Takeda Pharmaceutical Company Limited announced that it will redeem $1,000,000,000 of the total $1,500,000,000 outstanding aggregate principal amount of the Notes on October 27, 2022 at the Redemption Price calculated in the manner set below. The Notes were issued pursuant to an indenture dated as of November 26, 2018, by and between the Company and U.S. Bank National Association, as successor trustee to MUFG Union Bank, N.A., as trustee. Capitalized terms used and not otherwise defined herein have the meanings given thereto in the Indenture.

This redemption is being made at the option of the Company pursuant to Section 10.1 of the Indenture. This notice of redemption is being given pursuant to Sections 1.6 and 10.5 of the Indenture in accordance with the terms of the Notes.