The Board of Directors of Sino Biopharmaceutical Limited (the Company, together with its subsidiaries, the Group) announces that Lenvatinib Mesilate Capsule, a liver cancer treatment drug developed by the Group, has obtained drug registration certificate granted by the National Medical Products Administration of the PRC. This product was filed as a Chemicals Category 4 drug, and is deemed to have passed the Consistency of Quality and Efficacy Evaluation for Generic Drugs, being the first generic drug of its kind that has obtained approval for drug registration in China. The approved indication is: for the treatment of unresectable hepatocellular carcinoma patients who have not received systemic treatment in the past. Lenvatinib is a multiple tyrosine kinase receptors (RTK) inhibitor, which can inhibit the kinase activity of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR) and VEGFR3 (FLT4), and also inhibit fibroblast growth factor receptors (FGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor KIT and RET fusion genes, thereby inhibiting tumor angiogenesis and tumor progression. Lenvatinib mesilate was the only drug that had obtained positive results in phase III clinical studies in the field of first-line targeted therapy for liver cancer in the past decade. Clinical data showed that the efficacy of lenvatinib mesilate was particularly impressive in the Chinese patient subgroup compared to the total global population. Lenvatinib mesilate has been adopted as the first-line drug for the treatment of middle-late stage liver cancer in countries including China, Japan, and the United States. According to statistics, there are 466,000 new liver cancer patients in China each year, accounting for more than half of the global incidence (cited from: Cancer Statistics in China, 2015). Currently, only the brand-name drug of lenvatinib mesilate capsule is available in the domestic market, so there is a wide market potential. The approval for the launch of lenvatinib mesilate capsule developed by the Group will further improve the Group's anti-tumor product line layout and help reduce the economic burden of liver cancer patients in China.