1,281-229,537 175,458 Government agency debt - 5,108 2 3,078 2,731 Corporate bonds - 1,425-23,943 135 Equity securities - - 1,376 16 Other collateral - 894 - 8 Total-4,887 8,830 6,407 435,992 430,483 CCR6: CCR associated with credit derivatives exposures R$ million 03/31/2021 Protection bought Protection sold Notionals Single-name credit default swaps 4,119 11,118 Index credit default swaps 28 142 Total return swaps-10,935 Total notionals 4,147 22,195 Fair values 138 (175) Positive fair value (asset) 154 102 Negative fair value (liability) (16) (277) CCR8: CCR associated with exposures to central counterparties R$ million 03/31/2021 EAD (post-CRM) RWA Exposures to qualifying CCPs (QCCPs total) 4,756 Exposures for trades at QCCPs (excluding initial margin and default fund contributions); of which 13,260 314 (i) over-the-counter (OTC) derivatives - (ii) Exchange-traded derivatives 11,856 285 (iii) Securities financing transactions 1,376 28 (iv) Netting sets where cross-product netting has been approved 28 1 Segregated initial margin-Non-segregated initial margin 12,866 4,413 Pre-funded default fund contributions 70 29 Exposures to non-QCCPs (total)-Exposures for trades at non-QCCPs (excluding initial margin and default fund contributions); of which - (i) over-the-counter (OTC) derivatives - (ii) Exchange-traded derivatives - (iii) Securities financing transactions - (iv) Netting sets where cross-product netting has been approved - Segregated initial margin-Non-segregated initial margin - Pre-funded default fund contributions - Reduction of the non-segregated guarantee portfolio to the central counterparties (QCCP). 31 Itaú Unibanco

Risk and Capital Management - Pillar 3 Securitization Exposures SECA: Qualitative disclosure requirements related to securitisation exposures Currently, Itaú Unibanco occasionally coordinates the issuance of securities in the capital market aiming the securitization of its own assets. In 2020, there were operations in which credits that were accounted for in the balance sheet were totally or partially securitized. In these cases, credits from conglomerate clients were acquired and were subsequently securitized to institutional investors with an appetite for doing so. Itaú Unibanco does not act as a sponsoring counterpart of any specific purpose company with the objective of operating in the securitization market, nor does it manage entities that acquire securities issued or originated by their own. In relation to accounting, it should be noted that (i) assets representing third-party securitizations are accounted for as well as other assets owned by the Bank, according to the brazilian accounting standards; and (ii) securitization credits originating from Itaú Unibanco's own portfolio remain accounted for in cases of credit assignment with co-obligation. In the first semester of 2020, credit assets were sold in the amount of R$ 1 billion, without substantial retained risks, to a Receivables Investment Fund. In the past 12 months, Itaú Unibanco did not assign exposures with substantial risk retention, which have been honored, repurchased or written-off as losses. SEC1: Securitisation exposures in the banking book R$ million 03/31/2021 Bank acts as originator Bank acts as sponsor Banks acts as investor Traditional Synthetic Subtotal Traditional Synthetic Subtotal Traditional Synthetic Subtotal Retail (total)-of which - - - 159-159 residential mortgage - - - --credit card - - - 152-152 other retail exposures - - - 7-7 re- securitisation - - - --Wholesale (total)-of which - - - 1,052-1,052 loans to corporates - - - 1,052-1,052 commercial mortgage - - - --lease and receivables - - - --other wholesale - - - --re- securitisation - - - --SEC2: Securitisation exposures in the trading book In Itaú Unibanco's current securitization portfolio, there are no exposures to be reported in table SEC2. SEC3: Securitisation exposures in the banking book and associated regulatory capital requirements -bank acting as originator or as sponsor In Itaú Unibanco's current securitization portfolio, there are no exposures to be reported in table SEC3. 32 Itaú Unibanco

Risk and Capital Management - Pillar 3 SEC4: Securitisation exposures in the banking book and associated capital requirements - bank acting as investor R$ million 03/31/2021 Exposure values (by RWA (by regulatory Exposure values (by risk weight bands) Capital Requirements regulatory approach) approach) 20% < FPR < 50% £ FPR < 100% £ FPR < Standardized Standardized Standardized £20% 1250% 1250% 1250% 1250% 50% 100% 1.250% approach approach approach Total exposures-1,159 - 52 1,159 52 524 650 42 52 Traditional securitisation-1,159 - 52 1,159 52 524 650 42 52 Of which securitisation-1,159 - 52 1,159 52 524 650 42 52 Of which retail underlying-157 - 2 157 2 74 23 6 2 Of which wholesale-1,002 - 50 1,002 50 450 627 36 50 Of which re- securitisation - - - - --Synthetic securitisation - - - - --Of which securitisation - - - - --Of which retail underlying - - - - --Of which wholesale - - - - --Of which re- securitisation - - - - --33 Itaú Unibanco

Risk and Capital Management - Pillar 3 Market Risk MRA: Qualitative disclosure requirements related to market risk Market risk is the possibility of losses resulting from fluctuations in the market values of positions held by a financial institution, including the risk of operations subject to variations in foreign exchange rates, interest rates, equity and commodity prices, as set forth by CMN. Price Indexes are also treated as a risk factor group. The institutional policy for market risk is in compliance with Resolution 4,557 and establishes the management structure and market risk control, which has the function of: • Provide visibility and comfort for all senior management levels that market risks assumed must be in line with Itaú Unibanco risk-return objectives; • Provide a disciplined and well informed dialogue on the overall market risk profile and its evolution over time; • Increase transparency as to how the business works to optimize results; • Provide early warning mechanisms to facilitate effective risk management, without obstructing the business objectives; and • Monitoring and avoiding the concentration of risks. Market risk is controlled by an area independent of the business units, which is responsible for the daily activities: (i) measuring and assessing risk, (ii) monitoring stress scenarios, limits and alerts, (iii) applying, analyzing and stress testing scenarios, (iv) reporting risk to the individuals responsible in the business units, in compliance with Itaú Unibanco´s governance, (v) monitoring the measures needed to adjust positions and/or risk levels to make them viable, and (vi) supporting the secure launch of new financial products. The market risk management framework categorizes transactions as part of either the Trading Book or the Baking Book, in accordance with general criteria established by CMN Resolution 4,557 and BACEN Circular 3,354. Trading Book is composed of all trades with financial and commodity instruments (including derivatives) undertaken with the intention of trading. Banking Book is predominantly characterized by portfolios originated from the banking business and operations related to balance sheet management, are intended to be either held to maturity, or sold in the medium and in the long term. The market risk management is based on the following key metrics: • Value at Risk (VaR): a statistical metric that quantifies the maximum potential economic loss expected in normal market conditions, considering a defined holding period and confidence interval; • Losses in Stress Scenarios (Stress Testing): a simulation technique to evaluate the impact, in the assets, liabilities and derivatives of the portfolio, of various risk factors in extreme market situations (based on prospective and historic scenarios); • Stop Loss: metrics that trigger a management review of positions, if the accumulated losses in a given period reach specified levels; • Concentration: cumulative exposure of certain financial instrument or risk factor calculated at market value ('MtM-Mark to Market'); and • Stressed VaR: statistical metric derived from VaR calculation, aimed at capturing the biggest risk in simulations of the current trading portfolio, taking into consideration the observable returns in historical scenarios of extreme volatility. In addition to the risk metrics described above, sensitivity and loss control measures are also analyzed. They include: • Gap Analysis: accumulated exposure of the cash flows by risk factor, which are marked-to-market and positioned by settlement dates; • Sensitivity (DV01 - Delta Variation Risk): impact on the market value of cash flows when a 1 basis point change is applied to current interest rates or on the index rates; and 34 Itaú Unibanco

Risk and Capital Management - Pillar 3 • Sensitivities to Various Risk Factors (Greeks): partial derivatives of a portfolio of options on the prices of the underlying assets, implied volatilities, interest rates and time. In an attempt to fit the transactions into the defined limits, Itaú Unibanco hedges its client transactions and proprietary positions, including investments overseas. Derivatives are the most commonly used instruments for carrying out these hedging activities, and can be characterized as either accounting or economic hedge, both of which are governed by institutional regulations at Itaú Unibanco. The structure of limits and alerts is in alignment with the board of directors' guidelines, being reviewed and approved on an annual basis. This structure extends to specific limits and is aimed at improving the process of risk monitoring and understanding as well as preventing risk concentration. Limits and alerts are calibrated based on projections of future balance sheets, stockholders' equity, liquidity, complexity and market volatility, as well as the Itaú Unibanco's risk appetite. The consumption of market risk limits is monitored and disclosed daily through exposure and sensitivity maps. The market risk area analyzes and controls the adherence of these exposures to limits and alerts and reports them timely to the Treasury desks and other structures foreseen in the governance. Itaú Unibanco uses proprietary systems to measure the consolidated market risk. The processing of these systems takes place in an access-controlled environment, being highly available, which has data safekeeping and recovery processes, and counts on an infrastructure to ensure the continuity of business in contingency (disaster recovery) situations. MR1: Market risk under standardized approach R$ million 03/31/2021 Risk factors RWAMPAD Interest Rates 29,238 Fixed rate denominated in reais (RWAJUR1 ) 6,492 Foreign exchange linked interest rate (RWAJUR2 ) 10,761 Price index linked interest rate (RWAJUR3 ) 11,985 Interest rate linked interest rate (RWAJUR4 )-Stock prices (RWAACS ) 766 Exchange rates (RWACAM ) 1,163 Commodity prices (RWACOM ) 2,288 Total 33,455 There is a certain stability in the Market Risk-Weighted Assets under the standardized approach (RWAMPAD) compared to the previous quarter, with the effect of the increase in interest exposure in the Brazilian market offset, almost entirely, by the reduction of interest exposure in external units. MRB: Qualitative disclosures on market risk in the Internal Models Approach (IMA) In the internal models approach, the stressed VaR and VaR models are used. These models are applied to operations in the Trading Book and Banking Book. For the Trading Book, the risk factors considered are: interest rates, inflation rates, exchange rates, stocks and commodities. For the Banking Book, exchange rates and commodities are considered. The VaR and stressed VaR models are used in the companies of the prudential conglomerate that are presented in the following table: 35 Itaú Unibanco

Risk and Capital Management - Pillar 3 Institution Model considered for Market Risk A1 Hedge Orange Master Fundo de Investimento Multimercado VaR and Stressed VaR Aj Títulos Públicos Fundo de Investimento Renda Fixa Referenciado DI VaR and Stressed VaR Banco Investcred Unibanco S.A. VaR and Stressed VaR Banco Itaú Argentina S.A. VaR and Stressed VaR Banco Itaú BBA S.A. VaR and Stressed VaR Banco Itaú Consignado S.A. VaR and Stressed VaR Banco Itaú Veículos S.A. VaR and Stressed VaR Banco ItauBank S.A. VaR and Stressed VaR Banco Itaucard S.A. VaR and Stressed VaR Banco Itauleasing S.A. VaR and Stressed VaR Dibens Leasing S.A.-Arrendamento Mercantil VaR and Stressed VaR Financeira Itaú CBD S.A. Crédito, Financiamento e Investimento VaR and Stressed VaR Fundo A1 Hedge Orange Fundo de Investimento em Cotas de Fundos de Investimento Multimercado VaR and Stressed VaR Fundo De Invest Dir Creditórios Não Padron NPL II VaR and Stressed VaR Fundo de Investimento em Direitos Creditórios Não-Padronizados Barzel VaR and Stressed VaR Fundo em Direitos Creditórios Cielo Emissores I VaR and Stressed VaR Fundo Fortaleza de Investimento Imobiliário VaR and Stressed VaR Fundo Kinea Ações VaR and Stressed VaR Goal Performance VaR and Stressed VaR Goal Performance II VaR and Stressed VaR Hipercard Banco Múltiplo S.A. VaR and Stressed VaR Intrag Distribuidora de Títulos e Valores Mobiliários Ltda. VaR and Stressed VaR Iresolve Companhia Securitizadora de Créditos Financeiros S.A. VaR and Stressed VaR Itaú Administradora de Consórcios Ltda. VaR and Stressed VaR Itaú Bank & Trust Bahamas Ltd. VaR and Stressed VaR Itaú Bank & Trust Cayman Ltd. VaR and Stressed VaR Itaú Bank, Ltd. VaR and Stressed VaR Itaú BBA USA Securities Inc. VaR and Stressed VaR Itaú Cia. Securitizadora de Créditos Financeiros VaR and Stressed VaR Itaú Corretora de Valores S.A. VaR and Stressed VaR Itaú Distribuidora de Títulos e Valores Mobiliários S.A. VaR and Stressed VaR Itaú Kinea Private Equity Multimercado Fundo de Investimento em Cotas de Fundos de Investimento Crédito Privado VaR and Stressed VaR Itaú Unibanco Holding S.A. VaR and Stressed VaR Itaú Unibanco Holding S.A., Grand Cayman Branch VaR and Stressed VaR Itaú Unibanco S.A. VaR and Stressed VaR Itaú Unibanco S.A., Grand Cayman Branch VaR and Stressed VaR Itaú Unibanco S.A., Nassau Branch VaR and Stressed VaR Itaú Unibanco Veículos Administradora de Consórcios Ltda. VaR and Stressed VaR Itaú Valores S.A. VaR and Stressed VaR Itauvest Distribuidora de Títulos e Val. Mobiliários S.A. VaR and Stressed VaR ITB Holding Ltd. VaR and Stressed VaR Kinea Ações Fundo de Investimento em Ações VaR and Stressed VaR Kinea Ações Fundo de Investimento em Cotas de Fundos de Investimento em Ações VaR and Stressed VaR Kinea CO-investimento Fundo de Investimento Imobiliario VaR and Stressed VaR Kinea I Private Equity FIP Multiestrategia VaR and Stressed VaR Kinea II Macro Fundo de Investimento Multimercado Crédito Privado VaR and Stressed VaR Kinea KP Fundo de Investimento Multimercado Crédito Privado VaR and Stressed VaR Kinea Oportunidade FI RF Credito Privado VaR and Stressed VaR Kinea Ventures FIP VaR and Stressed VaR Licania Fund Limited VaR and Stressed VaR Luizacred S.A. Sociedade de Crédito, Financiamento e Investimento VaR and Stressed VaR Microinvest S.A. Soc. de Crédito a Microempreendedor VaR and Stressed VaR Oiti Fundo de Investimento Multimercado Crédito Privado Investimento no Exterior VaR and Stressed VaR RedeCard S.A. VaR and Stressed VaR RT Itaú DJ Títulos Públicos Fundo de Investimento Renda Fixa Referenciado DI VaR and Stressed VaR RT Scala Renda Fixa-Fundo de Investimento em Cotas de Fundos de Investimento VaR and Stressed VaR RT Voyager Renda Fixa Crédito Privado-Fundo de Investimento VaR and Stressed VaR Tarumã Fundo Incentivado de Investimento em Debêntures de Infraestrutura Renda Fixa Crédito Privado VaR and Stressed VaR Itaú Unibanco, for regulatory purposes, uses the historical simulation methodology to calculate the VaR and Stressed VaR. This methodology uses the returns observed in the past to calculate the gains and losses of a portfolio over time, with a 99% confidence interval and a holding period of at least 10 days. On 03/31/2021, VaR represented 46% of the capital requirement, while the stressed VaR represented 54%. The same methodology is used for management purposes, that is, there are no differences between the managerial and regulatory models. In relation to the VaR model, the historical returns are daily updated. Itaú Unibanco uses in its VaR model both the unweighted approach, in which historical data have the same weight, and the weighted by the volatility of returns. For the calculation of volatilities, the Exponentially Weighted Moving Average method is used. The Historical VaR methodology with 10-day maintenance periods assumes that the expected distribution for 36 Itaú Unibanco

Risk and Capital Management - Pillar 3 possible losses and gains for the portfolio can be estimated from the historical behavior of the returns of the market risk factors to which this portfolio is exposed. The returns observed in the past are applied to current operations, generating a distribution of probability of losses and simulated gains that are used to estimate the Historical VaR, according to the 99% confidence level and using a historical period of 1,000 days. Losses and gains from linear operations are calculated by multiplying mark-to-market by returns, while non-linear operations are recalculated using historical returns. The returns used in simulating the movements of risk factors are relative. Regarding the Stressed VaR model, the calculation is performed for a time horizon of 10 working days, considering the 99% confidence level and simple returns in the historical period of one year. The historical stress period is periodically calculated for the period since 2004 and can be revised whenever deemed necessary. This can occur when the composition of Itaú Unibanco's portfolios changes significantly, when changes are observed in the results of the simulation of historical returns or when a new market crisis occurs. Losses and gains from linear operations are calculated by multiplying mark to market by returns, while nonlinear operations are recalculated using historical returns. In addition to the use of VaR, Itaú Unibanco carries out daily risk analysis in extreme scenarios through a diversified framework of stress tests, in order to capture potential significant losses in extreme market situations. The scenarios are based on historical, prospective crises and predetermined shocks in risk factors. One factor that has a great influence on the results of the tests, for example, is the correlation between the assets and the respective risk factors, and this effect is simulated in several ways in the various scenarios tested. In order to identify its greatest risks and assist in the decision-making of treasury and senior management, the results of stress tests are assessed by risk factors, as well as on a consolidated basis. The effectiveness of the VaR model is proven by backtesting techniques, by comparing hypothetical and actual daily losses and gains, with the estimated daily VaR, according to BACEN Circular 3,646. The number of exceptions to the established VaR limits must be compatible, within an acceptable statistical margin, with three different confidence intervals (99%, 97.5% and 95%), in three different historical windows (250, 500 and 750 working days). This includes nine different samples, therefore ensuring the statistical quality of the historical VaR hypothesis. Itaú Unibanco has a set of processes, which are periodically executed by the internal control teams, whose objective is to independently replicate the metrics that influence market risk capital by internal models. In addition to the results of the periodic processes, Itaú Unibanco assesses the process of measuring time horizons by risk factors and the estimate of the stress period for calculating the stressed VaR. The validation of the internal model includes several topics considered essential for the critical analysis of the model, such as, the evaluation of the model's limitations, the adequacy of the parameters used in the volatility estimate and the comprehensiveness and reliability of the input data. MR2: RWA flow statements of market risk exposures under an IMA Exposures subject to market risk The following table presents the exposures subject to market risk in the internal models approach, for calculating the capital requirement. R$ million VaR Stressed VaR Other Total RWAMINT RWAMINT-12/31/2020 4,455 5,357 12,550 22,362 Movement in risk levels 2,031 4,748-6,779 Updates/changes to the internal model - - Methodology and regulation - - Acquisitions and disposals - - Foreign exchange movements 55 (2,325)-(2,270) Other - (1,644) (1,644) RWAMINT-03/31/2021 6,541 7,780 10,906 25,227 37 Itaú Unibanco

Risk and Capital Management - Pillar 3 The increase in the RWAMINT when compared to the previous quarter was mainly due to the increase in the risk levels of the positions held by Itaú Unibanco. MR3: IMA values for trading portfolios The following table presents the VaR and stressed VaR values determined by the internal market risk models. R$ million 03/31/2021 VaR (10 days, 99%) Maximum value 241 Average value 117 Minimum value 55 Quarter end 241 Stressed VaR (10 days, 99%) Maximum value 459 Average value 207 Minimum value 101 Quarter end 221 The quarter-end VaR and stressed VaR increased when compared to the previous quarter due to an increased exposure to interest rates. MR4: Comparison of VaR estimates with gains/losses Backtesting The effectiveness of the VaR model is validated by backtesting techniques, comparing daily hypothetical and actual results with the estimated daily VaR. The daily VaR is calculated over a one-day maintenance horizon, according to the 99% confidence level and using a historical period of 1,000 days. The percentage of capital requirement associated with this model is 100%. The backtesting analysis presented below considers the ranges suggested by the Basel Committee on Banking Supervision (BCBS). The ranges are divided into: • Green (0 to 4 exceptions): backtesting results that do not suggest any problem with the quality or accuracy of the adopted models; • Yellow (5 to 9 exceptions): intermediate range group, which indicates an early warning monitoring and may indicate the need to review the model; and • Red (10 or more exceptions): need for improvement actions. The following chart shows the comparison between VaR and actual and hypothetical results. 38 Itaú Unibanco

Risk and Capital Management - Pillar 3 The Backtesting presented zero exceptions in relation to the hypothetical results and zero exceptions in relation to the actual results in the period. This number of exceptions falls within the green range. The actual results do not include fees, brokerage fees and commissions. There are no profit reserves. Total Exposure associated with Derivatives The main purpose of the derivative positions is to manage risks in the Trading Book and in the Banking Book in the corresponding risk factors. Derivatives: Trading + Banking R$ million 03/31/2021 With Central Counterparty Without Central Counterparty Onshore Offshore Onshore Offshore Risk Factors Long Short Long Short Long Short Long Short Interest Rates 117,621 (151,919) 19,797 (11,544) 50,305 (51,076) 70,890 (146,185) Foreign Exchange 196,684 (187,938) 44,145 (52,914) 27,379 (34,981) 399,228 (377,440) Equities 10,006 (11,182) 465 (855) 19 (4,720) - Commodities 1,619 (1,580)-(5)-(7) - 39 Itaú Unibanco

Risk and Capital Management - Pillar 3 IRRBBA: IRRBB risk management objectives and policies BACEN's (Central Bank of Brazil) Circular 3,876, published in January 2018, states on methodologies and procedures for evaluation of the capital adequacy, held to cover interest rates risk from instruments held in the banking book. For the purposes of this Circular, are defined: • â^†EVE (Delta Economic Value of Equity) is defined as the difference between the present value of the sum of repricing flows of instruments subject to IRRBB in a base scenario, and the present value of the sum of repricing flows of the same instruments in an interest-rate shocked scenario; • â^†NII (Delta Net Interest Income) is defined as the difference between the result of financial intermediation of instruments subject to IRRBB in a base scenario, and the result of financial intermediation of the same instruments in an interest-rate shocked scenario. The sensibility analysis introduced here are just a static evaluation of the portfolio interest rate exposure, and, therefore, don´t consider the dynamic management of the treasury desk and risk control areas, which hold the responsibility for measures to mitigate risk under an adverse situation, minimizing significant losses. Moreover, it is highlighted, though, the results presented do not translate into accountable or economic results for certain, because this analysis has, only, an interest rate risk disclosure purpose and to demonstrate the principle protection actions, considering the instruments fair value, apart from any accounting practices adopted by Itaú Unibanco. The institution uses an internal model to measure â^†EVE and â^†NII. â^†EVE results do not represent immediate impact in the stockholders' equity. Meanwhile, â^†NII results indicate potential volatility in the projected interest rates results. In compliance with the circular 3,876, the following demonstrates qualitative and quantitative details of risk management for IRRBB in Itaú Unibanco. Framework and Treatment Interest rate risk in the banking book refers to the potential risk of impact on capital sufficiency and/or on the results of financial intermediation due to adverse movements in interest rates, taking into account the principal flows of instruments held in the banking book. The main point of assets and liabilities management is to maximize the risk-return ratio of positions held in the banking book, taking into account the economic value of these assets/liabilities and the impact on actual and future bank's results. The interest rate risk managing on transactions held in the banking book occurs within the governance and hierarchy of decision-making bodies and under a limits structure and alerts approved specifically for these purpose, which is sensitive due to different levels and classes of market risk. The management structure of IRRBB has it owns risk policies and controls intended to ensure adherence to the bank's risk appetite. The IRRBB framework has granular management limits for several other risk metrics and consolidated limits for â^†EVE and â^†NII results, besides the limits associated with stress tests. The asset and liability management unit is responsible for managing timing mismatches between asset and liability flows, and minimizes interest rate risk by through strategies as economic hedge and accounting hedge. All the models associated with IRRBB have a robust independent validation process and are approved by a CTAM (Technical Model Assessment Commission). In addition, all the models and processes are assessed by internal audit. The interest rate risk framework in the banking book uses management measurements that are calculated daily for limit control. The â^†EVE and â^†NII metrics are calculated according to the risk appetite limits and the other risk metrics in terms of management risk limits. In the process of managing interest rate risk of the banking book, transactions subject to automatic options are 40 Itaú Unibanco

Risk and Capital Management - Pillar 3 calculated according to internal market models which split the products, as far as possible, into linear and nonlinear payoffs. The linear payoffs are treated similarly to any other instruments without options, and for nonlinear payoffs an additional value is computed and added on the â^†EVE and â^†NII metrics. In general terms, transactions subject to behavioral options are classified as deposits with no contractual maturity date defined or products subject to early repayment. Non-maturity deposits are classified according to their nature and stability to guarantee compliance with regulatory limits. A survival analysis model treats the products subject to pre-payment, using the historical dataset to calibrate its parameters. The instruments flows with homogeneous characteristics are adjusted by specific models to reflect, in the most appropriate way, the repricing flows of the instruments. The banking book consists of asset and liability transactions originating in different commercial channels (retail and wholesale) of Itaú Unibanco. The market risk exposures inherent in the banking book consists of various risk factors, which are primary components of the market in price formation. IRRBB also includes hedging transactions intended to minimize risks deriving from strong fluctuations of market risk factors and their accounting asymmetries. Market risk generated from structural mismatches is managed by a variety of financial instruments, such as exchange-traded and over-the-counter derivatives. In some cases, operations using derivative financial instruments can be classified as accounting hedges, depending on their risk and cash flow characteristics. In these cases, the supporting documentation is analyzed to enable the effectiveness of the hedge and other changes in the accounting process to be continuously monitored. The accounting and administrative procedures for hedging are defined in BACEN Circular 3,082. The IRRBB model includes a series of premises: • â^†EVE and â^†NII are measured on the basis of the cash flows of the banking book instruments, broken down into their risk factors to isolate the effect of the interest rate and the spread components; • For non-maturity deposits, the models are classified according to their nature and stability and distributed over time considering the regulatory limits; • The institution uses survival analysis models to handle credit transactions subject to prepayment, and empirical models for transactions subject to early redemption; • The medium-term repricing attributed to non-maturity deposits is defined as 1.24 years; • The maximum-term repricing attributed to non-maturity deposits is defined as 31.83 years. The article 39 of the circular defines the need to publish â^†EVE and â^†NII, using the standard shock scenarios described in article 11. Itaú Unibanco has opted to an additional disclosure of the metrics above, considering the internal scenarios, because of the understanding that the standard approach shocks and is application are too conservative. The institution understands that is owns internal scenarios, defined by statistical methodologies, which consider the interest rate historical distribution behavior represent in a more appropriate way the potential risk embedded in the interest rates volatility. Additionally, internal model is more adherent with the way Itaú Unibanco manages its own risks. The table below are presented the main results due the change in the interest rates over the banking book in the standardized scenarios, and, also, in the internal scenarios. It is important to note that, following the normative rules, the potential losses are represented by positive values and potential gains by negative values (between parentheses). • Parallel Up: increasing in the short-term and in the long-term interest rates; • Parallel Down: decreasing in the short-term and in the long-term interest rates; • Short-term increase: increasing in the short-term interest rates; • Short-term reduction: decreasing in the short-term interest rates; • Steepener: decreasing in the short-term interest rates and increasing the in the long-term interest rates; 41 Itaú Unibanco

Risk and Capital Management - Pillar 3 • Flattener: increasing in the short-term interest rates and decreasing the in the long-term interest rates; IRRBB1 - Quantitative information on IRRBB Potential Loss of Instruments Classified in the Banking Book arising from Interest Rate Variation Scenarios(1) (Losses are represented by positive values, while gains are represented by negative values between parentheses) R$ million 03/31/2021 12/31/2020 ÄEVE ÄNII ÄEVE ÄNII Standard (2) Internal (3) Standard (2) Internal (3) Standard (2) Internal (3) Standard (2) Internal (3) Scenarios Shocks Shocks Shocks Shocks Shocks Shocks Shocks Shocks Parallel Up 6,942 2,465 1,469 274 7,434 4,211 (1,278) (1,010) Parallel Down (7,386) (1,511) (1,391) (140) (9,304) (1,899) 1,574 986 Short rate Up 5,224 1,858 5,536 2,900 Short rate Down (5,602) (1,327) (6,138) (1,300) Steepener (1,247) (461) (1,518) (456) Flattener 3,024 903 2,874 789 Maximum 6,942 2,465 1,469 274 7,434 4,211 1,574 986 Tier I 139,552 137,157 (1) Losses in variation measurements are shown as positive values, as per Art. 13 §3º of Circular 3,876. (2) Values are calculated using internal models and standard regulatory shocks, as per Art. 39 §1º II of Circular 3,876. (3) Values are calculated using internal models and shocks, as per Art. 7º of Circular 3,876. The maximum variation of â^†EVE, with internal shocks, was R$ 2,465 millions as of March31, 2021, considering the Parallel Up Scenario shocks, a decrease of 41% when compared to December 31, 2020. For the outlier test, the maximum variation of the â^†EVE, with standardized shocks was R$ 6,942 million as of March 31, 2021, corresponding to a potential loss of 5% of Tier I, which is less than 15%-percentage that defines the institution as outlier (according to Art. 44 of Circular 3,876). The â^†NII, with internal shocks, for a horizon of a year, has maximum loss of R$ 274 million in the Parallel Up Scenario. 42 Itaú Unibanco

Risk and Capital Management - Pillar 3 Other Risks Insurance products, pension plans and premium bonds risks Products that compose portfolios of insurance companies of Itaú Unibanco are related to life and elementary insurance, as well as pension plans and premium bonds. The main risks inherent in these products are described below and their definitions are given in their respective chapters. • Underwriting Risk: possibility of losses arising from insurance products, pension plans and premium bonds that go against institution's expectations, directly or indirectly associated with technical and actuarial bases used for calculating premiums, contributions and technical provisions; • Market Risk; • Credit Risk; • Operational risk; • Liquidity risk. In line with domestic and international best practices, Itaú Unibanco has a risk management structure which ensures that risks resulting from insurance, pension and special savings products are properly assessed and reported to the relevant forums. The process of risk management for insurance, pensions and premium bond plans is independent and focus on the special nature of each risk. The aim of Itaú Unibanco is to ensure that assets serving as collateral for long-term products, with guaranteed minimum returns, are managed according to the characteristics of the liabilities, so that they are actuarially balanced and solvent over the long term. Social and Environmental Risk Itaú Unibanco understands social and environmental risk as the risk of potential losses due to exposure to social and environmental events arising from the performance of its activities, according to CMN Resolution 4,327/14. The Social and Environmental Responsibility and Sustainability Policy (PRSA) establishes the guidelines, strategies and main principles for social and environmental management, starting from institutional issues, and addressing, through specific procedures, the most relevant risks to the institution's operation. Mitigation actions on social and environmental risk are carried out through the mapping of processes, risks and controls, the monitoring of new regulations on the subject, and the listing of occurrences in internal databases. In addition to identification, the stages of prioritization, risk response, monitoring and reporting of the assessed risks complement the management of this risk at Itaú Unibanco. The management of this risk is carried out by the first line of defense, business areas that manage it in their daily activities, following the PRSA guidelines, manuals and specific procedures supplemented by the specialized assessment of the dedicated teams of Corporate Compliance, Modeling and Credit Risk and Legal and Institutional department, which work integrated in the management of all the dimensions of Social and Environmental Risk linked to the conglomerate activities. Business units also have the governance for the approval of new products and services, which includes the social and environmental risk assessment, that ensures the compliance in the new products and processes employed by the institution, as well as with specific social and environmental processes applicable to the institution's own operation (equity, branch infrastructure and technology), suppliers, credit, investments and key subsidiaries. The second line of defense, in turn, is represented by Modeling and Credit Risk, Internal Controls, as well as Compliance, through the Social and Environmental Risk Management, which supports and ensures the governance of the activities of the first line. The third line of defense, composed of Internal Audit, acts independently, carrying out the mapping and assessment of the risk's management, controls and governance. The Social and Environmental Risk Governance also includes the Social and Environmental Risk Committee, which is primarily responsible for debating and deciding on institutional and strategic issues, as well as deciding 43 Itaú Unibanco

Risk and Capital Management - Pillar 3 on products, operations, services, among others, that involve Social and Environmental Risk, including Climate Risk. Itaú Unibanco constantly seeks to evolve in the management of social and environmental risk, always attentive to the challenges demands of society. Therefore, among other actions, Itaú Unibanco has assumed and incorporated into Itaú Unibanco's internal processes a number of national and international voluntary commitments and pacts aimed at integrating social, environmental and governance aspects into Itaú Unibanco business. The main ones are the Principles for Responsible Investment (PRI), the Charter for Human Rights -Ethos, the Equator Principles (EP), the Global Pact, the Carbon Disclosure Project (CDP), the Brazilian GHG Protocol Program, the Pacto Nacional para Erradicação do Trabalho Escravo (National Pact for Eradicating Slave Labor), the Task Force on Climate-Related Financial Disclosures (TCFD), among others. Itaú Unibanco efforts to increase the knowledge of the assessment of the social and environmental criteria have been recognized as models in Brazil and abroad, as shown by the recurring presence of the institution in the major sustainability indexes abroad, such as the Dow Jones Sustainability Index, and recently, in Sustainability Index Euronext Vigeo - Emerging 70, and in Brazil, for example in the Corporate Sustainability Index, as well as the numerous prizes which Itaú Unibanco has been awarded. Model Risk The model risk arises from the incorrect development or maintenance of models, such as mistaken assumptions, and inappropriate use or application of the model. The use of models can lead to decisions that are more accurate and therefore it is a major practice in the institution. The models have supported strategic decisions in several contexts, such as credit approval, pricing, volatility curve estimation, calculation of capital, among others. Due to the increasing use of models, driven by the application of new technologies and the expansion of data use, Itaú Unibanco has improved its governance in relation to its development and monitoring, through the definition of guidelines, policies and procedures aimed at assuring the quality and mitigation of the associated risks. Regulatory or Compliance Risk Regulatory or Compliance risk is the risk associated with any nature, financial losses or damage to reputation, arising from non-compliance with external or internal standards, commitments to regulators, codes of self-regulation, methods or codes of conduct related to the activities of the Conglomerate. This risk is managed through a structured process aimed at identifying changes in the regulatory environment, analyzing their impacts on the departments of the institution and monitoring the actions directed at adherence to the regulatory requirements and codes of ethics. This structured process includes the following actions: (i) to understand the changes in the regulatory environment; (ii) to monitor regulatory trends; (iii) to care for the relationship between the institution and the regulator, self-regulatory bodies and the representation entity; (iv) to monitor action plans on regulatory or self-regulatory compliance; (v) to coordinate a program to comply with significant norms, such as Integrity and Ethics; and (vi) to report regulatory issues in Operational and Compliance Risk forums, according to the structure of committees established in internal policies. Reputational Risk Itaú Unibanco understands reputational risk as the risk arising from internal practices and/or external factors that may generate a negative perception of Itaú Unibanco by customers, employees, shareholders, investors, regulatory bodies, government, suppliers, the press and the society in general. It can impact the bank's reputation, the value of its brand and/or result in financial losses. Besides, this can affect the maintenance of existing business relationships, access to sources of fundraising, the attraction of new business and talent to compose the company's staff or even the license to operate. The institution believes that its reputation is extremely important for achieving its long-term goals, which is why it seeks the alignment of the speech, the action and the ethical and transparent practice, essential to raise the 44 Itaú Unibanco

Risk and Capital Management - Pillar 3 confidence of Itaú Unibanco's stakeholders. Itaú Unibanco's reputation depends on its strategy (vision, culture and skills) and derives from direct or indirect experience of the relationship between Itaú Unibanco and its stakeholders. Since the reputational risk directly or indirectly permeates all operations and processes of the institution, Itaú Unibanco's governance is structured in a way to ensure that potential risks are identified, analyzed and managed still in the initial phases of its operations and analysis of new products, including the use of new technologies. The treatment given to reputational risk is structured by means of many processes and internal initiatives, which, in turn, are supported by internal policies, and their main purpose is to provide mechanisms for the monitoring, management, control and mitigation of the main reputational risks. Among them are (i) risk appetite statement; (ii) process for the prevention and fight against unlawful acts; (iii) crisis management process and business continuity; (iv) processes and guidelines of the governmental and institutional relations; (v) corporate communication process; (vi) brand management process; (vii) ombudsman offices initiatives and commitment to customer satisfaction; and (viii) ethics guidelines and prevention of corruption. Financial institutions play a key role in preventing and fighting illegal acts, in particular money laundering, terrorist financing and fraud, in which the challenge is to identify and suppress increasingly sophisticated operations that seek to conceal the origin, location, disposition, ownership and movement of goods and money derived, directly or indirectly, from illegal activities. Itaú Unibanco has introduced a corporate policy in order to prevent its involvement in illegal acts and to protect its reputation and image towards employees, clients, strategic partners, suppliers, service providers, regulators and society, through a governance structure based on transparency, strict compliance with rules and regulations, including BACEN Circular 3,978/20 among others, and cooperation with police and judicial authorities. It also seeks a continuously alignment with local and international best practices for preventing and fighting against illegal acts, through investing and training eligible employees. In compliance with the guidelines of this corporate policy, Itaú Unibanco established a program to prevent and fight against illegal acts based on the following pillars: • Policies and Procedures; • Client Identification Process; • Know Your Customer (KYC) Process; • Know Your Partner (KYP) Process; • Know Your Supplier (KYS) Process; • Know Your Employee (KYE) Process; • Assessment of New Products and Services; • Compliance with Sanctions; • Monitoring, Selection and Analysis of Suspicious Operations or Situations; • Reporting Suspicious Transactions to the Regulatory Bodies; and • Training. This program applies to the entire institution, including subsidiaries and affiliates in Brazil and abroad. The preventing and combating unlawful acts governance is carried out by the Board of Directors, Audit Committee, Operational Risk Committee, Risk and Capital Management Commitee and Anti-Money Laundering Committees. The document that presents the guidelines established in the corporate program to prevent and combat unlawful acts may be seen on the www.itau.com.br/investor-relations, section Itaú Unibanco, under Corporate Governance, Rules and Policies, Policies, Corporate Policy for Prevention and Fight Against Illegal Acts. In addition, Itaú Unibanco has been developing various data analysis models to improve customer risk classification, transaction monitoring and KYC methodology to provide greater accuracy in its analysis and to decrease false-positives. Itaú Unibanco has also been innovating its modeling solutions using new methods based on machine learning techniques to identify potentially suspicious activities. Moreover, Itaú Unibanco is committed to protecting corporate information and ensuring client and general public privacy in any transactions. To this end, it has a Corporate Information Security Policy and Cyber Secutity and 45 Itaú Unibanco

Risk and Capital Management - Pillar 3 has a monitoring process and a control structure that covers technology, business areas and international units, adhering to principal regulatory bodies and external audits, and best market practices and certifications. Additionally, a Security Operation Center (SOC) that works 24/7 contributes to the cyber security of Itaú Unibanco's electronic channels and IT infrastructure, to the monitoring of operations and thus the minimization of the risk of a security incident. The Corporate Information Security and Cyber Security Policy can be viewed on the website www.itau.com.br/investor-relations, section Itaú Unibanco, under Corporate Governance, Rules and Policies, Policies, Corporate Policy on Information Security and Cyber Security. Country Risk The country risk is the risk of losses related to non-compliance with obligations in connection with borrowers, issuers, counterparties or guarantors, as a result of political-economic and social events or actions taken by the government of the country. Itaú Unibanco has a specific structure for the management and control of country risk, consisting of corporate bodies and dedicated teams, with responsibilities defined in policies. The institution has a structured and consistent procedure, including: (i) establishment of country ratings; (ii) determination of limits for countries; (iii) monitoring the use of limits. Business and Strategy Risk Business and strategy risk is the risk of a negative impact on the results or capital as a consequence of a faulty strategic planning, the making of adverse strategic decisions, the inability of Itaú Unibanco to implement the proper strategic plans and/or changes in its business environment. Itaú Unibanco has implemented many mechanisms that ensure that both the business and the strategic decision-making processes follow proper governance standards, have the active participation of executives and the Board of Directors, are based on market, macroeconomic and risk information and are aimed at optimizing the risk-return ratio. Decision-making and the definition of business and strategy guidelines, count on the full engagement of the Board of Directors, primarily through the Strategy Committee, and of the executives, through the Executive Committee. In order to handle risk adequately, Itaú Unibanco has governance and processes to involve the Risk Area in business and strategy decisions, so as to ensure that risk is managed and decisions are sustainable in the long term. They are: (i) qualifications and incentives of board members and executives; (ii) budget process; (iii) product assessment; (iv) evaluation and prospecting of proprietary mergers and acquisitions; and (v) a risk appetite framework which, for example, restricts the concentration of credit and exposure to specific and material risks. Contagion Risk Contagion Risk is the possibility of losses occurring for entities that are part of the Prudential Conglomerate as a result of financial support to unconsolidated entities, in a stressful situation, in the absence or in addition to the obligations provided for in the contract. Itaú Unibanco has a structure for risk management and control, a dedicated team and a policy that defines roles and responsibilities. This structure covers (i) the identification of entities in relation to the potential generation of contagion risk, (ii) the assessment of risks in relationships, (iii) the monitoring, control and mitigation of contagion risk, (iv) the assessment of impact on capital and liquidity and (v) reports. It is part of the scope of contagion risk governance: Related Party audiences, mainly composed of controllers, controlled and related entities (as defined in Res. 4,693/18), investments in non-consolidated entities, suppliers of critical products and services, buyers and sellers of relevant assets, third parties with products distributed by Itaú Unibanco and third parties to whom Itaú Unibanco distributes products. 46 Itaú Unibanco

Risk and Capital Management - Pillar 3 Operational Risk Operational risk is defined as the possibility of losses arising from failure, deficiency or inadequacy of internal process, people or systems or from external events that affect the achievement of strategic, tactical or operational objectives. It includes legal risk associated with inadequacy or deficiency in contracts signed by the institution, as well as penalties due to noncompliance with laws and punitive damages to third parties arising from the activities undertaken by the institution. Itaú Unibanco internally classifies its risk events in: • Internal fraud; • External fraud; • Labor claims and deficient security in the workplace; • Inadequate practices related to clients, products and services; • Damages to own physical assets or assets in use by Itaú Unibanco; • Interruption of Itaú Unibanco's activities; • Failures in information technology (IT) systems, processes or infrastructure; • Failures in the performance, compliance with deadlines and management of activities at Itaú Unibanco. Operational risk management includes conduct risk, which is subject to mitigating procedures to assess product design (suitability) and incentive models. The inspection area is responsible for fraud prevention. Irrespective of their origin, specific cases may be handled by risk committees and integrity and ethics committees. Itaú Unibanco has a governance process that is structured through forums and corporate bodies composed of senior management, which report to the Board of Directors, with well-defined roles and responsibilities in order to segregate the business and management and control activities, ensuring independence between the areas and, consequently, well-balanced decisions with respect to risks. This is reflected in the risk management process carried out on a decentralized basis under the responsibility of the business areas and by a centralized control carried out by the internal control, compliance and operational risk department, by means of methodologies, training courses, certification and monitoring of the control environment in an independent way. The managers of the executive areas use corporate methods constructed and made available by the internal control, compliance and operational risk area. Among the methodologies and tools used are the self-evaluation and the map of the institution's prioritized risks, the approval of processes, products, and system development products and projects, the monitoring of key risk indicators that and the database of operational losses, guaranteeing a single conceptual basis for managing processes, systems, projects and new products and services. Within the governance of the risk management process, regularly, the consolidated reports on risk monitoring, controls, action plans and operational losses are presented to the business area executives. In line with CMN Resolution 4,557, the document 'Public Access Report-Integrated Operational Risk Management and Internal Controls', summarized version of the institutional operational risk management policy can be found on the website www.itau.com.br/investor-relations, section Itaú Unibanco, under Corporate Governance, Rules and Policies, Reports. Crisis Management and Business Continuity Itaú Unibanco's Business Continuity Program's purpose is to protect its employees, ensure the continuity of the critical functions of its business lines and sustain both the stability of the markets in which it operates and the confidence of its customers and strategic partners in its provision of services and products. It establishes the Business Continuity Plan (BCP), which consists of modular procedures that are available for use in the event of incidents. The descriptions/characteristics of the existing plans are: • Disaster Recovery: it aims to ensure the availability and integrity of Information Technology resources and communication in the event of a failure in the primary Data Center to maintain the processing of critical systems; • Workplace Contingency: alternative facilities to perform the activities in the event the administrative buildings become unavailable; 47 Itaú Unibanco

Risk and Capital Management - Pillar 3 • Operational Contingency: alternatives to carry out critical processes whether they are systemic, procedural or emergency responses. In order to assess the efficiency of the contingency actions in the face of the interruption scenarios described in the plans and identify improvement points, tests are carried out at intervals that vary according to the plan, at least once a year. In order to keep the continuity solutions aligned with the business requirements (processes, minimum resources, legal requirements, etc) the Program applies the following tools to assess the institution: • Business Impact Analysis (BIA): evaluates the criticality and resumption requirement of the processes that support the delivery of products and services. • Threats and Vulnerabilities Analysis (AVA): identification of threats near to Itaú Unibanco's buildings. Considering the dependence that some processes have on third-party services, the Business Continuity Program conducts an assessment of the risk of unavailability of services provided with a view to resilience to threats of interruption. In addition, the institution has a Crisis Management Program, which is aimed at managing business interruption events, natural disasters, impacts of an environmental, social, and infrastructure/operational (including information technology) or of any other nature that jeopardize the image and reputation and/or viability of Itaú Unibanco's processes with its employees, clients, strategic partners and regulators, with timely and integrated responses. To assess the efficiency and identify points of improvement in contingency actions and crisis response plans, tests are carried out, whose frequency varies according to the plan (at least once a year). Independent Validation of Risk Models Itaú Unibanco validates the processes and risk models independently. This is done by a department which is separate from the business and risk control areas, to ensure that its assessments are independent. The validation method, defined in an internal policy, meets regulatory requirements such as those of BACEN Circulars 3,646 and 3,674. The validation stages include: • Verification of mathematical and theoretical development of the models; • Qualitative and quantitative analysis of the models, including the variables, construction of an independent calculator and the use of appropriate technical; • When applicable, comparison with alternative models and international benchmarks; • Historical Backtesting of the model; • The correct implementation of the models in the systems used. Additionally, the validation area assesses the stress testing program. The performance of the independent validation area and the validation of the processes and models are assessed by Internal Audit and reported to the specific senior management committees. Action plans are prepared to address opportunities identified during the independent validation process, and are monitored by the 3 lines of defense and by senior management until the conclusion. 48 Itaú Unibanco

Risk and Capital Management - Pillar 3 Glossary of Acronyms A • ASF - Available Stable Funding • AT1 - Additional Tier 1 Capital • AVA - Avaliação de Vulnerabilidade e Ameaças (Threats and Vulnerabilities Analysis) B • BACEN-Banco Central do Brasil (Central Bank of Brazil) • BCP - Business Continuity Plan • BCBS-Basel Committee on Banking Supervision • BIA - Business Impact Analysis • BIS - Bank for International Settlements C • CCF - Credit Conversion Factor • CCP - Non-Qualified Central Counterparty • CCR - Counterparty Credit Risk • CDP - Carbon Disclosure Project • CEM-Current Exposure Method • CEO-Chief Executive Officer • CET 1-Common Equity Tier I • CGRC-Comitê de Gestão de Risco e Capital (Risk and Capital Management Committee) • CMN-Conselho Monetário Nacional (National Monetary Council) • Comef-Comitê de Estabilidade Financeira (Financial Stability Committee) • CRI - Real State Receivables Certificate • CRM - Credit Risk Mitigation • CRO-Chief Risk Officer • CTAM - Comissão Técnica de Avaliação de Modelos (Technical Model Assessment Commission) • CVA-Credit Valuation Adjustment • CVM-Comissão de Valores Mobiliários (Brazilian Securities and Exchange Commission) D • DLP-Long- Term Liquidity Statement • DRL-Liquidity Risk Statement • D-SIB-Domestic Systemically Important Banks • DV-Delta Variation E • EAD - Exposure at Default • ECL - Expected Credit Losses 49 Itaú Unibanco

Risk and Capital Management - Pillar 3 • EMD - Multilateral Development Entities • EP - Equator Principles • EVE - Economic Value of Equity F • FIDC - Credit Rights Investment Funds • FCC-Credit Conversion Factor • FPR-Fator de Ponderação de Risco (weighting factor) G • GAP-Gap Analysis • GDP-Gross Domestic Product • GHG - Greenhouse Gas Protocol • Greeks - Sensitivities to Various Risk Factors • G-SIB - Global Systemically Important Banks H • HQLA - High Quality Liquid Assets I • ICAAP - Internal Capital Adequacy Assessment Process • IMA - Internal Models Approach • IPV - Independent Price Verification • IRRBB - Interest Rate Risk in the Banking Book • IT - Information Technology K • KYC - Know your Customer • KYP - Know your Partner • KYS - Know your Supplier • KYE - Know your Employee L • LCR - Liquidity Coverage Ratio M • MtM-Mark to Market N • NII - Net Interest Income • NSFR - Net Stable Funding Ratio O • OTC - Over-the-Counter P 50 Itaú Unibanco

Risk and Capital Management - Pillar 3 • PR - Patrimônio de Referência (Total Capital) • PRI - Principles for Responsible Investments • PRSA - Política de Sustentabilidade e Responsabilidade Socioambiental (The Social and Environmental Responsability and Sustainability Policy) • PCR - Potential Credit Risk • PVA - Prudent Valuation Adjustments Q • QCCP - Qualified Central Counterparties R • RA - Leverage Ratio • RAS-Risk Appetite Statement • RSF - Required Stable Funding • RWA-Risk Weighted Assets • RWACPAD-Portion relating to exposures to credit risk • RWACPrNB-amount of risk-weighted assets corresponding to credit risk exposures to the non-banking private sector, calculated for jurisdictions whose ACCPi is different from zero • RWAMINT-Portion relating to exposures to market risk, using internal approach • RWAMPAD-Portion relating to exposures to market risk, calculated using standardized approach • RWAOPAD-Portion relating to the calculation of operational risk capital requirements S • SA - Joint-Stock Company • SA-CCR - Standardized Approach to Counterparty Credit Risk • SFN - Sistema Financeiro Nacional (National Financial System) • SFT - Securities Financing Transactions • SOC - Security Operation Center T • TCFD - Task Force on Climate-Related Financial Disclosures • TLAC - Total Loss-Absorbing Capacity • TVM-Títulos de valores mobiliários (Securities) V • VaR-Value at Risk 51 Itaú Unibanco

Risk and Capital Management - Pillar 3 Glossary of Regulations • BACEN Circular No. 3,354, of June 27th, 2007 • BACEN Circular No. 3,644, of March 4th, 2013 • BACEN Circular No. 3,646, of March 04th, 2013 • BACEN Circular No. 3,674, of October 31st, 2013 • BACEN Circular No. 3,748, of February 26th, 2015 • BACEN Circular No. 3,749, of March 05th, 2015 • BACEN Circular No. 3,751 of March 19th, 2015 • BACEN Circular No. 3,769, of October 29th, 2015 • BACEN Circular No. 3,809, of August 25th, 2016 • BACEN Circular No. 3,846, of September 13rd, 2017 • BACEN Circular No. 3,869, of December 19th, 2017 • BACEN Circular Letter No. 3,706 of May 05th, 2015 • BACEN Circular Letter No. 3,907 of September 10th, 2018 • BACEN Circular Letter No. 4,068 of July 7th, 2020 • BACEN Circular Letter No. 3,876 of January 31st, 2018 • BACEN Circular Letter No. 3,082 of January 30th, 2012 • BACEN Circular Letter No. 3,978 of January 23rd, 2020 • BACEN Communication No. 36.830, of March 2nd, 2021 • BCB Resolution No. 54, of December 16th, 2020 • CMN Resolution No. 4,192, of March 1st, 2013 • CMN Resolution No. 4,193, of March 1st, 2013 • CMN Resolution No. 4,327, of April 25th, 2014 • CMN Resolution No. 4,502, of June 30th, 2016 • CMN Resolution No. 4,557, of February 23rd, 2017 • CMN Resolution No. 4,589, of June 29th, 2017 • CMN Resolution No. 4,693, of October 29th, 2018 • CMN Resolution No. 4,783, of March 6th, 2020 52 Itaú Unibanco