Certain Options of Protagonist Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 16-AUG-2021. These Options will be under lockup for 61 days starting from 16-JUN-2021 to 16-AUG-2021.

Details:
The executive officers, and directors have agreed, subject to specified exceptions, not to directly or indirectly to sell, offer, contract or grant any option to sell (including any short sale), pledge, transfer, establish an open “put equivalent position” within the meaning of Rule 16a-l(h) under the Securities Exchange Act of 1934, as amended, or otherwise dispose of any shares of common stock, options or warrants to acquire shares of common stock, or securities exchangeable or exercisable for or convertible into shares of common stock currently or hereafter owned either of record or beneficially, or publicly announce an intention to do any of the foregoing for a period of 60 days after the date of this prospectus supplement without the prior written consent of J.P. Morgan Securities LLC.