On July 8, 2021, Allison Dorval, 45, was appointed to the Board of Directors (the Board") of Puma Biotechnology, Inc., effective July 15, 2021. Ms. Dorval will serve on the Board for a term expiring at the 2022 Annual Meeting of Stockholders and until her successor is duly elected and qualified, or until her earlier death, resignation or removal. In connection with her appointment to the Board, Ms. Dorval was also appointed to the Audit Committee of the Board (the Audit Committee"). Ms. Dorval has served as the Chief Financial Officer of Voyager Therapeutics, Inc., since November 2018 and as Voyager's principal financial officer and principal accounting officer since June 2018.