INVESTOR PRESENTATION

NOVEMBER 2022

1

DISCLAIMERS

Important Information About Littelfuse, Inc. This presentation does not constitute or form part of, and should not be construed as, an offer or solicitation to purchase or sell securities of Littelfuse, Inc. and no investment decision should be made based upon the information provided herein. Littelfuse strongly urges you to review its filings with the Securities and Exchange Commission, which can be found at investor.littelfuse.com/sec.cfm. This website also provides additional information about Littelfuse.

"Safe Harbor" Statement Under the Private Securities Litigation Reform Act of 1995. The statements in this presentation that are not historical facts are intended to constitute "forward-lookingstatements" entitled to the safe-harborprovisions of the Private Securities Litigation Reform Act. These statements may involve risks and uncertainties, including, but not limited to, risks and uncertainties relating to general economic conditions; the severity and duration of the COVID- 19 pandemic and the measures taken in response thereto and the effects of those items on the company's business; product demand and market acceptance; the impact of competitive products and pricing; product quality problems or product recalls; capacity and supply difficulties or constraints; coal mining exposures reserves; cybersecurity matters; failure of an indemnification for environmental liability; exchange rate fluctuations; commodity and other raw material price fluctuations; the effect of Littelfuse, Inc.'s ("Littelfuse" or the "Company") accounting policies; labor disputes; restructuring costs in excess of expectations; pension plan asset returns less than assumed; integration of acquisitions; uncertainties related to political or regulatory changes; and other risks which may be detailed in the company's Securities and Exchange Commission filings. Should one or more of these risks or uncertainties materialize or should the underlying assumptions prove incorrect, actual results and outcomes may differ materially from those indicated or implied in the forward-lookingstatements. This presentation should be read in conjunction with information provided in the financial statements appearing in the company's Annual Report on Form 10-Kfor the year ended January 1, 2022. Further discussion of the risk factors of the company can be found under the caption "Risk Factors" in the company's Annual Report on Form 10-Kfor the year ended January 1, 2022, and in other filings and submissions with the SEC, each of which are available free of charge on the company's investor relations website at investor.littelfuse.com and on the SEC's website at www.sec.gov. These forward-lookingstatements are made as of the date hereof. The company does not undertake any obligation to update, amend or clarify these forward-lookingstatements to reflect events or circumstances after the date hereof or to reflect the availability of new information.

Non-GAAPFinancial Measures. The information included in this presentation includes the non-GAAP financial measures of organic net sales growth, adjusted operating margin, adjusted EBITDA margin, adjusted diluted earnings per share, adjusted effective tax rate, and free cash flow. A reconciliation of these non-GAAP financial measures to the most directly comparable GAAP financial measures are set forth in the appendix. The company believes that these non-GAAP financial measures provide useful information to investors regarding its operational performance and ability to generate cash enhancing an investor's overall understanding of its core financial performance. The company believes that these non-GAAP financial measures are commonly used by financial analysts and provide useful information to analysts. Management uses these measures when assessing the performance of the business and for business planning purposes. Note that the definitions of these non-GAAP financial measures may differ from those terms as defined or used by other companies.

Littelfuse, Inc. © 2022 2

LITTELFUSE - A COMPANY THAT GROWS

EMPOWERING A SUSTAINABLE, CONNECTED, AND SAFER WORLD

Who

What

We

We

Are

Do

How

We

Grow

  • $2.5B industrial technology company(1)
  • 19,000 innovative employees
  • Designer & manufacturer of leading technologies that improve the safety, reliability & performance of our customer's products that use electrical energy
  • Deliver solutions to 100,000+ customers through global presence in over 15 countries
  • Collaborate to provide technical & application expertise
  • Drive best-in-class shareholder returns: 21% CAGR(2)
  • Increase content & share gains in industrial, transportation & electronics applications
  • Expand presence in high-growthmarkets & geographies
  • Identify strategic acquisitions to sustain organic growth
    1. 2022 Forecast as of 11/1/22 earnings release
    2. Source: Bloomberg 12/31/12 - 12/31/21

Littelfuse, Inc. © 2022 3

2021 - 2025 GROWTH STRATEGY

EMPOWERING A SUSTAINABLE, CONNECTED, AND SAFER WORLD

Double-Digit

Best-in-Class

Top-Tier

Revenue Growth

Profitability

Shareholder Returns

Outcomes

Content &

High-Growth Markets

Strategic

Share Gains

& Geographies

Acquisitions

Our Growth Drivers

Sustainability Connectivity Safety

Structural Growth Themes

Littelfuse, Inc. © 2022 4

Q3 YTD 2022 HIGHLIGHTS VS PRIOR YEAR

Net Sales

Adj.

Adj. Diluted

Operating

Growth

GAAP EPS

EPS

Margin

+24%

$11.21

$13.53

23.0%

+13% Organic

+35%

+300 bps

Top-tier performance to date; Organic growth trajectory combined with strategy-led acquisitions continue to strengthen & diversify business

See appendix for GAAP to non-GAAP reconciliation

Littelfuse, Inc. © 2022 5

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Littelfuse Inc. published this content on 04 November 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 04 November 2022 14:01:09 UTC.