SOUTH PLAINFIELD, N.J. - PTC Therapeutics, Inc. (NASDAQ: PTCT) announced that the company will present three posters outlining data for EMFLAZA (deflazacort) in Duchenne muscular dystrophy (DMD) at the Muscular Dystrophy Association (MDA) Clinical & Scientific Conference being held March 13-16 in Nashville, Tenn. and virtually.

For the first time, PTC will be presenting data on the association between steroid treatment and clinical outcomes among non-ambulatory patients with DMD, expanding the body of evidence that supports the potential cumulative benefit of deflazacort versus prednisone in this patient population. These results have not been previously published and further advance the clinical understanding of steroid treatment in the continuum of DMD care.

Poster presentations include:

Poster Title: Associations Between Deflazacort vs Prednisone/prednisolone and Disease Progression Markers in Subgroups of Patients with Duchenne Muscular Dystrophy

Poster Number: 109

Poster Title: Associations Between Daily Deflazacort or Prednisone and Ages at Disease Progression Milestones Among Patients with Duchenne Muscular Dystrophy

Poster Number: 110

Poster Title: Associations Between Steroid Treatment and Clinical Outcomes Among Non-Ambulatory Patients with Duchenne Muscular Dystrophy

Poster Number: 95

Posters will be viewable in-person throughout the conference. All abstracts are available on the MDA Conference website at https://mdaconference.org/abstract-search.

PTC also will host a hybrid industry forum, 'Throughout the Disease Continuum: Corticosteroid Treatment in Duchenne Muscular Dystrophy,' on Tuesday, March 15 from 12:00-1:25 p.m. CDT. Those interested in attending in person or virtually can register at http://www.PTCIF2022.com. Participation is limited to licensed U.S. healthcare practitioners only.

About PTC Therapeutics, Inc.

PTC is a science-driven, global biopharmaceutical company focused on the discovery, development and commercialization of clinically differentiated medicines that provide benefits to patients with rare disorders. PTC's ability to innovate to identify new therapies and to globally commercialize products is the foundation that drives investment in a robust and diversified pipeline of transformative medicines. PTC's mission is to provide access to best-in-class treatments for patients who have little to no treatment options. PTC's strategy is to leverage its strong scientific and clinical expertise and global commercial infrastructure to bring therapies to patients. PTC believes this allows it to maximize value for all its stakeholders. To learn more about PTC, please visit us at www.ptcbio.com and follow us on Instagram, Facebook, Twitter, and LinkedIn.

Contact:

Investors

Kylie O'Keefe

T: +1 (908) 300-0691

E: kokeefe@ptcbio.com

Media

Jeanine Clemente

T: +1 (908) 912-9406

E: jclemente@ptcbio.com

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this release, other than statements of historic fact, are forward-looking statements, including statements regarding: the future expectations, plans and prospects for PTC, including with respect to the commercialization of its products and product candidates; PTC's strategy, future operations, future financial position, future revenues, projected costs; and the objectives of management. Other forward-looking statements may be identified by the words 'guidance', 'plan,' 'anticipate,' 'believe,' 'estimate,' 'expect,' 'intend,' 'may,' 'target,' 'potential,' 'will,' 'would,' 'could,' 'should,' 'continue,' and similar expressions.

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As with any pharmaceutical under development, there are significant risks in the development, regulatory approval, and commercialization of new products. There are no guarantees that any product will receive or maintain regulatory approval in any territory or prove to be commercially successful, including Emflaza.

The forward-looking statements contained herein represent PTC's views only as of the date of this press release and PTC does not undertake or plan to update or revise any such forward-looking statements to reflect actual results or changes in plans, prospects, assumptions, estimates or projections, or other circumstances occurring after the date of this press release except as required by law.

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