Item 8.01 Other Events

On January 14, 2021, we issued a press release providing a regulatory update on sotagliflozin in heart failure. The full text of the press release issued in connection with the announcement is attached hereto as Exhibit 99.1 and incorporated herein by this reference.

Item 9.01 Financial Statements and Exhibits



(d)  Exhibits


   Exhibit No.                                                Description
                                  Press Release of Lexicon Pharmaceuticals, Inc. dated January 14,
              99.1      -       2021
                                Cover Page Interactive Data File (embedded within the Inline XBRL
            EX-104      -       document)

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