Item 2.02. Results of Operations and Financial Condition.

On April 28, 2022, Medical Properties Trust, Inc. (the "Company") issued a press release announcing its financial results for the three months ended March 31, 2022. A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

Item 7.01 Regulation FD Disclosure

Beginning on April 28, 2022, the Company intends to use the presentation attached to this Current Report on Form 8-K as Exhibit 99.3 in discussions with investors. The presentation was also posted on the Company's website, www.medicalpropertiestrust.com, on April 28, 2022.

The information in this Current Report on Form 8-K, including the information set forth in Exhibit 99.1, Exhibit 99.2, and Exhibit 99.3 attached hereto, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liability of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended. In addition, this information shall not be deemed incorporated by reference in any filing of the Company with the Securities and Exchange Commission, except as expressly set forth by specific reference in any such filing.

Item 9.01. Financial Statements and Exhibits.




(d) Exhibits.

Exhibit Number         Description

99.1                     Press release dated April 28, 2022 reporting financial
                       results for the three months ended March 31, 2022

99.2                     Medical Properties Trust, Inc. 1st Quarter 2022
                       Supplemental Information

99.3                     Investor Presentation dated April 28, 2022

104                    Cover Page Interactive Data File (embedded within the Inline
                       XBRL document)



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