Certain Warrants of Prometheus Biosciences, Inc. are subject to a Lock-Up Agreement Ending on 8-SEP-2021. These Warrants will be under lockup for 181 days starting from 11-MAR-2021 to 8-SEP-2021. Details: The executive officers, directors, and all of the holders of equity securities have entered into a lock up agreement pursuant to which, they will not to directly or indirectly offer, pledge, sell or contract to sell any common stock, sell any option or contract to purchase any common stock, purchase any option or contract to sell any common stock, grant any option, right or warrant for the sale of any common stock, otherwise dispose of or transfer any common stock, request or demand that file a registration statement related to the common stock or enter into any swap or other agreement or any transaction that transfers, in whole or in part, the economic consequence of ownership of any common stock, whether any such swap, agreement or transaction is to be settled by delivery of shares or other securities, in cash or otherwise transfer any common stock or securities convertible into or exchangeable or exercisable for common stock, for a period of 180 days after the date of the final prospectus, without the prior written consent of SVB Leerink LLC and Credit Suisse Securities (USA) LLC, on behalf of the underwriters.