ITEM 5.02.                 Departure of Directors or Certain Officers; Election of Directors;
                           Appointment of Certain Officers; Compensatory Arrangements of Certain
                           Officers.


On February 19, 2021, the Compensation Committee of the Board of Directors (the
"Committee") of OPKO Health, Inc. (the "Company") held a meeting to review
certain compensation matters for the Company's executive officers and
non-executive employees. At the meeting, the Committee: (i) granted stock
options to the Company's named executive officers to purchase the number of
shares of the Company's common stock set forth opposite their names below; (ii)
approved a cash bonus payment of $500,000 to Mr. Adam Logal, the Company's
Senior Vice President, Chief Financial Officer, Chief Accounting Officer and
Treasurer; and (iii) approved an annual salary increase for Mr. Logal from
$600,000 to $700,000. The stock options vest ratably over four years, expire on
the tenth anniversary of the grant date, and have an exercise price of $4.81 per
share, which was the fair market value per share on the date of grant.
             Name                    Title                                                          Stock Options
Phillip Frost                        Chief Executive Officer/Chairman                                         400,000
Jane H. Hsiao                        Vice Chairman/Chief Technical Officer                                    400,000
Steven D. Rubin                      Executive Vice President                                                 350,000
Adam Logal                           Senior Vice President, Chief Financial Officer, Chief                    350,000
                                     Accounting Officer and Treasurer


ITEM 9.01.        Financial Statements and Exhibits.


   (d)   Exhibits


 Exhibit No.            Description

104                     Cover Page Interactive Data File-the cover page XBRL tags are embedded
                        within the Inline XBRL document



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