Item 8.01 Other Events.

On September 15, 2021, Metacrine, Inc. (the "Company") hosted a virtual R&D day which was live webcasted and is available for viewing through the Events and Presentations page of the Investors section of the Company's website. The presentation included a written communication comprised of slides. The slides from the presentation are attached hereto as Exhibit 99.1, and are hereby incorporated by reference.

Item 9.01 Financial Statements and Exhibits.

(d) The following exhibit is furnished with this Current Report.






Exhibit
Number                                    Description
 99.1       Company Presentation Materials  .
  104     Cover Page Interactive Data File (embedded within the Inline XBRL document).


                                       1

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