Valuation: Sionna Therapeutics, Inc.

Capitalization 2.04B 1.73B 1.6B 1.5B 2.79B 189B 2.84B 18.71B 7.33B 91.13B 7.64B 7.48B 324B P/E ratio 2026 *
-19.9x
P/E ratio 2027 * -18.6x
Enterprise value 1.96B 1.66B 1.54B 1.45B 2.69B 182B 2.73B 18.01B 7.06B 87.74B 7.35B 7.2B 312B EV / Sales 2026 *
-
EV / Sales 2027 * 530x
Free-Float
94.89%
Yield 2026 *
-
Yield 2027 * -
1 day+0.33%
1 week+16.33%
Current month+12.85%
1 month+21.71%
3 months+15.67%
6 months+38.26%
Current year+9.97%
1 week 36.91
Extreme 36.91
46.1
1 month 33.2
Extreme 33.2
46.1
Current year 32.46
Extreme 32.46
46.1
1 year 10.07
Extreme 10.07
46.1
3 years 7.26
Extreme 7.255
46.1
5 years 7.26
Extreme 7.255
46.1
10 years 7.26
Extreme 7.255
46.1
Manager TitleAgeSince
Corporate Officer/Principal - 2019-07-31
Corporate Officer/Principal - 2019-07-31
Chief Executive Officer 54 2021-04-30
Director TitleAgeSince
Director/Board Member 51 2019-11-30
Director/Board Member 44 2019-11-30
Director/Board Member 51 2020-05-31
Change 5d. change 1-year change 3-years change Capi.($)
+0.33%+16.33%+352.40% - 2.04B
-0.41%+5.02%-1.85%-9.41% 47.35B
+0.24%+2.32%+40.57%+21.48% 35.57B
-2.14%+55.13%+312.35%+574.21% 31.16B
-3.45%+1.76%+15.84%-14.18% 28.86B
+3.47%+3.72%+36.62%+29.82% 29.62B
+0.51%+0.51%+53.62%+199.31% 15.01B
-0.56%+2.82%+73.91%+168.37% 14.73B
+2.55%+8.52%+4,163.00%+4,049.02% 15.12B
-0.29%+8.19%+37.00%+11.64% 14.34B
Average +0.03%+10.67%+508.35%+558.92% 23.38B
Weighted average by Cap. -0.17%+11.11%+336.63%+369.05%

Financials

2026 *2027 *
Net sales - 3.75M 3.18M 2.94M 2.77M 5.14M 349M 5.23M 34.46M 13.51M 168M 14.07M 13.77M 597M
Net income -108M -91.96M -84.91M -80.05M -148M -10.08B -151M -995M -390M -4.85B -406M -398M -17.24B -125M -106M -98.13M -92.52M -172M -11.65B -175M -1.15B -451M -5.6B -470M -460M -19.92B
Net Debt -75.62M -64.22M -59.29M -55.9M -104M -7.04B -105M -695M -272M -3.39B -284M -278M -12.04B -48.87M -41.5M -38.32M -36.12M -67.01M -4.55B -68.18M -449M -176M -2.19B -183M -180M -7.78B
Logo Sionna Therapeutics, Inc.
Sionna Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on researching and developing novel medicines for cystic fibrosis. It is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). It is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. It is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.
Employees
59
Date Price Change Volume
26-04-16 45.24 $ +0.33% 817,608
26-04-15 45.09 $ +4.13% 768,535
26-04-14 43.30 $ +3.66% 900,098
26-04-13 41.77 $ +10.24% 382,801
26-04-10 37.89 $ -2.57% 223,104
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
10
Last Close Price
45.24USD
Average target price
49.11USD
Spread / Average Target
+8.56%

Quarterly revenue - Rate of surprise