On October 6, 2021, Jonathan Lieber, the President and Principal Financial Officer of Organovo Holdings, Inc. (the Company"), notified the Company of his intent to resign, effective October 6, 2021, from his part-time role to pursue a full-time opportunity. Mr. Lieber's resignation is not a result of any disagreement with the Company or any matter relating to its accounting or financial policies or procedures. On October 6, 2021, the Company's Board of Directors appointed Thomas P. Hess, age 57, as the Company's newly appointed President, and Principal Financial Officer, effective October 6, 2021, in connection with the resignation of Mr. Lieber. Mr. Hess recently served as Chief Financial Officer and Senior Vice President of Finance of Genomind, Inc., until his retirement in May 2021.