Corporate Governance Council Principles and Recommendations

Name of entity

Mesoblast Limited

ABN/ARBN

Financial year ended:

109 431 870

30 June 2022

Our corporate governance statement1for the period above can be found at:2

These pages of our annual report:

This URL on our website:

www.mesoblast.com/company/corporate-governance

The Corporate Governance Statement is accurate and up to date as at 13 October 2022 and has been approved by the board.

The annexure includes a key to where our corporate governance disclosures can be located.3

Date:

24 October 2022

Name of authorised officer authorising lodgement:

Silviu Itescu

1"Corporategovernancestatement"isdefinedinListingRule19.12tomeanthestatementreferredtoinListingRule 4.10.3which discloses the extent to which an entity has followed the recommendations set by the ASX Corporate Governance Council during a particular reportingperiod.

Listing Rule 4.10.3 requires an entity that is included in the official list as an ASX Listing to include in its annual report either a corporate governance statement that meets the requirements of that rule or the URL of the page on its website where such a statement is located. The corporate governance statement must disclose the extent to which the entity has followed the recommendations set by the ASX Corporate Governance Council during the reporting period. If the entity has not followed a recommendation for any part of the reporting period, its corporate governance statement must separately identify that recommendation and the period during which it was not followed and state its reasons for not following the recommendation and what (if any) alternative governance practices it adopted in lieu of the recommendation during that period.

UnderListingRule4.7.4,ifanentitychoosestoincludeitscorporategovernancestatementonitswebsiteratherthaninitsannual report, it must lodge a copy of the corporate governance statement with ASX at the same time as it lodges its annual report with ASX.Thecorporategovernancestatementmustbecurrentasattheeffectivedatespecifiedinthatstatementforthepurposesof Listing Rule4.10.3.

Under Listing Rule 4.7.3, an entity must also lodge with ASX a completed Appendix 4G at the same time as it lodges its annual report with ASX. The Appendix 4G serves a dual purpose. It acts as a key designed to assist readers to locate the governance disclosures made by a listed entity under Listing Rule 4.10.3 and under the ASX Corporate Governance Council's recommendations.Italsoactsasaverificationtoolforlistedentitiestoconfirmthatthey havemetthedisclosurerequirementsof Listing Rule4.10.3.

The Appendix 4G is not a substitute for, and is not to be confused with, the entity's corporate governance statement. They serve different purposes and an entity must produce each of them separately.

2Tickwhicheveroptioniscorrectandthencompletethepagenumber(s)oftheannualreport,ortheURLofthewebpage,where your corporate governance statement can be found. You can, if you wish, delete the option which is notapplicable.

3Throughout this form, where you are given two or more options to select, you can, if you wish, delete any option which is not applicable and just retain the option that is applicable. If you select an option that includes "OR" at the end of the selection and you delete the other options, you can also, if you wish, delete the "OR" at the end of theselection.

See notes 4 and 5 below for further instructions on how to complete this form.

ME_203597255_1

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 1

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

ANNEXURE - KEY TO CORPORATE GOVERNANCE DISCLOSURES

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

PRINCIPLE 1 - LAY SOLID FOUNDATIONS FOR MANAGEMENT AND OVERSIGHT

1.1

A listed entity should have and disclose a board charter setting out:

(a) the respective roles and responsibilities of its boardand management; and

(b) those matters expressly reserved to the board andthose delegated tomanagement.

and we have disclosed a copy of our board charter at:

https://www.mesoblast.com/company/corporate-governance/role-and-composition-of-the-board

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

1.2

A listed entity should:

(a) undertake appropriate checks before appointing a directoror senior executive or putting someone forward for election as a director;and

(b)provide security holders with all material information in its possession relevant to a decision on whether or not toelect or re-elect adirector.

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

1.3

A listed entity should have a written agreement with each director and senior executive setting out the terms of their appointment.

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

1.4

The company secretary of a listed entity should be accountable directly to the board, through the chair, on all matters to do with the proper functioning of the board.

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

4 Tick the box in this column only if you have followed the relevant recommendation in full for the whole of the period above. Where the recommendation has a disclosure obligation attached, you must insert the location where that disclosure has been made, where indicated by the line with "insert location" underneath. If the disclosure in question has been made in your corporate governance statement, you need only insert "our corporate governance statement". If the disclosure has been made in your annual report, you should insert the page number(s) of your annual report (eg "pages 10-12 of our annual report"). If the disclosure has been made on your website, you should insert the URL of the web page where the disclosure has been made or can be accessed (eg "www.entityname.com.au/corporate governance/charters/").

5 If you have followed all of the Council's recommendations in full for the whole of the period above, you can, if you wish, delete this column from the form and re-format it.

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 2

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

1.5

A listed entity should:

(a)have and disclose a diversitypolicy;

(b)through its board or a committee of the board set measurable objectives for achieving gender diversity in the composition of its board, senior executives and workforce generally;and

(c)disclose in relation to each reportingperiod:

(1)the measurable objectives set for that periodto achieve gender diversity;

(2) the entity's progress towards achieving those objectives;and

(3) either:

(A)the respective proportions of men and women on the board, in senior executive positionsand across the whole workforce (including how the entity has defined "senior executive" for these purposes);or

(B)if the entity is a "relevant employer" underthe Workplace Gender Equality Act, the entity's most recent "Gender Equality Indicators", as defined in and published under thatAct.

If the entity was in the S&P / ASX 300 Index at the commencement of the reporting period, the measurable objective for achieving gender diversity in the composition of its board should be to have not less than 30% of its directors of each gender within a specified period.

and we have disclosed a copy of our diversity policy at: https://www.mesoblast.com/company/corporate-governance/key-policies

and we have disclosed the information referred to in paragraph (c) at:

…………………………………………………………………………….. [insert location]

and if we were included in the S&P / ASX 300 Index at the commencement of the reporting period our measurable objective for achieving gender diversity in the composition of its board of not less than 30% of its directors of each gender within a specified period.

☒set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

1.6

A listed entity should:

(a) have and disclose a process for periodically evaluating the performance of the board, its committees and individual directors;and

(b) disclose for each reporting period whether aperformance evaluation has been undertaken in accordance with that process during or in respect of thatperiod.

and we have disclosed the evaluation process referred to in paragraph (a) at:

https://www.mesoblast.com/company/corporate-governance/board-committees-and-charters

and whether a performance evaluation was undertaken for the reporting period in accordance with that process at:

2022 Corporate Governance Statement

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

ASX Listing Rules Appendix 4G (current at 17/7/2020)

Page 3

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

1.7

A listed entity should:

(a) have and disclose a process for evaluating theperformance of its senior executives at least once every reporting period; and

(b) disclose for each reporting period whether aperformance evaluation has been undertaken in accordance with that process during or in respect of thatperiod.

and we have disclosed the evaluation process referred to in paragraph (a) at:

A of the Form 20-F contained within Mesoblast's Annual Report 2022

and whether a performance evaluation was undertaken for the reporting period in accordance with that process at:

2022 Corporate Governance Statement

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 4

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

PRINCIPLE 2 - STRUCTURE THE BOARD TO BE EFFECTIVE AND ADD VALUE

2.1

The board of a listed entity should:

(a) have a nomination committeewhich:

(1) has at least three members, a majority of whom are independent directors;and

(2) is chaired by an independent director, anddisclose:

(3) the charter of thecommittee;

(4) the members of the committee;and

(5) as at the end of each reporting period, thenumber of times the committee met throughout the period and the individual attendances of the members at those meetings; or

(b) if it does not have a nomination committee, disclosethat fact and the processes it employs to address board succession issues and to ensure that the board has the appropriate balance of skills, knowledge, experience, independence and diversity to enable it to discharge its duties and responsibilitieseffectively.

and we have disclosed a copy of the charter of the committee at: https://www.mesoblast.com/company/corporate-governance/board-committees-and-charters

and the information referred to in paragraphs (4) and (5) at:

Item6.A of the Form 20-F contained within Mesoblast's Annual Report 2022

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

2.2

A listed entity should have and disclose a board skills matrix setting out the mix of skills that the board currently has or is looking to achieve in its membership.

and we have disclosed our board skills matrix at: 2022 Corporate Governance Statement

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

2.3

A listed entity should disclose:

(a)the names of the directors considered by the board tobe independentdirectors;

(b)if a director has an interest, position, affiliation or relationship of the type described in Box 2.3 but the board is of the opinion that it does not compromise the independence of the director, the nature of the interest, position or relationship in question and an explanation of why the board is of that opinion;and

(c)the length of service of eachdirector.

and we have disclosed the names of the directors considered by the board to be independent directors at:

2022 Corporate Governance Statement

and, where applicable, the information referred to in paragraph (b) at:

2022 Corporate GovernanceStatement

and the length of service of each director at: 2022 Corporate GovernanceStatement

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (current at 17/7/2020)

Page 5

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

2.4

A majority of the board of a listed entity should be independent directors.

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

2.5

The chair of the board of a listed entity should be an independent director and, in particular, should not be the same person as the CEO of the entity.

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

2.6

A listed entity should have a program for inducting new directors and for periodically reviewing whether there is a need for existing directors to undertake professional development to maintain the skills and knowledge needed to perform their role as directors effectively.

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

PRINCIPLE 3 - INSTIL A CULTURE OF ACTING LAWFULLY, ETHICALLY AND RESPONSIBLY

3.1

A listed entity should articulate and disclose its values.

and we have disclosed our values at:

https://www.mesoblast.com/company/corporate-governance/code-of-conduct-and-values

☐set out in our Corporate GovernanceStatement

3.2

A listed entity should:

(a)have and disclose a code of conduct for its directors, senior executives and employees;and

(b)ensure that the board or a committee of the board is informed of any material breaches of thatcode.

and we have disclosed our code of conduct at:

https://www.mesoblast.com/company/corporate-governance/code-of-conduct-and-values

☐set out in our Corporate GovernanceStatement

3.3

A listed entity should:

(a) have and disclose a whistleblower policy;and

(b) ensure that the board or a committee of the board is informed of any material incidents reported under that policy.

and we have disclosed our whistleblower policy at:

https://www.mesoblast.com/company/corporate-governance/key-policies

☐set out in our Corporate GovernanceStatement

3.4

A listed entity should:

(a)have and disclose an anti-bribery and corruption policy; and

(b)ensure that the board or committee of the boardis informed of any material breaches of thatpolicy.

and we have disclosed our anti-bribery and corruption policy at:

https://www.mesoblast.com/company/corporate-governance/key-policies

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 6

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

PRINCIPLE 4 - SAFEGUARD THE INTEGRITY OF CORPORATE REPORTS

4.1

The board of a listed entity should:

(a) have an audit committeewhich:

(1) has at least three members, all of whom arenon- executive directors and a majority of whom are independent directors;and

(2) is chaired by an independent director, who isnot the chair of theboard,

and disclose:

(3) the charter of thecommittee;

(4) the relevant qualifications and experience ofthe members of the committee;and

(5) in relation to each reporting period, the number of times the committee met throughout the periodand the individual attendances of the members atthose meetings;or

(b) if it does not have an audit committee, disclose that fact and the processes it employs that independently verify and safeguard the integrity of its corporate reporting, including the processes for the appointment andremoval of the external auditor and the rotation of the audit engagementpartner.

and we have disclosed a copy of the charter of the committee at:

https://www.mesoblast.com/company/corporate-governance/board-committees-and-charters

and the information referred to in paragraphs (4) and (5) at: Item 6.A of the Form 20-F contained within Mesoblast's Annual

Report 2022

☐set out in our Corporate GovernanceStatement

4.2

The board of a listed entity should, before it approves the entity's financial statements for a financial period, receive from its CEO and CFO a declaration that, in their opinion, the financial records of the entity have been properly maintained and that the financial statements comply with the appropriate accounting standards and give a true and fair view of the financial position and performance of the entity and that the opinion has been formed on the basis of a sound system of risk management and internal control which is operating effectively.

☐set out in our Corporate GovernanceStatement

4.3

A listed entity should disclose its process to verify the integrity of any periodic corporate report it releases to the market that is not audited or reviewed by an external auditor.

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (current at 17/7/2020)

Page 7

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

PRINCIPLE 5 - MAKE TIMELY AND BALANCED DISCLOSURE

5.1

A listed entity should have and disclose a written policy for complying with its continuous disclosure obligations under listing rule 3.1.

and we have disclosed our continuous disclosure compliance policy at:

https://www.mesoblast.com/company/corporate-governance/key-policies

☐set out in our Corporate GovernanceStatement

5.2

A listed entity should ensure that its board receives copies of all material market announcements promptly after they have been made.

☐set out in our Corporate GovernanceStatement

5.3

A listed entity that gives a new and substantive investor or analyst presentation should release a copy of the presentation materials on the ASX Market Announcements Platform ahead of the presentation.

☐set out in our Corporate GovernanceStatement

PRINCIPLE 6 - RESPECT THE RIGHTS OF SECURITY HOLDERS

6.1

A listed entity should provide information about itself and its governance to investors via its website.

and we have disclosed information about us and our governance on our website at:

https://www.mesoblast.com/company/corporate-governance

☐set out in our Corporate GovernanceStatement

6.2

A listed entity should have an investor relations program that facilitates effective two-way communication with investors.

☐set out in our Corporate GovernanceStatement

6.3

A listed entity should disclose how it facilitates and encourages participation at meetings of security holders.

and we have disclosed how we facilitate and encourage participation at meetings of security holders at:

2022 Corporate Governance Statement

☐set out in our Corporate GovernanceStatement

6.4

A listed entity should ensure that all substantive resolutions at a meeting of security holders are decided by a poll rather than by a show of hands.

☐set out in our Corporate GovernanceStatement

6.5

A listed entity should give security holders the option to receive communications from, and send communications to, the entity and its security registry electronically.

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 8

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

PRINCIPLE 7 - RECOGNISE AND MANAGE RISK

7.1

The board of a listed entity should:

(a)have a committee or committees to oversee risk, each of which:

(1) has at least three members, a majority of whom are independent directors;and

(2) is chaired by an independent director, anddisclose:

(3) the charter of thecommittee;

(4) the members of the committee;and

(5) as at the end of each reporting period, thenumber of times the committee met throughout the period and the individual attendances of the members at those meetings; or

(b) if it does not have a risk committee or committees that satisfy (a) above, disclose that fact and the processesit employs for overseeing the entity's risk management framework.

and we have disclosed a copy of the charter of the committee at:

https://www.mesoblast.com/company/corporate-governance/board-committees-and-charters

and the information referred to in paragraphs (4) and (5) at:

A of the Form 20-F contained within Mesoblast's Annual Report 2022

☐set out in our Corporate GovernanceStatement

7.2

The board or a committee of the board should:

(a) review the entity's risk management framework at least annually to satisfy itself that it continues to be soundand that the entity is operating with due regard to the risk appetite set by the board;and

(b) disclose, in relation to each reporting period,whether such a review has takenplace.

and we have disclosed whether a review of the entity's risk management framework was undertaken during the reporting period at:

2022 Corporate Governance Statement

☐set out in our Corporate GovernanceStatement

7.3

A listed entity should disclose:

(a) if it has an internal audit function, how the functionis structured and what role it performs;or

(b) ifitdoes nothaveaninternalauditfunction,thatfact and the processes it employs for evaluating and continually improving the effectiveness of its governance, risk management and internal controlprocesses.

and we have disclosed how our internal audit function is structured and what role it performs at:

2022 Corporate Governance Statement

[insert location]

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (current at 17/7/2020)

Page 9

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

7.4

A listed entity should disclose whether it has any material exposure to environmental or social risks and, if it does, how it manages or intends to manage those risks.

and we have disclosed whether we have any material exposure to environmental and social risks at:

D of the Form 20-F contained within Mesoblast's Annual Report 2022

and, if we do, how we manage or intend to manage those risks at:

D of the Form 20-F contained within Mesoblast's Annual Report 2022

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 10

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

PRINCIPLE 8 - REMUNERATE FAIRLY AND RESPONSIBLY

8.1

The board of a listed entity should:

(a) have a remuneration committeewhich:

(1) has at least three members, a majority of whom are independent directors;and

(2) is chaired by an independent director, anddisclose:

(3) the charter of thecommittee;

(4) the members of the committee;and

(5) as at the end of each reporting period, thenumber of times the committee met throughout the period and the individual attendances of the members at those meetings; or

(b) if it does not have a remuneration committee, disclose that fact and the processes it employs for setting thelevel and composition of remuneration for directors and senior executives and ensuring that such remuneration is appropriate and notexcessive.

and we have disclosed a copy of the charter of the committee at:

https://www.mesoblast.com/company/corporate-governance/board-committees-and-charters

and the information referred to in paragraphs (4) and (5) at:

A of the Form 20-F contained within Mesoblast's Annual Report 2022

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

8.2

A listed entity should separately disclose its policies and practices regarding the remuneration of non-executive directors and the remuneration of executive directors and other senior executives.

and we have disclosed separately our remuneration policies and practices regarding the remuneration of non-executive directors and the remuneration of executive directors and other senior executives at:

A of the Form 20-F contained within Mesoblast's Annual Report 2022

☐set out in our Corporate Governance StatementOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

8.3

A listed entity which has an equity-based remuneration scheme should:

(a) have a policy on whether participants are permitted to enter into transactions (whether through the use of derivatives or otherwise) which limit the economic risk of participating in the scheme;and

(b) disclose that policy or a summary ofit.

and we have disclosed our policy on this issue or a summary of it at:

https://www.mesoblast.com/company/corporate-governance/key-policies

☐set out in our Corporate Governance StatementOR

☐we do not have an equity-based remuneration schemeand this recommendation is therefore not applicableOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

ASX Listing Rules Appendix 4G (current at 17/7/2020)

Page 11

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

ADDITIONAL RECOMMENDATIONS THAT APPLY ONLY IN CERTAIN CASES

9.1

A listed entity with a director who does not speak the language in which board or security holder meetings are held or key corporate documents are written should disclose the processes it has in place to ensure the director understands and can contribute to the discussions at those meetings and understands and can discharge their obligations in relation to those documents.

and we have disclosed information about the processes in place at:

……………………………………………………………………… [insert location]

☐set out in our Corporate Governance StatementOR

☒we do not have a director in this position andthis recommendation is therefore not applicableOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

9.2

A listed entity established outside Australia should ensure that meetings of security holders are held at a reasonable place and time.

☐set out in our Corporate Governance StatementOR

☒we are established in Australia and this recommendationis therefore not applicableOR

☐we are an externally managed entity and thisrecommendation is therefore notapplicable

9.3

A listed entity established outside Australia, and an externally managed listed entity that has an AGM, should ensure that its external auditor attends its AGM and is available to answer questions from security holders relevant to the audit.

☐set out in our Corporate Governance StatementOR

☒we are established in Australia and not an externallymanaged listed entity and this recommendation is therefore not applicable

☐we are an externally managed entity that does not holdan AGM and this recommendation is therefore notapplicable

ADDITIONAL DISCLOSURES APPLICABLE TO EXTERNALLY MANAGED LISTED ENTITIES

-

Alternative to Recommendation 1.1 for externally managed listed entities:

The responsible entity of an externally managed listedentity shoulddisclose:

(a) the arrangements between the responsible entity andthe listed entity for managing the affairs of the listed entity; and

(b) the role and responsibility of the board of theresponsible entity for overseeing thosearrangements.

and we have disclosed the information referred to in paragraphs (a) and (b) at:

…………………………………………………………………………….. [insert location]

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (currentat 17/7/2020)

Page 12

Appendix 4G

Key to Disclosures Corporate Governance Council Principles and Recommendations

Corporate Governance Council recommendation

Where a box below is ticked,4we have followed the recommendation in full for the whole of the period above. We have disclosed this in our Corporate Governance Statement:

Where a box below is ticked, we have NOT followed the recommendation in full for the whole of the period above. Our reasons for not doing so are:5

-

Alternative to Recommendations 8.1, 8.2 and 8.3 for externally managed listed entities:

An externally managed listed entity should clearly disclose the terms governing the remuneration of the manager.

and we have disclosed the terms governing our remuneration as manager of the entity at:

…………………………………………………………………………….. [insert location]

☐set out in our Corporate GovernanceStatement

ASX Listing Rules Appendix 4G (current at 17/7/2020)

Page 13

CorporateGovernanceStatement

Mesoblast Limited (the Company or Mesoblast) and its Board of Directors(theBoard)arecommittedtoimplementingandachievingan effectivecorporategovernanceframeworktoensurethattheCompany ismanagedeffectivelyandinanhonestandethicalway.

A description of the Company and its controlled entities'(together,theGroup)corporategovernance practicesaresetoutbelow.Allofthesepractices, unlessotherwisestated,wereinpracticeforthefinancial year ended 30 June 2022 and comply with the ASX Corporate Governance Council's (Council) Corporate Governance Principles and Recommendations, fourth edition (theASXCGPR).

The information in this statement is current as at 13 October 2022 and has been approved by the Board.

This statement includes cross references to the Company's charters, policies and codes, relevant copies or summaries of which are available in the Corporate Governance section of the Company's website,www.mesoblast.com.Further,thisstatement should be read in conjunction with the Directors' Report,theRemunerationReport,theFinancialReport andtheEnvironmental,SocialandGovernance(ESG) Statementforthefinancialyearended30June2022, as these reports also contain information required or recommended to be included by the ASXCGPR. The Directors' Report can be found at Part 1 on the Form 20-F contained within our Annual Report (principally Item4.BandItem5.A),theRemunerationReportcan be found at Item 6 of the Form 20-F contained within the2022AnnualReport,theFinancialReportcanbe foundatItem18ofForm20-Fcontainedwithinthe2022 AnnualReport,andtheESGStatementcanbefound atItem4AoftheForm20-Fcontainedwithinthe2022 AnnualReport.

PRINCIPLE 1.

LAY SOLID FOUNDATIONS FOR MANAGEMENT AND OVERSIGHT

ROLE OF THE BOARD

The Board of Directors is primarily responsible for settingthestrategicdirectionandcorporategovernance of the Group, and for overseeing the management and operationsoftheGroup.Inparticular,theprincipalroles and responsibilities of the Board areto:

facilitateaccountabilitytotheGroupandits shareholders;

ensure timely reporting toshareholders;

providestrategicguidancetomanagement,including contributing to the development and review of the corporatestrategy;

overseemanagementoftheGroupandensurethere areeffectivemanagementprocessesinplace;

appoint,remove(ifnecessary)andmonitorthe performance of the ChiefExecutive;

reviewtheperformanceoftheBoard,individual DirectorsandthecommitteesoftheBoard;

monitor:

-

organizationalperformanceandtheachievement oftheGroup'sstrategicgoalsandobjectives;

-

financialperformanceincludingapprovalofthe annual,half-yearandquarterlyfinancialreports, and liaison with the Company'sauditors;

-

progressofmajorcapitalexpenditureandother significant corporate projects including any acquisitions ordivestments;

-

compliancewiththeGroup'scorporategovernance policies and procedures;and

-

progress in relation to the Group's diversity objectivesandcompliancewithitsdiversitypolicy;

review and approve business plans, the annual budget and financial plans (including available resourcesandmajorcapitalraisingorexpenditure initiatives);

approve major corporateinitiatives;

enhance and protect the reputation of the Group includingthroughtheGroup'sstatementofvalues and code ofconduct,

overseetheoperationoftheGroup'ssystemfor compliance and risk management;and

ensureappropriateresourcesareavailableto seniormanagement.

The Board operates in accordance with the broad principles set out in its charter, which provides a framework for the Board's effective operation.

The charter specifically addresses the following:

role,authorityandresponsibilitiesoftheBoard;

Boardcommittees;

Mesoblast Limited Corporate Governance Statement 2022 1

Board composition and election of theChair;

Directors' rights andduties;

responsibilitiesofanddelegationstomanagement;

performance of the Board;and

role of a CompanySecretary.

Asummaryofthecharterisavailableat www.mesoblast.com.

BOARD COMMITTEES

TheBoardhasdelegatedspecificauthoritytotwo committees. These committeesare:

theNominationandRemunerationCommittee;and

the Audit and RiskCommittee.

Theroleandresponsibilitiesofthesecommitteesare set out in each Board Committee Charter and summarized in Principle 2 and Principle 4 of this statement,respectively.

ROLE OF MANAGEMENT

Day to day management of the Group's operations and the implementation of the corporate strategy and policy initiatives are delegated by the Board to the Chief Executive and the executive team.

Specific limits of authority delegated to the Chief Executiveandseniorexecutiveteamareoutlinedina formaldelegationofauthoritypolicy,whichhasbeen approved by theBoard.

DIRECTOR SELECTION AND APPOINTMENT

The Company conducts appropriate checks before itappointsapersonorputsforwardtoshareholdersa newcandidateforelectionasaDirector.Theseinclude checks as to the person's character, experience, education,criminalrecord,bankruptcyhistory,probity and any other relevantmatters.

The Company also provides shareholders with all material information in its possession relevant to a decisiononwhetherornottoelectorre-electaDirector inthenoticeofmeetingprovidedtoshareholders.This includes information relevant for shareholders to be abletoassesseachDirector'sskillsandcompetencies, industry experience, time commitments, current directorships, and other relevant information in their consideration of that election, including any other interest,positionorrelationshipthatmightinfluence ontheirabilitytobearonissuesbeforetheBoardand toactinthebestinterestsoftheCompanyasawhole ratherthanintheinterestsofanindividualshareholder or otherparty.

WRITTEN AGREEMENTS WITH DIRECTORS AND SENIOR EXECUTIVES

TheCompanyhasawrittenagreementwitheach Directorandseniorexecutivesettingouttheterms of theirappointment.

Therolesandresponsibilitiesofeachnon-executive Director is set out in their letter of appointment, whichtheDirectorreceivesandcommitstoontheir appointment. The letter of appointment specifies thetimecommitment,expectationsinrelationto committee work or any other special duties attaching

totheDirector'sposition,reportinglines,remuneration arrangements, disclosure obligations inrelation to personal interests, confidentiality obligations, insurance and indemnity entitlements and details of the Company's key governance policies. A copy of the key governance policies are available at www.mesoblast.com.

Each executive Director and senior executive has enteredintoaservicecontractthatsetsoutthematerial termsofemployment,includingadescriptionofposition andduties,reportinglines,remunerationarrangements and termination rights and entitlements. Further details onarrangementswhichapplytoeachexecutiveDirector and those senior executives who are designated key managementpersonnelcanbefoundinItem6of Form 20-F contained within our Annual Report.

COMPANY SECRETARIES

The Company Secretaries are accountable directly to the Board, through the Chair, on all matters to do with the proper functioning of the Board. The Company Secretaries assist the Board in its effectiveness by monitoring that Board policies and procedures are followedandbycoordinatingthetimelycompletionand dispatch of the Board agenda and supporting papers. The Directors have direct access to the Company Secretaries who regularly communicate with them throughemail,bytelephoneandinin-personmeetings.

DIVERSITY

The Group values diversity and recognizes the benefits that diversity can bring to the organization's ability to achieve its goals. Diversity can lead to a competitive advantage through broadening the talent pool for recruitment of high quality employees, by encouraging innovation and improving a corporation's professionalismandreputation.Accordingly,theGroup is committed to promoting diversity within the Group and has adopted a formal policy outlining the Group's diversityobjectives.

Acopyofthediversitypolicyisavailableat www.mesoblast.com.

Withrespecttogenderdiversity,theGrouphasset the followingobjectives:

1)

aimtoincreasethenumberofwomenonthe Board of Directors as vacancies arise and circumstancespermit;

2)

aimtoincreasethenumberofwomenwhohold senior executive positions as vacancies arise and circumstances permit;and

3)

ensure the opportunity exists for equal gender participationinalllevelsofprofessionaldevelopment programs.

The Group is committed to developing a workplace that promotes diversity by acting in fairness and without prejudice. The Group's policy is to recruit and manage on the basis of competence and performance regardless of age, nationality, race, gender, religious beliefs,sexuality,physicalabilityorculturalbackground. Accordingly,theGrouphasnotestablishedmeasurable objectives or number targets for achieving gender diversity.

2 Mesoblast Limited Corporate Governance Statement 2022

The following table reports the Group's progress towards achieving its gender diversity objectives for points one and two above. In regard to point three, theGroupensuredthatanequalopportunityexisted for gender participation in all levels of professional developmentprogramsduringthefinancialyear.For completeness,asat30June2022,theGrouphad77 employees,ofwhich40(52%)werefemale.

Category

Number of women at 30June

2022

Number of women at 30June

2021

Increase/ (Decrease)

Board of Directors

1

1

-

Senior executive positions*

3

2

1

*Aseniorexecutivepositionisoneheldbyanexecutivewho reportsdirectlytotheChiefExecutive.Approximately33%of seniorexecutivepositionsareheldbywomen.InFY22,100% ofallvacantexecutivepositionshavebeenfilledbywomen.

The Board is conscious of the gender imbalance at board level (with only one of the six non-executive directorsbeingfemale)andhasanobjectivetoincrease this number as vacancies arise and circumstances permit.On18August2022,JaneBellwasappointed asanon-executivememberoftheBoard,pending shareholder approval at the 2022 annual general meeting.

TheBoardhasdelegatedtheresponsibilityforreviewing andreportingondiversity,specificallygenderdiversity, totheNominationandRemunerationCommittee.

BOARD PERFORMANCE EVALUATION

The performance of the Board, its committees, individual Directors and senior management is reviewed periodically. A copy of the Group's performance evaluation process is available at www.mesoblast.com. A performance evaluation wasundertakeninaccordancewiththatprocessthis financialyear.Thisreviewencompassesfeedbackon the Chair and individual non-executive Directors as wellasconsiderationofBoardsuccessionplanning, diversity, and the breadth and sufficiency of skills represented on the Board. The results of the review were discussed by the Board, for the purpose of confirmingthattheBoardcontinuestofunctionin an appropriate manner.

The Board also carries out informal performance monitoringsessionsateachquarterlymeetingofthe Board.Inaddition,Directorsareencouragedtoraise anyissuesorconcernregardingtheperformanceof theBoard,BoardcommitteesorindividualDirectors with the Chair, or if the concern relates to the Chair, withtheChairoftheAuditandRiskCommittee.

SENIOR EXECUTIVE PERFORMANCE EVALUATION

The process for assessing performance of the Chief Executiveandtheseniorexecutiveteamisdescribed intheRemunerationReport.Aperformanceevaluation forseniorexecutives,whichaccordswiththeprocess described in the Remuneration Report, was undertakenwithrespecttothefinancialyearended on 30 June2022.

PRINCIPLE 2.

STRUCTURE THE BOARD TO BE EFFECTIVE AND ADD VALUE

NOMINATION AND REMUNERATION COMMITTEE

The Board has established a Nomination and Remuneration Committee to assist it in the discharge of its responsibilities, and in particular to ensure that appointments to the Board are subject to formal, rigorousandtransparentproceduresinordertocreate anenvironmentwheretheBoardcancarryouteffective and responsible decision making and oversight. The main responsibilities of the committee areto:

conduct reviews of the membership of the Board having regard to present and future needs of the CompanyandtomakerecommendationsonBoard composition, appointments andreappointments;

conductreviewsofanddeterminetheindependence of eachDirector;

propose candidates for Boardvacancies;

overseeannualexecutiveperformanceevaluations, includingrecommendationsforlongandshortterm incentivegrantsaswellaspayreviews;

oversee Board succession, including the succession oftheChair,andreviewwhethersuccessionplansare inplacetomaintainanappropriatelybalancedmixof skills,experienceanddiversityontheBoard;

managetheprocessesinrelationtomeetingBoard diversityobjectives;

overseeseniormanagementsuccessionplans;and

assesstheeffectivenessoftheBoardinduction process.

The Nomination and Remuneration Committee operatesinaccordancewithitscharterwhichsetsout its roles and responsibilities, composition, structure and membership requirements. A summary of the Nomination and Remuneration Committee charter is available atwww.mesoblast.com.

ThefollowingindependentDirectorsarethemembers of the Nomination and Remuneration Committee as at 30 June2022:

Name

Position held during the year

William Burns

Independent chair

Joseph Swedish

Independent member

Michael Spooner

Independent member

Shawn Cline Tomasello

Independent member1

Philip Facchina

Independent member

Philip Krause

Independent member

1 Ms Shawn Cline Tomasello resigned from the Board and the Nomination and Remuneration Committee in August 2022.

Mesoblast Limited Corporate Governance Statement 2022 3

Thedetailsofthemeetingsattendedbyeachmemberof theNominationandRemunerationCommitteeduringthe 2022financialyeararesetoutinItem6.AofForm20-F contained within our AnnualReport.

BOARD SKILLS MATRIX

TheCompanyhasdevelopedaskillsmatrixsettingout the mix of skills and diversity that the Board currently has or is looking to achieve in its membership. The skillsmatrixhelpstoidentifyanygapsinthecollective skillsoftheBoardthatcanthenbeaddressedthrough professional development initiatives for Directors and inBoardsuccessionplanning.TheNominationand RemunerationCommitteeregularlyreviewsitsskillmatrix to make sure it covers the skills needed to address existing and emerging business andgovernance issues relevant to the Company.

The skills and experience that the Board has, and continuestoaddtoitsmembership,areintheareas of, but not limitedto:

Industry experience: pharmaceutical/ biotechnology productdevelopment-substantialexperienceinthe druginvestigation,testinganddevelopmentprocess;

Industry experience: pharmaceutical/biotechnology commercialization and regulatory - substantial experience in the drug commercialization process including clinical trials and path to regulatory and pricingapproval;

Industry experience: pharmaceutical/biotechnology manufacturingandsupply-substantialexperience intheglobalmanufacturing,qualitycontrolandsupply of approved pharmaceuticalproducts;

Executivemanagementandleadership:substantial experienceinmanagingandleadingorganizations at senior executive and boardlevels;

Globalbusiness/commercialexperience:substantial experienceinseniorexecutiverolesforbusinesses operating across multiple globallocations;

Strategy:substantialexperienceinthedevelopment andimplementationofstrategicdirectionandplans to deliver investor returns overtime;

Corporate financing, mergers and acquisitions: substantialexperienceincapitalraisings,mergers andacquisitionsofcompaniesandcomplementary technologies;

Financialandriskmanagement:expertiseand experience in audit, financial accounting and reporting,internalcontrols,financialdisclosure and industrytaxation;

Human resources: substantial experience in stakeholdermanagement,oversightofremuneration, incentives, equity programs, benefits, employment contracts and workplace health andsafety;

Corporate governance: substantial experience in publicentitydisclosure,managementoversightand inquiry, listing rules and compliance;and

Medical/healthcareleadership:substantialleadership experience in healthcare organizations and/or integrated healthcaredelivery.

Each of these skills is well represented on the Board.

INDEPENDENT DIRECTORS

WiththeexceptionofourChiefExecutiveandChief MedicalOfficer(whoareexecutivedirectors),asat 30June2022,theBoardwascomprisedofindependent Directors,namely:

Mr WilliamBurns;

Mr MichaelSpooner;

Mr Joseph R.Swedish;

Dr PhilipKrause;

Ms Shawn Cline Tomasello1;and

Mr Philip J.Facchina.

ADirectorisconsideredindependentifheorsheis anon-executiveDirectorandisfreeofanyinterest, position,associationorrelationshipthatmightinfluence, or reasonably be perceived to influence, in a material respect his or her capacity to bring an independent judgement to bear on issues before the Board. The BoardconsidersthefactorssetoutintheASXCGPRand outlined below when assessing the independence of eachnon-executiveDirector,beingwhethertheDirector:

is,orhasbeen,employedinanexecutivecapacityby theGroupandtherehasnotbeenaperiodofatleast three years between ceasing such employment and serving on theBoard;

receivesperformancebasedremuneration(including options or performance rights) from, or participates inanemployeeincentiveschemeof,theentity;

is,orhaswithinthelastthreeyearsbeen,apartner, director,senioremployeeorconsultantofaprovider ofmaterialprofessionalservicestotheGroup;

is,orhasbeenwithinthelastthreeyears,inamaterial business relationship (eg, as a supplier, professional advisor, consultant or customer) with the Group, or is anofficerof,orotherwiseassociatedwith,someonein such arelationship;

is,represents,orisorhasbeenwithinthelastthree years an officer or employee of, or professional adviserto,asubstantialsecurityholderoftheGroup;

hasamaterialcontractualrelationshipwiththeGroup other than as aDirector;

has close personal ties, which may be based onfamily,friendship,orothersocialorbusiness

connections,withanypersonwhofallswithinanyof the categories described above;or

hasbeenaDirectoroftheCompanyforsuchaperiod that their independence from management and substantialholdersmayhavebeencompromised.

TheBoardatleastannuallyassessestheindependence ofitsnon-executiveDirectors.Toenablethisassessment ofindependence,theCompanymaintainsaconflicts ofinterestregister,andtheDirectorsmustprovideall informationthatmayberelevanttotheassessmentat the earliestopportunity.

4 Mesoblast Limited Corporate Governance Statement 2022

Aspartofitsannualassessmentofindependence forthe2022financialyear,theBoardgavespecific considerationto:

thefactthatournon-executiveDirectorshavereceived options under our employee incentivescheme;

the independence of Mr Spooner, who performed the roleofExecutiveChairfromAugust2005toNovember 2007, at which time he resigned but remained a Director,andalsoduetoMrSpoonerhavingatenure of17yearsand9monthsasat30June2022(with 14 years and 7 months as a non-executive Director);

the independence of Mr Facchina, who is Chief Strategy Officer of SurgCenter Development. SurgCenter Development is not a security holder inMesoblast.However,someofitsprincipalswere leadinvestors in Mesoblast's successful US$110 million private placement completed in March 2021 and successful US$65 million private placement completed in August 2022.

Withrespecttotheoptionspreviouslygrantedtonon- executive Directors, it is the Board's view that these options will not interfere with the Director's capacity tobringanindependentjudgementtobearonissues beforetheBoardandtoactinthebestinterestsofthe Group as a whole. It is noted that the options granted tonon-executiveDirectors,unlikeotheroptionsgranted to employees, are not subject to any performance or service conditions orhurdles.

WithrespecttoMrSpooner'sformerroleasExecutive Chair and his continuation on the Board, the Board maintains the view that he remains an independent DirectoronthebasisthattheGrouphassignificantly expanded its operations since he held an executive role more than ten yearsago.

With respect to Mr Spooner's tenure on the Board, theBoardconsidersthatMrSpoonerisanindependent Director on the basis that he continues to bring valuableexpertise,independentjudgementandhasnot formed associations with management or others that might compromise their ability to fulfil their role as an independentDirector.

With respect to Mr Facchina, the Board considers that MrFacchinabringsindependentjudgement,experience andexpertisetotheBoardonbehalfofallshareholders and that he does not represent the interests of any particularshareholderorgroupofshareholders.

CHAIR

TheChairisresponsibleforleadingtheBoardandfor theefficientorganizationandconductoftheBoard.

The role of the Chair more specifically is to ensure Directorsareproperlybriefedinallmattersrelevant to their role and responsibilities, to facilitate Board discussionsandtomanagetheBoard'srelationship with the Chief Executive and executive team. In acceptingtheposition,theChairhasacknowledged thatitwillrequireasignificanttimecommitmentand has confirmed that other positions held will not hinderhiseffectiveperformanceintheroleofChair. TheChair,MrJosephR.Swedish,isconsideredan independentDirector.

TERM OF OFFICE

TheCompany'sconstitutionspecifiesthatnoDirector, excepttheChiefExecutive,mayholdofficeforaperiod in excess of three years, or beyond the third Annual General Meeting following the Director's election, whichever is the longer, without submitting himself or herself forre-election.

TheterminofficeheldbyeachDirectorinofficeas at 30 June 2022 is asfollows:

Director

Term as director

Position held at 30 June

2022

Joseph Swedish

4 years

Independent Chair

William Burns

8 years and

3 months

Independent vice-Chair

Silviu Itescu

18 years

Executive Director

Michael Spooner

17 years and

9 months

Independent Director

Eric Rose

9 years and

2 months

Executive Director

ShawnClineTomasello2

3 years and

11 months

Independent Director

Philip Facchina

1 year and

3 months

Independent Director

Philip Krause

3 months

Independent Director

BOARD INDUCTION AND PROFESSIONAL DEVELOPMENT

AllnewDirectorsparticipateinaninformalinduction program which covers the operation of the Board anditscommittees,andanoverviewoftheGroup's coreprograms,keystrategy,financialandrelevant operationaldocuments.Theinductionalsoincludes

meetingswithexistingDirectorsandseniorexecutivesto ensureallrelevantandmaterialinformationisexplained thoroughly. The induction provided to new Directors enables them to actively participate in Board decision- making as soon aspossible.

TheBoardencouragesDirectorstoidentifyopportunities for, and to participate in, continuing education. The Board actively assesses relevant conferences and presentations that are appropriate for them to attend, particularly in the field of regenerative medicine, to heighten their understanding of the Group's core technologies andindustry.

In addition, presentations from management and externaladvisorsareincludedintheagendaforBoard meetingsthroughouttheyeartoassistwithkeepingthe Directors updated and informed on key developments in laws and the regulatoryenvironment.

2 Ms Shawn Cline Tomasello resigned from the Board in August 2022.

Mesoblast Limited Corporate Governance Statement 2022 5

PRINCIPLE 3.

INSTIL A CULTURE OF ACTING LAWFULLY, ETHICALLY AND RESPONSIBLY

CODE OF CONDUCT AND VALUES

As part of its commitment to recognizing the legitimate interests of stakeholders, the Group has established a codeofconduct(Code),statementofvaluesandasuite of policies and procedures to guide all Directors and employeesinrespectofethicalandcompliantbehaviour expected by the Group. In summary, the Code requires that at all times all Company personnel act with the utmost integrity, objectivity and in compliance with the law and Company policies. More specifically, the Code covers thefollowing:

conflicts ofinterest;

confidentiality;

fairdealing;

protection ofassets;

compliance with laws andregulations;

reporting violations of theCode;

security trading;and

commitments tostakeholders.

AcopyoftheCodeandstatementofvaluescanbe found atwww.mesoblast.com.

OTHER POLICIES

Among its suite of policies and procedures, the CompanyhasanAnti-BriberyandAnti-CorruptionPolicy andprovidesassociatedtraininginrespectofthepolicy as well as the Code. In addition, the Company has a Disclosure of Complaints and Concerns Policy which addresses, among other things, breaches under the Company's Code, Anti-Bribery and Anti-Corruption Policy, or other Company policies. A copy of these policies can be found at www.mesoblast.com. The CompanyhasaprocessinplacetoinformtheBoardor a committee of the Board of any material breaches of the Anti-Bribery and Anti-Corruption Policy, Code and materialincidentsreportedundertheDisclosure of Complaints and Concerns Policy.

PRINCIPLE 4.

SAFEGUARDINTEGRITYOFCORPORATE REPORTS

AUDIT AND RISK COMMITTEE

TheBoardhasestablishedanAuditandRiskCommittee to which it has delegated the responsibility for ensuring thataneffectiveinternalcontrolframeworkexistswithin the Group. The main responsibilities of the Audit and RiskCommitteewithrespecttofinancialreportingareto:

review and assess the annual financial report, the half-year financial report, the Company's quarterly accountsandallotherfinancialinformationpublished bytheCompanyorreleasedtothemarket;

recommend to the Board the appointment, removal andremunerationoftheexternalauditors,andreview thetermsoftheirengagement,thescopeandquality of the audit and assessperformance;

considertheindependenceandcompetenceofthe external auditor on an ongoingbasis;

review and approve the level of non-audit services providedbytheexternalauditorsandensureitdoes notadverselyimpactonauditorindependence;

review and monitor related partytransactions;

overseetheeffectiveoperationoftherisk managementframework;

overseeandreviewtheCompany'scompliancewith the Disclosure of Complaints and Concerns policy by Mesoblastpersonnel;

assisttheBoardinreviewingtheeffectivenessofthe organization'sinternalcontrolenvironmentcovering:

-

effectivenessandefficiencyofoperationsand businessprocesses;

-

safeguarding ofassets;

-

reliabilityoffinancialreportingandmaintaining proper accounting records;and

-

compliancewithapplicablelawsandregulations; and

reporttotheBoardonmattersrelevanttothe committee's role andresponsibilities.

Infulfillingitsresponsibilities,theAuditandRisk Committee:

receivesregularreportsfrommanagementand the externalauditors;

meetswiththeexternalauditorsatleastfourtimes a year, or more frequently ifnecessary;

reviews the processes which the Chief Executive andInterimChiefFinancialOfficerhaveinplaceto support their certifications to theBoard;

reviewsanysignificantdisagreementsbetweenthe auditorsandmanagement,irrespectiveofwhether they have been resolved;and

provides the external auditors with a clear line of directcommunicationatanytimetoeithertheChair oftheAuditandRiskCommitteeortheChairofthe Board.TheAuditandRiskCommitteehasauthority, within the scope of its responsibilities, to seek any information it requires from any employee or externalparty.

The Audit and Risk Committee operates under a formal charter approved by the Board which sets out the committee's role and responsibilities, composition, structure and membership requirements and the procedures for inviting non-committee members to attend meetings. A full copy of the Audit and Risk Committee charter can be found at www.mesoblast.com.

6 Mesoblast Limited Corporate Governance Statement 2022

ThefollowingindependentDirectorsarethemembers oftheAuditandRiskCommitteeasat30June2022:

Name

Position held during the year

Michael Spooner

Independent chair

Phil Facchina

Independent member

Joseph Swedish

Independent member

AlloftheDirectorsarefinanciallyliterateandMichael Spooner has accountingqualifications.

Additionally,alltheDirectorshavevaluableandrelevant industry experience having served in the healthcare industryinseniorpositionsforanumberofyears.

Thedetailsofthemeetingsattendedbyeachmember of the Audit and Risk Committee during the 2022 financial year are set out in Item 6.A of Form 20-F contained within our AnnualReport.

CHIEF EXECUTIVE AND INTERIM CHIEF FINANCIAL OFFICER DECLARATION

The integrity of the Company's financial reporting depends upon the existence of a sound system of riskoversightandmanagementandinternalcontrol.

Management accountability for this is enhanced by the assurances it is required to give to the Board.

The Chief Executive and the Interim Chief Financial Officer provided assurance to the Board prior to releaseoftheCompany's2022financialyearfinancial statements that, in theiropinion:

thefinancialrecordsoftheCompanyforthefinancial year have been properly maintained in accordance withtheCorporationsAct2001(Cth);and

thefinancialstatementsandnotesfortherelevant

PRINCIPLE5.

MAKE TIMELY AND BALANCED DISCLOSURE

CONTINUOUS DISCLOSURE

The Company has a policy and procedures in place to ensure that it identifies and discloses any information concerning the Group that a reasonable person would expect to have a material effect on the price of the Company's securities (price sensitive information) in accordancewiththecontinuousdisclosurerequirements underASXListingRule3.1.TheCompany'spolicy in relation to market disclosure and shareholder communications can be found at www.mesoblast.com.

The Company has established an internal review committeewhichreviewsallmarketannouncements (otherthanroutineadministrativeannouncements)to ensuretheyarefactual,complywithlegalobligations, do not omit material information, provide a balanced view,andarepresentedinaclearandconciseway.

The Board receives copies of all material market announcementseitherpriortoorpromptlyafterthey have beenmade.

All price sensitive information disclosed to the ASX is posted on the Mesoblast website as soon as possible after it is disclosed to the ASX.

Where the Company holds a substantive investor or analystpresentation,includingforourquarterlyfinancial results,oronewhichcontainsmaterialnewinformation, the material used in the presentation is released concurrently to the ASX and posted on the Mesoblast website.

financialperiodcomplywiththeaccountingstandards

andgiveatrueandfairviewofthefinancialposition and performance of theGroup.

The opinions of the Chief Executive and the Interim Chief Financial Officer were formed on the basis of a soundsystemofriskmanagementandinternalcontrol which is operatingeffectively.

INTEGRITY OF PERIODIC CORPORATE REPORTS

The Company has a policy and procedures in place to ensure that periodic corporate reports which are notsubjecttoauditorreviewedbyanexternalauditor comply with relevant disclosure obligations under applicable laws. A copy of the Company's market disclosure and shareholder communications policy can be found atwww.mesoblast.com.

PRINCIPLE 6.

RESPECT THE RIGHTS OF SECURITY HOLDERS

COMPANY WEBSITE

TheCompanyprovidesinformationaboutitselfandits governanceonitswebsiteatwww.mesoblast.com.

INVESTOR RELATIONS

Mesoblast's investor relations program involves scheduled and ad hoc interactions with institutional investors, private investors and sell-side and buy-side analysts to facilitate understanding of the Group's business,corporatestrategy,governance,financialand operational performance andprospects.

Further,shareholderscancontactusatanytimethrough theGroup'sInvestorRelationsteam.Thecontact detailsareavailableonwww.mesoblast.com.TheBoard receives regular reports from our Chief Executive and InterimChiefFinancialOfficerregardingfeedbackfrom shareholders and analysts. This ensures Directors are aware of concerns being raised giving them a good understandingofcurrentmarketandshareholderviews.

Mesoblast Limited Corporate Governance Statement 2022 7

Where possible, the Company arranges for advance notification of significant group briefings (including, but not limited to, financial results announcements) and makes them widely accessible. Webcasts of analysts' calls are generally available on our website at www.mesoblast.com.

SHAREHOLDER MEETINGS

TheBoardencouragesfullparticipationbyshareholders attheAnnualGeneralMeetingtoensureahighlevelof Directoraccountabilitytoshareholdersandtoenhance shareholders' identification with the Group's strategy andgoals.Theshareholdersarerequestedtovote onmatterssuchastheadoptionoftheRemuneration Report, the granting of securities to Directors and changes to the Constitution. Importantly, Mesoblast facilitatesandencouragesshareholderparticipationat the Annual General Meeting by providing a question forumatthemeetingtoaddressindividualshareholder queries.TheCompanydeterminedallresolutionsat its2021AnnualGeneralMeetingbypoll.TheBoard is committed to monitoring ongoing developments thatmayenhancecommunicationwithshareholders, including technology developments, and the Company has held its second virtual AGM in 2021 as a result of the ongoing COVID-19 restrictions.

COMMUNICATIONS

Mesoblast gives shareholders the option to receive communications from, and send communications to, Mesoblast and its security registry electronically.

PRINCIPLE 7.

RECOGNIZE AND MANAGE RISK

AUDIT AND RISK COMMITTEE

TheBoardisresponsibleforsatisfyingitselfannually, or more frequently as required, that management hasdevelopedandimplementedasoundsystem of risk management and internal control. Detailed work on this task is delegated to the Audit and Risk CommitteeandreviewedbythefullBoard.TheAudit andRiskCommitteeisresponsibleforensuringthere areadequatepoliciesinrelationtoriskmanagement, compliance and internal control systems. They monitortheGroup'sriskmanagementbyoverseeing management'sactionsintheevaluation,management, monitoring and reporting of material operational, financial, compliance and strategic risks. In providing this oversight of the Company's risk management systems and practices, thecommittee:

reviews the framework and methodology for risk identification, the degree of risk the Company is willing to accept, the management of risk and the processesforauditingandevaluatingtheGroup'srisk managementsystem;

reviewsGroup-wideobjectivesinthecontextofthe abovementioned categories of corporaterisk;

reviewsand,wherenecessary,approvesguidelines andpoliciesgoverningtheidentification,assessment andmanagementoftheGroup'sexposuretorisk;

reviews and approves the delegations of financial authoritiesandaddressesanyneedtoupdatethese authorities on an annual basis;and

reviews compliance with agreedpolicies.

The committee recommends any actions it deems appropriate to the Board for its consideration. Details of the committee's charter, composition, structure, membership and attendance of meetings by members can be found under Principle 4 of this statement.

RISK MANAGEMENT FRAMEWORK

TheBoardisresponsibleforsatisfyingitselfannually, ormorefrequentlyasrequired,thatmanagementhas developed and implemented an effective system of risk management and internal control. Management is responsible for ensuring there are adequate policies in relation to risk management, compliance, and internal control systems. The Audit and Risk CommitteemonitorstheGroup'sriskmanagementby overseeing management's actions in the evaluation, management,monitoring,andreportingofmaterial operational,financial,compliance,strategic,andcertain Environmental,SocialandGovernance(ESG)risks.

TheGroup'sriskmanagementgroupisheadedbythe ChiefOperatingOfficer.Theriskmanagementgroupis responsible for designing, implementing, monitoring, andreportingontheGroup'smanagementofmaterial business risks and the effectiveness of the Group's riskmanagementandinternalcontrolsystem.Therisk management group reviews the Group's risks across itsbusinessandoperations,andtheGroup'smaterial businessrisksandriskmanagementframework arereviewedatleastannuallybytheAuditandRisk Committee.

In 2021, as part of the process of continual improvement, the Group developed a standardized tool to assess the Group's portfolio and corporate risk in partnership with an external risk management expert.

This is in the process of being implemented. Further detailonriskscanbefoundinthe'RiskFactors'section (Item3.D)ontheForm20-FcontainedwithinourAnnual Report.

INTERNAL AUDIT FUNCTION

In light of the size and nature of the Company's operations and activities, the Company has not established a formal separate internal audit function. The Company does have, however, a Quality Management Department with appropriate controls in place for monitoring and compliance of clinical and non-clinicalstudiesaswellasmanufacturingoperations. The Company also has a compliance function which establishes the controls for and monitors compliance with the Company's Code, policies, and applicable healthcare-related laws andregulations.

AspartofourNasdaqlisting,wearerequiredtocomply with rules 13a-14(a) and 15d-14(a) of the Securities Exchange Act of 1934, as adopted pursuant to section 302oftheSarbanes-OxleyActof2002.

8 Mesoblast Limited Corporate Governance Statement 2022

To meet these requirements, the Company's management is responsible for establishing and maintaining adequate internal control over financial reporting. External auditors and the Company's management conducted an assessment of the effectiveness of its internal control over financial reporting as of 30 June 2022 and have concluded that its internal control over financial reporting was effective as of that date.

ENVIRONMENTAL, SOCIAL, AND GOVERNANCE (ESG) RISKS

The Group monitors its exposure to risks, including ESGrisks.TheESGStatementatItem4AoftheAnnual ReportsetsoutatahighleveltheGroup'sapproach to ESG matters.

ESG issues previously identified in analysis with the assistance of an external consultant are associated directly or indirectly with risks reported in the 'Risk Factors'section(Item3.D)ontheForm20-Fcontained withinourAnnualReport.AtthisstagetheBoarddoes notconsiderthattheGrouphasanymaterialexposure toESGriskswhicharenotdisclosedthroughthe 'Risk Factors' section.

PRINCIPLE 8.

REMUNERATEFAIRLYANDRESPONSIBLY

NOMINATION AND REMUNERATION COMMITTEE

As mentioned above in Principle 2, the Board has establishedacombinedNominationandRemuneration Committee. The Nomination and Remuneration Committee advises the Board on remuneration and incentive policies and practices generally and makes specific recommendations on remuneration packages andothertermsofemploymentforexecutiveDirectors, otherseniorexecutivesandnon-executiveDirectors.

Committeemembersreceiveregularbriefingsfroman externalremunerationexpertonrecentdevelopments onremunerationandrelatedmatters.Detailsof the committee's charter, role and responsibilities, composition, structure, membership and attendance of meetings by members can be found under Principle 2 of this statement.

NON-EXECUTIVEDIRECTORREMUNERATIONPOLICY

Non-executiveDirectorremunerationconsistsofDirector fees.Inaddition,certainnon-executiveDirectors were granted options following authorization from shareholders. These options were not subject to any performanceorservicehurdlesorconditions.Further, non-executiveDirectorremunerationdoesnotinclude anyperformance-basedremunerationorbonuses.The issue of options to the non-executive Directors is not intendedtobeanannualorregularevent.

Further information on non-executive Directors' remuneration for the 2022 financial year, including principlesusedtodetermineremuneration,issetout in the RemunerationReport.

EXECUTIVEDIRECTORANDSENIOREXECUTIVES' REMUNERATIONPOLICY

Executive remuneration consists of fixed pay, performance-based remuneration and equity-based remuneration, and is closely aligned to the success of the Group. Further information on the Executive Directors and senior executives' remuneration for the 2022 financial year, including principles used to determineremuneration,issetoutintheRemuneration Report.

SHARE TRADING POLICY

The Company has developed a share trading policy which governs the trading of the Company's shares by Directors, employees and key consultants of the Company-whocollectivelyareknownas'Mesoblast Personnel'.MesoblastPersonnelarenotpermittedto trade in the Company's securities during the period starting a week prior to the last business day of the month prior to the release of our quarterly financial results,andendingonedayafterthereleaseofthose financialresults.TheBoardmayalsoimposeblackout periodsduringotherperiodsasadvisedbytheBoard from time totime.

Inaddition,nopersonisabletotradeintheCompany's shares whilst in the possession of material inside information,andnoraretheyabletoinfluenceanyother personwithregardtotradingintheCompany'sshares.

ThesharetradingpolicyprohibitsMesoblastPersonnel from trading in the Company's derivatives. This prohibition is in place to prevent such personnel from limiting their economic exposure to risk arising out of an element of remuneration which has not vested, or whichhasvestedbutremainsthesubjectofadisposal restriction.

A copy of the Company's share trading policy can be found at www.mesoblast.com.

Mesoblast Limited Corporate Governance Statement 2022 9

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Mesoblast Limited published this content on 07 November 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 07 November 2022 11:43:02 UTC.