PRESS RELEASE : PAION AG ANNOUNCES FULLY UNDERWRITTEN RIGHTS ISSUE OF ALMOST EUR 8 MILLION AND PUBLISHES PRELIMINARY, UNAUDITED KEY GROUP FINANCIALS FOR 2020

DGAP-News: PAION AG / Key word(s): Preliminary Results/Capital Increase 
PAION AG ANNOUNCES FULLY UNDERWRITTEN RIGHTS ISSUE OF ALMOST EUR 8 MILLION AND PUBLISHES PRELIMINARY, UNAUDITED KEY 
GROUP FINANCIALS FOR 2020 
2021-03-19 / 20:16 
The issuer is solely responsible for the content of this announcement. 
=---------------------------------------------------------------------------------------------------------------------- 
NOT FOR DISTRIBUTION OR RELEASE, DIRECTLY OR INDIRECTLY, IN OR INTO THE UNITED STATES OR ANY OTHER JURISDICTION IN 
WHICH THE DISTRIBUTION OR RELEASE WOULD BE UNLAWFUL. 
PAION AG ANNOUNCES FULLY UNDERWRITTEN RIGHTS ISSUE OF ALMOST EUR 8 MILLION AND PUBLISHES PRELIMINARY, UNAUDITED KEY 
GROUP FINANCIALS FOR 2020 
- Fully underwritten almost EUR 8 million capital increase with subscription rights 
- Group financial figures 2020 in line with forecast, increase in revenues and positive net result for the year 2020 
- Successful launches in Japan, China and the U.S. 
Aachen (Germany), 19 March 2021 - The Management Board of the specialty pharmaceutical company PAION AG (PA8; ISIN 
DE000A0B65S3; Frankfurt Stock Exchange, Prime Standard) ("PAION" or the "Company") today decided with the approval of 
the Supervisory Board of the same day, to increase the Company's registered share capital against contribution in cash 
from EUR 66,241,493.00 by EUR 5,095,499.00 to EUR 71,336,992.00 by issuing 5,095,499 new, registered, no-par value 
shares with a notional value of EUR 1.00 each (the "New Shares"). The subscription price is EUR 1.54 per share. 
PAION will receive gross proceeds of almost EUR 8 million from the capital increase with subscription rights. Moreover, 
PAION will draw down the third tranche of the financing agreement with the European Investment Bank (EIB) in the amount 
of EUR 7.5 million. 
PAION will use the net proceeds from the capital increase to prepare commercial launches for its product portfolio in 
selected European countries and for general corporate purposes. 
Commercial partner activities 
In Japan, licensee Mundipharma successfully launched Anerem^(R) (remimazolam) in mid-2020 with first commercial product 
sales. By the end of 2020, Mundipharma reported they had about 400 hospitals opening account for Anerem^(R). According 
to Mundipharma, this exceeded their original target by close to 100%. In addition, they are supporting several 
Investigator Initiated Trials. 
In China, licensee Yichang Humanwell also successfully launched remimazolam in the third quarter of 2020. By the end of 
2020, Yichang Humanwell reported having launched Ruima^(R) (remimazolam) to hospitals in 31 Chinese provinces. 
Remimazolam sales in Japan and China combined have reached EUR 2.6 million in 2020. This generally translates to EUR 
0.3 million royalties based on the agreed royalty rates, of which EUR 0.1 million could be recorded as revenues in 
fiscal year 2020. After the balance sheet date, PAION and Mundipharma have agreed on an amendment of the royalty 
calculation. A corresponding contract amendment is currently being put in place based on which the remaining EUR 0.2 
million royalties will be recognized as revenues in fiscal year 2021. 
In the U.S., licensee Acacia Pharma launched BYFAVO(TM) (remimazolam) in January 2021 and has recently reported that 
the launch is proceeding extremely well. 
Preliminary 2020 Financial Results: 
The preliminary (unaudited) consolidated figures for fiscal year 2020 (IFRS) are in line with the forecast: 
According to preliminary figures, revenues increased to EUR 19.7 million in fiscal year 2020, compared to EUR 8 million 
in the previous year, and resulted primarily from milestone payments in connection with the market approvals of 
remimazolam in the U.S., Japan and China, as well as the license extension for remimazolam signed with Hana Pharm in 
January 2020 to include six additional countries in Southeast Asia. 
Research and development expenses amounted to EUR 10.3 million (prior-year period: EUR 13.1 million) and mainly relate 
to the EU Phase III study in general anesthesia. 
Primarily in the context of establishing a supply chain and preparing for the commercialization of remimazolam, general 
administrative and selling expenses increased by EUR 2.5 million year-on-year to EUR 7.5 million in the reporting 
period. 
Net income in fiscal year 2020 amounted to EUR 2.2 million compared to a net loss of EUR 7 million in the previous 
year. 
The preliminary consolidated annual figures are thus in line with the forecast. PAION AG plans to publish the annual 
financial report for fiscal year 2020 on 30 March 2021 after 5 pm CEST. 
"The year 2020 marked a turning point for PAION, with outstanding milestones such as the first approvals of remimazolam 
in the major pharmaceutical markets U.S., Japan and China, and followed by successful launches by our partners," 
commented Dr. Jim Phillips, CEO of PAION AG. "Our recent in-licensing of the critical care products GIAPREZA^(R) and 
XERAVA^(R) confirmed our decision to build our own infrastructure for the commercialization of our product portfolio in 
selected European countries. With the soon anticipated European approval of remimazolam in procedural sedation, we look 
forward to commercialize a third product in Europe. The launches of these three products in other major pharma markets 
have been proceeding well, and we therefore expect similar strong interest from hospitals in Europe to utilize these 
novel products addressing important unmet medical needs." 
Abdelghani Omari, CFO of PAION AG, added: "The gross proceeds from the capital increase and the third tranche from the 
EIB loan of about EUR 15.3 million in total together with cash at hand secure a liquidity runway into the first half of 
2022 based on current plans." 
### 
About PAION 
PAION AG is a publicly listed specialty pharmaceutical company focused on developing and commercializing innovative 
drugs for out-patient and hospital-based sedation, anesthesia and critical care services. PAION's lead compound is 
remimazolam, an intravenous, ultra-short-acting and controllable benzodiazepine sedative/anesthetic. Remimazolam is 
partnered in multiple territories outside of Europe. Remimazolam is approved in the U.S. and China for procedural 
sedation and in Japan and South Korea for general anesthesia. 
In Europe, PAION is seeking approval of Byfavo^(R) (remimazolam) for general anesthesia and for procedural sedation. In 
January 2021, the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) recommended 
approval of Byfavo^(R) in procedural sedation. It is planned to commercialize Byfavo^(R) once approved in Europe 
together with GIAPREZA^(R), a vasoconstrictor indicated for the treatment of refractory hypotension in adults with 
septic or other distributive shock who remain hypotensive despite adequate volume restitution and application of 
catecholamines and other available vasopressor therapies, and XERAVA^(R) for the treatment of complicated 
intra-abdominal infections in adults. 
PAION's mission is to be a leading specialty pharmaceutical company in the fields of anesthesia and critical care by 
bringing novel products to market to benefit patients, doctors and other stakeholders in healthcare. 
PAION is headquartered in Aachen (Germany) with an additional site in Cambridge (United Kingdom). 
Contact 
Ralf Penner 
Vice President Investor Relations/Public Relations 
PAION AG 
Heussstraße 25 
52078 Aachen - Germany 
Phone [phone] 
E-mail [e-mail] 
www.paion.com 
Disclaimer: 
This release contains certain forward-looking statements concerning the future business of PAION AG. These 
forward-looking statements contained herein are based on the current expectations, estimates and projections of PAION 
AG's management as of the date of this release. They are subject to a number of assumptions and involve known and 
unknown risks, uncertainties and other factors. Should actual conditions differ from the Company's assumptions, actual 
results and actions may differ materially from any future results and developments expressed or implied by such 
forward-looking statements. Considering the risks, uncertainties and other factors involved, recipients should not rely 
unreasonably upon these forward-looking statements. PAION AG has no obligation to periodically update any such 
forward-looking statements to reflect future events or developments. 
This release does not constitute an offer of securities for sale or a solicitation of an offer to purchase securities 
of PAION AG in the United States or any other jurisdiction. Neither this announcement nor anything contained herein 
shall form the basis of, or be relied upon in connection with, any offer or commitment whatsoever in any jurisdiction. 
The securities of PAION AG may not be offered or sold in the United States absent registration or an exemption from 
registration under the U.S. Securities Act of 1933, as amended (the "Securities Act"). The securities of PAION AG have 
not been, and will not be, registered under the Securities Act. 
=---------------------------------------------------------------------------------------------------------------------- 
2021-03-19 Dissemination of a Corporate News, transmitted by DGAP - a service of EQS Group AG. 
The issuer is solely responsible for the content of this announcement. 
The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. 
Archive at www.dgap.de 
=---------------------------------------------------------------------------------------------------------------------- 
Language:     English 
Company:      PAION AG 
              Heussstraße 25 
              52078 Aachen 
              Germany 
Phone:        [phone] 
Fax:          [phone] 
E-mail:       [e-mail] 
Internet:     www.paion.com 
ISIN:         DE000A0B65S3 
WKN:          A0B65S 
Listed:       Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, 
              Hamburg, Munich, Stuttgart, Tradegate Exchange 

(MORE TO FOLLOW) Dow Jones Newswires

March 19, 2021 15:18 ET (19:18 GMT)