Edison Investment Research Limited
Nicox (COX): Initiation - Focus on sight
21-Jan-2021 / 08:46 GMT/BST
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London, UK, 21 January 2021
Nicox (COX): Initiation - Focus on sight
Nicox develops drugs for eye diseases, with lead candidate NCX-470 in Phase III trials targeting the topical treatment
of glaucoma by utilising and expanding on an already-established dual IOP-lowering mechanistic approach. Top-line data
from Mont Blanc, the first of two Phase III studies, are expected in H122, and we expect a 2024 launch and sales of
over EUR450m in 2030 in the US and major markets. Nicox is well funded through the Mont Blanc inflection point and we
derive an rNPV valuation of EUR304m.
Our Nicox valuation applies a risk-adjusted net present value (nNPV) model with a 12.5% cost of capital and includes
the prospects for NCX-470, NCX-4251, and the Vyzulta and Zerviate royalties. We obtain an rNPV of EUR303.7m. After
including EUR29.4m in end-FY20 net cash, we obtain an equity valuation of EUR333.1m or EUR8.99/share. We model that Nicox's
funds on hand should last into H222 and that it will raise EUR40m between 2022 and 2024 before launching NCX-470 in 2024
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1162176 21-Jan-2021
(END) Dow Jones Newswires
January 21, 2021 03:47 ET (08:47 GMT)