MagForce AG announced the installation completion of the new NanoTherm treatment center for patients with brain tumors at the Hufeland Clinic in M-hlhausen, Thuringia, Germany. The audit to certify electrical and medical safety has been concluded positively. Hence, the treatment of brain tumor patients is expected to commence still in December 2020. With the opening of the new NanoTherm treatment center, patients with recurrent malignant brain tumors can now be treated with MagForce's novel NanoTherm technology. NanoTherm therapy is a relatively new procedure for the focal treatment of solid tumors. Simplified summary: Magnetic nanoparticles are instilled either directly into the tumor or into the resection cavity wall. These particles are then heated by an alternating magnetic field, thereby destroying the cancer cells. The nanoparticles are tiny particles of iron oxide suspended in water, i.e. very finely distributed, with a diameter of approximately 15 nanometers. One nanometer corresponds to a millionth of a millimeter. As soon as they are applied, the particles agglomerate and remain in the tissue to be treated like an implant. The particles are then made to generate heat in an alternating magnetic field that changes polarity at up to 100,000 times per second. Depending on the therapeutic temperatures reached in the tumor or individual remaining cancer cells in the resection cavity wall and the duration of treatment, the cancer cells are either irreparably destroyed, or they become weakened and more sensitive to accompanying radio- or chemotherapy. The application method of the nanoparticles is decided individually by the treating neurosurgeon. This new technique makes it possible to fight the tumor from the inside or, after surgical removal of the tumor, to ensure that isolated residual tumor cells in the resection cavity wall - which could trigger recurrences - are fought and destroyed. The surrounding healthy tissue is spared, since the particles remain at the site of application due to their special surface structure.