The departures include that of Dimitri Panayotopoulos, an adviser to Lafley, who in a 36-year career at P&G held management jobs overseas. He is stepping down on January 2.

CTO Bruce Brown will leave on February 1 and will be replaced by Kathleen Fish, who currently oversees research and development in P&G's fabric business.

"These changes demonstrate the depth and strength of P&G's leadership bench," said Lafley, a former CEO who returned to the helm in May to replace Bob McDonald.

Robert Fregolle, global customer business development officer, will leave in June and be replaced by Carolyn Tastad, currently a vice president.

(Reporting by Phil Wahba in New York; Editing by Maureen Bavdek)