Not for release to US wire services or distribution in the United States

March 15, 2021

Prospectus for Issue of Warrants in Connection with Previously

Announced US$110/A$138 Million Financing Led By US Strategic

Investor Group

In connection with the US$110 million private placement led by a strategic US investor group that was announced on Tuesday March 2, 2021, Mesoblast will issue warrants over 15 million shares at a price of A$2.88 per share, a 25% premium to the placement price, which may raise up to a further A$43.2 million, on or before 15 March 2028. Mesoblast has a right to call on these funds at any time during the term, subject to a share trading price of at least A$4.32 for 45 consecutive days.

A prospectus for the warrants was lodged with ASIC today and is attached.

Not an offer of securities

This announcement is not for release to US wire services or distribution in the United States. This announcement does not constitute an offer to sell, or a solicitation of an offer to buy, securities in the United States or any other jurisdiction. Any securities described in this announcement have not been registered under the US Securities Act of 1933 and may not be offered or sold in the United States except in transactions registered under the Securities Act or exempt from, or not subject to, registration under the US Securities Act and applicable US state securities laws.

Release authorized by the Chief Executive.

ME_181710703_1

Mesoblast Limited

ACN 109 431 870

ASX: MSB

Prospectus

This Prospectus relates to an offer of 15,027,327 Warrants (Offer Securities) to the Investors, which Mesoblast is required to issue to the Investors in accordance with the US$110 million capital raising announced on 2 March 2021 and the terms of the Subscription Agreements. This Prospectus has been prepared in accordance with Australian legal requirements. Please refer to the US and UK legends in Section 1.2 (if applicable). Only the Investors (or their nominee(s)) may apply for the Offer Securities.

IMPORTANT NOTICE

This document is important and should be read in its entirety. It is a prospectus issued pursuant to section 713 of the Corporations Act 2001 (Cth) (Australia). It does not, itself, contain all the information that is generally required to be set out in a full prospectus, but refers to other documents, the information of which is deemed to be incorporated into this Prospectus.

If after reading this Prospectus you have any questions about the securities being offered under this Prospectus or any other matter, then you should consult your stockbroker, accountant or other professional adviser.

This Prospectus may not be released to US wire services or distributed in the United States except by Mesoblast to Approved US Shareholders.

ME_181344432_11

Mesoblast Limited ACN 109 431 870

Prospectus

Corporate directory

2

Summary

3

1.

Important notices

5

2.

Company information

8

3.

Details of the Offer

13

4.

Purpose and use of funds raised under the Offer

16

5.

Effect on Mesoblast

17

6. Rights and liabilities attaching to any Shares issued on exercise of the Offer

Securities

21

7.

Risk factors

24

8.

Additional information

30

Glossary

39

Appendix 1 - Application Form

41

Mesoblast Limited ACN 109 431 870 - Prospectus| page 1

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Corporate directory

Directors

Registered Office

Joseph Swedish (Chairman)

Level 38

Silviu Itescu

55 Collins Street

William M Burns

Melbourne, Victoria 3000,

Donal O'Dwyer

Australia

Eric Rose

Telephone +61 3 9639 6036

Michael Spooner

Facsimile +61 3 9639 6030

Shawn Cline Tomasello

Website www.mesoblast.com

Company Secretary

Charlie Harrison and Niva Sivakumar

Share Registry

Link Market Services Limited

Tower 4, Collins Square

727 Collins Street

Docklands, Victoria 3008

Australia

Telephone + 61 1300 554 474

Facsimile + 61 2 9287 0303

Website www.linkmarketservices.com.au

Legal advisers

MinterEllison

Level 20, Collins Arch

447 Collins Street,

Melbourne, Victoria 3000

Australia

Mesoblast Limited ACN 109 431 870 -Prospectus | page 2

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Summary

Topic

Details

Where to find more

information

What is the Offer?

This Prospectus relates to the Offer to be made by

Section 3.1

Mesoblast to the Investors for the issue of the Offer

Securities, being up to 15,027,327 Warrants, which

Mesoblast is required to issue to the Investors in

accordance with the terms of their respective

Subscription Agreements.

Opening and Closing Dates

The Opening Date is 15 March 2021 and the Closing

Section 3.7

Date is 5.00pm (Melbourne time) on 17 March 2021.

Application for Offer

An application for the Offer Securities can only be made

Section 3.4

Securities

by an Investor and only by using an application form,

and in accordance with the instructions set out in the

application form. A duly completed application form

must be mailed, emailed, faxed or delivered to

Mesoblast as set out in this Prospectus.

An application must also comply with any further

requirements set out in the Subscription Agreements.

What is the purpose of the

In accordance with the terms of the Subscription

Section 3.1

Prospectus?

Agreements, Mesoblast is required to issue the Offer

Securities, which are warrants to acquire Shares in

accordance with the terms of the Subscription

Agreements, under a prospectus.

This Prospectus has been prepared in accordance with

section 713 of the Corporations Act for the purpose of

making available the Offer Securities to the Investors

under this Prospectus and enabling all Shares acquired

as a result of the Offer, including any Shares issued on

exercise of the Offer Securities, to be freely traded and

without restriction under section 707 of the Corporations

Act in accordance with the terms of the Subscription

Agreements.

Risk factors

The key risks in relation to an investment in Mesoblast

Section 7

include but are not limited to:

ξ

product risk;

ξ

manufacturing risk;

ξ

commercialisation risk;

ξ

partnering risk;

ξ

funding risk;

ξ

key personnel risk;

ξ intellectual property risk; and

ξ

regulatory risk.

Mesoblast Limited ACN 109 431 870 - Prospectus | page 3

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Disclaimer

Mesoblast Limited published this content on 15 March 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 13 April 2021 16:53:03 UTC.