Vericiguat is being jointly developed with MSD.
This regulatory submission was based on positive data from the Phase III VICTORIA study published in the
'Heart failure is the number one cause of hospitalization for those over the age of 65 and affects more than 60 million people worldwide. Repetitive hospitalization, or sadly even death, is common for heart failure patients as many still experience worsening events despite being treated with existing therapies,' said Dr.
The Phase III VICTORIA data were presented at ACC.20/WCC Virtual and published in the
About Vericiguat
Vericiguat (BAY 1021189 / MK-1242) is an investigational, oral, once-daily, direct stimulator of the soluble guanylate cyclase (sGC) enzyme. Vericiguat actively restores the functioning of a critical pathway (NO-sGC-cGMP) not addressed by current therapies. While sGC is important for the function of both the blood vessels and the heart, it is insufficiently stimulated in heart failure patients resulting in myocardial and vascular dysfunction. Vericiguat is the first-in-class sGC-stimulator under development in this indication.
About Worldwide Collaboration between Bayer and MSD
Since
About Cardiology at Bayer
Bayer is an innovation leader in the area of cardiovascular diseases, with a long-standing commitment to delivering science for a better life by advancing a portfolio of innovative treatments. The heart and the kidneys are closely linked in health and disease, and Bayer is working in a wide range of therapeutic areas on new treatment approaches for cardiovascular and kidney diseases with high unmet medical needs. The cardiology franchise at Bayer already includes a number of products and several other compounds are in various stages of preclinical and clinical development. Together, these products reflect the company's approach to research, which prioritizes targets and pathways with the potential to impact the way that cardiovascular diseases are treated.
About Bayer
Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Its products and services are designed to benefit people by supporting efforts to overcome the major challenges presented by a growing and aging global population. At the same time, the Group aims to increase its earning power and create value through innovation and growth. Bayer is committed to the principles of sustainable development, and the Bayer brand stands for trust, reliability and quality throughout the world. In fiscal 2019, the Group employed around 104,000 people and had sales of
Forward-Looking Statements
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