Item 8.01. Other Information.

On May 17, 2022, Oragenics, Inc. ("Oragenics" or the "Company") issued a letter to its shareholders updating the shareholders on the Company's business.

A copy of the letter is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.





(d) Exhibits



Exhibit No.                               Description

   99.1         Letter dated May 17, 2022 from Oragenics to its shareholders.
    104       Cover Page Interactive Data File (embedded within the Inline XBRL
              document)

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