MagForce AG together with its subsidiary MagForce USA, Inc. announced the successful completion of the first stage of its pivotal clinical US study for the focal ablation of intermediate risk prostate cancer. MagForce has defined the clinical procedure and standardized the NanoTherm particles instillation process. Intitial findings from the first patients have shown that with the changes to the NanoActivator and the defined instillation procedure, MagForce has observed only minimal side effects that have not only significantly improved over the studies in Germany, but are very similar to those associated with a routine biopsy. The Company will now proceed with the next stage of its study in a larger patient cohort. The purpose of this focal ablation registration study, which will enroll up to 120 men in a single arm study, is to demonstrate that NanoTherm therapy can focally ablate cancer lesions with minimal side effects for patients who have progressed to intermediate risk prostate cancer stage and are under active surveillance. By destroying these cancer lesions, it is anticipated that patients will be able to remain in Active Surveillance Programs and avoid definitive therapies such as surgery or whole gland radiation with their well-known side effects as long as possible. Building on previously conducted whole gland studies in Germany more than 10 years ago, the first stage of the study, conducted in a relatively small patient cohort with 10 patients, was designed to develop a standardized clinical focal procedure for humans with normal perfusion within the prostate. The procedure allows for accurate instillation of the NanoTherm particles with the latest, cutting-edge biopsy technology available into the targeted human prostate Region of Interest at the required concentration to destroy the cancerous cells with minimal side effects. Based on the positive findings from Stage 1, MagForce will now proceed with the next stage of the study with urological specialist centers - Texas Urology Group, University of Texas, San Antonio, and University of Washington, Seattle. To further bolster recruitment and ensure broader geographic coverage as well as allow for more patients to be treated simultaneously, MagForce has added a third study site in the Eastern region of the United States in Sarasota, Florida at the Sarasota Inverventional Radiology Center lead by Dr. Gerald Grubbs. To minimize the time needed for patient treatment, MagForce USA will streamline the focal procedure and with FDA approval, MagForce will offer the streamlined focal therapy to the patients who enroll in the next stage of MagForce's pivotal study.