Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On December 31, 2020, Sung Lee, Executive Vice President, Chief Financial Officer and Principal Financial Officer of Sangamo Therapeutics, Inc. (the "Company"), notified the Company of his resignation from these positions and from his employment with the Company, in each case to be effective on February 1, 2021, in order to pursue a new opportunity overseas. Mr. Lee's resignation is not due to any disagreement with the Company on any matter relating to the Company's operations, financial statements, internal controls, auditors, policies or practices.

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