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OFFON

KRYSTAL BIOTECH, INC.

(KRYS)
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Business Summary
Logo Krystal Biotech, Inc.
Krystal Biotech, Inc. is a clinical-stage gene therapy company. The Company is using its proprietary Skin TARgeted Delivery (STAR-D) platform to develop treatments for skin diseases. The CompanyÔÇÖs products are directed to the treatment of monogenic and congenital skin diseases, including dystrophic epidermolysis bullosa (DEB) and autosomal recessive congenital ichthyosis (ARCI). DEB is an incurable, often fatal skin blistering condition caused by mutations in the gene encoding type VII collagen (COL7), a protein that provides critical structural adhesion between skin layers in a normal individual. Beremagene geperpavec (B-VEC)a replication-defective, non-integrating HSV-1 that is based on the Company's viral gene therapy platform, is the CompanyÔÇÖs product candidate being evaluated in humans and is the subject of a planned phase III clinical trial.

Number of employees : 75 people.
Managers
Name Title Age Since
Krish S. Krishnan Chairman, President & Chief Executive Officer 55 2016
George Chen Manager-Information Technology & CSV - -
Trevor Parry, Dr. Director-IP & Scientific Affairs - -
Serene Forte, Dr. Vice President-Medical Affairs - -
Brittani Agostini Manager-Clinical Operations - -
Court Freedman, Dr. Senior Scientist - -
Suma M. Krishnan Chief Operating Officer & Director 54 2016
Dan Janney Lead Independent Director 54 2020
Dino A. Rossi Independent Director 65 2017
Kirti Wardhaman Ganorkar Independent Director 53 2017
Members of the board
Name Title Age Since
Krish S. Krishnan Chairman, President & Chief Executive Officer 55 2016
Suma M. Krishnan Chief Operating Officer & Director 54 2016
Dan Janney Lead Independent Director 54 2020
Dino A. Rossi Independent Director 65 2017
Kirti Wardhaman Ganorkar Independent Director 53 2017
Julian S. Gangolli Independent Director 62 2019
Jing Marantz Independent Director 55 2021
Christopher Mason Independent Director 62 2021
Equities
Vote QuantityFree-FloatCompany-owned sharesTotal Float
Stock A 1 22,204,627 16,743,482 75.4% 0 0.0% 75.4%
Shareholders
NameEquities%
Redmile Group LLC 2,060,132 9.28%
Krish S. Krishnan 1,886,462 8.50%
Suma M. Krishnan 1,836,064 8.27%
Lord, Abbett & Co. LLC 1,385,643 6.24%
Fidelity Management & Research Co. LLC 1,341,897 6.04%
OrbiMed Advisors LLC 994,808 4.48%
Sun Pharmaceutical Industries Limited 914,107 4.12%
Frazier Management LLC 895,000 4.03%
The Vanguard Group, Inc. 783,890 3.53%
Credit Suisse Securities (USA) LLC (Broker) 779,400 3.51%
Company contact information
Krystal Biotech, Inc.
2100 Wharton Street
Suite 701
Pittsburgh, PA 15203

Phone : +1.412.586.5830
Web : http://www.krystalbio.com