Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Title Change

On October 9, 2020, the Board of Directors (the "Board") of Kaleido Biosciences, Inc. (the "Company") changed Michael Bonney's role from Executive Chair of the Board to Chair of the Board, effective as of October 13, 2020, in connection with the appointment of Mr. Daniel Menichella as President and Chief Executive Officer of the Company and the dissolution of the Office of the CEO. The change in Mr. Bonney's title was not the result of any disagreement with the Company on any matters relating to the Company's operations, policies or practices.

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