Certain Warrants of PLx Pharma Inc. are subject to a Lock-Up Agreement Ending on 2-JUN-2021. These Warrants will be under lockup for 91 days starting from 3-MAR-2021 to 2-JUN-2021. Details: The officers and directors, have agreed to a 90-day “lock-up” with respect to shares of common stock and other of securities that they beneficially own, including securities that are convertible into shares of common stock and securities that are exchangeable or exercisable for shares of common stock. This means that, subject to certain exceptions, for a period of 90 calendar days following the date of this prospectus supplement, such persons may not offer, sell, pledge or otherwise dispose of these securities without the prior written consent of Raymond James.