Item 7.01 Regulation FD Disclosure

On February 6, 2023, Dr. Anatoly Dritschilo, the CEO of Shuttle Pharmaceuticals Holdings, Inc., a Delaware corporation (the "Company"), participated in a video interview with Proactive Investors, an international financial media company. The interview will be available for replay at the Proactive Investors website, as well as YouTube, using the following link:

https://youtu.be/K-QFWPG2OoU

By filing this Current Report on Form 8-K and furnishing the information contained herein, the Company makes no admission as to the materiality of any information in this report that is required to be disclosed solely by reason of Regulation FD. The Company uses, and will continue to use, its website, press releases, and, from time to time, various social media channels such as YouTube as additional means of disclosing public information to investors, the media and others interested in the Company. It is possible that certain information that the Company posts on its website, disseminates in press releases and on social media could be deemed to be material information, and the Company encourages investors, the media and others interested in the Company to review the business and financial information that the Company posts on its website, disseminates in press releases and on the social media channels identified above, as such information could be deemed to be material information.

The information in this Item 7.01 is being furnished and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities under that Section. In addition, the information in this Item 7.01 disclosure shall not be incorporated by reference into the filings of the Company under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

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