Oncodesign announced that Oncodesign has decided to strengthen its preclinical file with new studies to further develop certain data, given the potential value of the RIPK2 program for the company and the financial investments made in ODS-101, as well as the strong interest from Big Pharma and major investors in this First-in-Class approach. These new studies will focus in particular on the precise assessment of the therapeutic margin and the determination of the initial dose in humans through sophisticated modeling studies, and on the integration of a biomarker to more precisely measure the product's efficacy as early as in phase 1. As a result, the IND initially planned for mid-2021 has been postponed by a few months. Phase 1 will be organized and financed by Oncodesign in 2022, which is an essential step for a First-in-Class. This approach represents the best way to optimize the value of the RIPK2 program for potential buyers. Following the success of the LRRK2 program in partnership with Servier, which is progressing well with significant milestones (Phase 1 expected in 2022), Oncodesign is now more than ever focused on securing a partnership for the RIPK2 program, and on starting new programs associated with Nanocyclix.