Next Science Limited announced that a clinical trial has been initiated in the U.S. for XPERIENCE TM No Rinse Antimicrobial Solution. Enrollment in the 30-patient, 90-day study is currently underway. The trial, the TIFRAX (Tibial Fracture) Study, is a randomized, controlled, double-blinded, prospective study to evaluate the efficacy of XPERIENCE in helping decrease wound bioburden and surgical site infections (SSI). It will also evaluate whether XPERIENCE can improve post-operative outcomes when used as adjunct treatment to standard of care in patients undergoing tibial fracture repair. The study’s primary investigator is Dr. Robert Harris, an orthopaedic trauma surgeon with the Hughston Clinic in Columbus, Georgia. In addition to serving as the director of orthopaedic trauma for the Hughston Clinic, Dr. Harris is a fellow of the American Academy of Orthopaedic Surgeons and a member of several orthopaedic surgery associations, including the American Orthopaedic Association, the Orthopaedic Trauma Association and the Society of Military Orthopaedic Surgeons. XPERIENCE is a no-rinse solution that is designed to help prevent surgical site and post-operative infections by rinsing away debris and microorganisms. XPERIENCE breaks down biofilms, which are powerful communities of bacteria that function as a single entity with behaviors and defenses that are a leading contributor to SSIs.1 2 Biofilms account for more than 80% of microbial infections in the human body,3 according to the U.S. National Institutes of Health. In April, Next Science announced it had received 510(k) clearance from the Food and Drug Administration for the sale of XPERIENCE as a medical device in the U.S. XPERIENCE is predominantly used in orthopaedic procedures, including shoulder, hip, knee, trauma and podiatry surgeries. Future studies will look at expanding current indications.