Osiris Therapeutics, Inc. (NASDAQ: OSIR), a leading cellular and regenerative medicine company focused on developing and marketing products to treat conditions in wound care, orthopaedics and sports medicine, announced today that over 52 million commercial beneficiaries are covered for Grafix®.

“I am pleased to provide the current status of beneficiary access to Grafix,” said Cynthia Sherman, US Head, Market Access and Reimbursement. “To date, we have secured over 52 million covered lives in the commercial sector. Within the past month alone, we have obtained coverage in four large regional plans. Additionally, we have 100% Medicare coverage for Grafix in all settings of care while Grafix is covered for over 36 million Medicaid lives and continues to grow.”

“Osiris continues to make positive strides in market access,” said Dwayne Montgomery, President and CEO. “Securing further reimbursement is a top priority and the strong body of clinical evidence for Grafix serves as a catalyst for attaining coverage. With each additional national and regional plan, more patients will have access to use our proprietary advanced cryopreserved technology.”

About Osiris Therapeutics

Osiris Therapeutics, Inc., based in Columbia, Maryland, is a leader in researching, developing and marketing cellular regenerative medicine products that improve the health and lives of patients and lower overall healthcare costs. Having developed the world’s first approved stem cell drug, Osiris works to further advance the medical field. Osiris’ research and development in biotechnology focuses on innovation in regenerative medicine – including bioengineering, stem cell research and viable tissue based products. Osiris has achieved commercial success with products in orthopaedics, sports medicine and wound care, including BIO4®, a viable bone matrix, Cartiform®, a viable osteochondral allograft, Grafix, a cryopreserved placental membrane, TruSkin™, a viable human skin allograft and Stravix™, a durable placental allograft.

Osiris, Grafix and Cartiform are registered trademarks of Osiris Therapeutics, Inc.; TruSkin and Stravix are trademarks of Osiris Therapeutics, Inc. BIO4 is a registered trademark of Stryker Corporation (NYSE: SYK). More information can be found on the company's website, www.Osiris.com. (OSIR-G)

Forward-Looking Statements

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