The Phase III CANOPY-2 study was evaluating canakinumab in combination with the chemotherapy agent docetaxel in 237 adults with non-small cell lung cancer whose disease progressed while on or after previous platinum-based chemotherapy and PD-(L)1 inhibitor immunotherapy, the Swiss drugmaker said in a statement.
The canakinumab development program continues with two Phase III non-small cell lung cancer clinical trials ongoing in first-line and adjuvant settings, Novartis said. Findings will be presented at an upcoming medical meeting.
Canakinumab is a human monoclonal antibody that could enhance anti-tumour immune response and reduce tumour cell proliferation, survival and invasiveness, Novartis said.
(Reporting by Silke Koltrowitz; Editing by Riham Alkousaa and Louise Heavens)