Kintor Pharma
Developing Novel Drugs and Commercialization Platform
Confidential
Out-licensing
Accomplish Kintor's First Sales Revenue RMB34.23M in 2021
• Upfront payment of out-licensing contract with Fosun Pharma in India and 28 African countries
• Upfront payment of out-licensing contract with Etana in Indonesia
Global Innovation
Pioneer of Chinese Innovative Drugs' Globalization
• 3 phase III MRCTs were approved by various countries' administration (FDA included)
• 4 drug candidates(proxalutamide、 pyrilutamide、ALK-1 antibody、 GT20029)have clinical trials carried out within and out of China.
Clinical Trial
10 Clinical Trials Moved to Phase III/II Stage
• Proxalutamide 3 phase III MRCTs for COVID-19
• Pyrilutamide
1 phase III trial for male AGA in China
1 phase II trial for female AGA in China
1 phase II trial for male AGA in the U.S.
1 phase II trial for acne in China
• ALK-1 antibody 1 phase II trial for HCC in the U.S.
1 combotherapy trial with PD-1 for HCC in China
1 combotherapy trial with KN046 for various tumors in Taiwan
2 Drug Candidates Moved to Clinical Stage
• AR-PROTAC compound(GT20029)
• PD-L1/TGF-β dual-target antibody
Capacity Building
Growing Self-owned Capacity
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Achieved 1M courses/month in proxalutamide and by the end of 2022, and expects 50M courses/year.
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Suzhou factory passed QP audit of EU. Kintor set up tinctures and gels production line, and obtained drug production license.
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Zhuhai office started operating to speed up the R&D, production, and commercialization of biological drugs
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The Pinghu base covers 40,000㎡and construction will start in Q2 2022.
Capital Market
Top-up Placement and Heng Seng Composite Index Included
• Completed a top-up placement and raised HK$1.16 billion ($150M)
• The stock was included in HSCI and the HK Stock Connect
Proxalutamide
· The COVID-19 phase III MRCT for outpatient (NCT04870606) will release the final analysis top-line data soon.
· The COVID-19 phase III MRCT for outpatient (NCT04869228) will release its interim analysis data in H2 2022.
Pyrilutamide
· Phase II data of male AGA in China will be released by the leading PI at a dermotology symposium in June 2022.
· Phase II data of female AGA in China will be released in Q4 2022.
Pyrilutamide
Patient enrollment will complete for the phase III male AGA and phase II acne clinical trial in China in H1 2022.
ALK-1 Antibody
Complete FPI of the phase II clinical trial for the second-line combotherapy with Nivolumab for HCC in the U.S. in H1 2022.
GT20029
Complete all patient enrollment and dosing for phase I clinical trial in China and the U.S. in 2022.
GT90008
Complete FPI for the phase I clinical trial in China in H2 2022
NDA application and commercial production (GMP)
· COVID-19 indication
· AGA indication
· Large scale production of proxalutamide tablets in Suzhou base
*FPI: first patient in
01
Company Overview
02
Introduction of Candidates in Clinical Stage
03
Our Strategies
04
Financial Overview
Section 1
Company Overview
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Kintor Pharmaceutical Ltd. published this content on 28 March 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 29 March 2022 10:15:17 UTC.