Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal

Year.

On December 15, 2022, in connection with the effectiveness of new Securities and Exchange Commission rules regarding universal proxy cards, certain recent changes to the Delaware General Corporation Law (the "DGCL"), and a periodic review of the bylaws of Nurix Therapeutics, Inc. (the "Company"), the Company's board of directors (the "Board") approved and adopted the Company's amended and restated bylaws (the "Amended and Restated Bylaws"), which became immediately effective.

Among other things, the amendments effected by the Amended and Restated Bylaws:



     •    revise certain provisions relating to adjournment procedures and lists of
          stockholders entitled to vote at stockholder meetings, in each case to
          conform to recent amendments to the DGCL;



     •    update certain provisions related to the conduct of stockholder meetings,
          including clarifying that the presiding person of a stockholder meeting
          may set additional attendance or other procedures for meeting attendees
          and Rule 14a-8 proponents;



     •    revise the procedures and disclosure requirements set forth in the
          advance notice bylaw provisions, including (1) requiring additional
          information, representations and disclosures from proposing stockholders,
          proposed nominees and other persons related to a stockholder's
          solicitation of proxies, (2) restricting the number of nominees a
          stockholder may nominate for election at a meeting to the number of
          directors to be elected at such meeting, (3) requiring that proposed
          nominees be available for interviews by the Board or any Board committee
          thereof;



     •    address matters relating to Rule 14a-19 under the Securities Exchange Act
          of 1934, as amended (the "Universal Proxy Rules") (e.g., providing that
          stockholders delivering a notice of nomination certify to the Company in
          writing that they have complied with the Universal Proxy Rules
          requirements, providing the Company a remedy if a stockholder fails to
          satisfy the Universal Proxy Rules requirements, requiring that a
          stockholder providing notice pursuant to the advance notice bylaws inform
          the Company if a stockholder no longer plans to solicit proxies in
          accordance with the Universal Proxy Rules, and requiring stockholders
          intending to use the Universal Proxy Rules to provide reasonable evidence
          of the satisfaction of the requirements under the Universal Proxy Rules
          at least five business days before the meeting, etc.);



     •    require that a stockholder directly or indirectly soliciting proxies from
          other stockholders use a proxy card color other than white;



     •    require that a stockholder intending to authorize a qualified
          representative to act for such stockholder as a proxy to present a
          nomination or proposal at such meeting to give notice of such
          authorization to the Company at least three business days before the
          applicable meeting;



     •    amend the notice provisions to reflect amendments to the DGCL relating to
          electronic transmission of notices to stockholders; and



     •    add an emergency bylaw provision to provide clarity and authority to
          directors and certain officers during an emergency situation that would
          otherwise prevent a quorum of the Board or a Board committee from being
          achieved.

The Amended and Restated Bylaws also incorporate ministerial, clarifying and conforming changes, including changes to align with the language used in certain provisions of the DGCL and the Universal Proxy Rules.

The foregoing summary does not purport to be complete and is qualified in its entirety by reference to the full text of the Amended and Restated Bylaws, a copy of which is attached hereto as Exhibit 3.1 and is incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

The following exhibits are filed herewith and this list is intended to constitute the exhibit index:



3.1       Amended and Restated Bylaws of Nurix Therapeutics, Inc. (as amended and
        restated on December 15, 2022).

104     Cover Page Interactive Data File (embedded within the Inline XBRL
        document).



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