Item 2.02 Results of Operations and Financial Condition.

On October 26, 2020, we filed with the Securities and Exchange Commission (the "SEC") a preliminary prospectus supplement (the "Preliminary Prospectus") pursuant to Rule 424(b) under the Securities Act of 1933, as amended, relating to its Registration Statement on Form S-3ASR (File No. 333-227209) filed with the SEC on September 6, 2018, in connection with a proposed public offering. In the Preliminary Prospectus, Mirati disclosed that it had $579.1 million in cash, cash equivalents and short-term investments as of September 30, 2020 and Mirati incurred $100.1 million in total operating expenses for the three months ended September 30, 2020. These amounts are preliminary and are subject to completion of financial closing procedures. As a result, these amounts may differ from the amounts that will be reflected in our consolidated financial statements as of and for the nine months ended September 30, 2020.

Forward-Looking Statements

This report contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this report that are not historical facts may be considered "forward-looking statements," including, but not limited to, statements regarding Mirati's preliminary unaudited cash, cash equivalents and short-term investments position as of September 30, 2020 and preliminary unaudited operating expenses for the three months ended September 30, 2020. Forward-looking statements are typically, but not always, identified by the use of words such as "may," "would," "believe," "intend," "plan," "anticipate," "estimate," "expect," and other similar terminology. Forward-looking statements are based on current expectations of management and upon what management believes to be reasonable assumptions based on information currently available to it, and are subject to risks and uncertainties. Such risks and uncertainties may cause actual results to differ materially from the expectations set forth in the forward-looking statements. Such risks and uncertainties include, but are not limited to, risks related to preliminary financial results, including the risks that the preliminary financial results reported herein reflect information available to Mirati only at this time and may differ from actual results, including in connection with Mirati's completion of financial closing procedures, as well as other risks detailed in our recent filings on Forms 10-K and 10-Q with the SEC. We undertake no obligation to update any forward-looking statements to reflect new information, events or circumstances, or to reflect the occurrence of unanticipated events.

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