ACTIVATING THE
PATIENT'S IMMUNE SYSTEM
TO FIGHT CANCER
1H & 2Q 2022 presentation
18 August 2022
OSE:
TRVX
IMPORTANT NOTICE AND DISCLAIMER
This report contains certain forward-looking statements based on uncertainty, since they relate to events and depend on circumstances that will occur in future and which, by their nature, will have an impact on the results of operations and the financial condition of Targovax. Such forward-looking statements reflect the current views of Targovax and are based on the information currently available to the company. Targovax cannot give any assurance as to the correctness of such statements.
There are a number of factors that could cause actual results and developments to differ materially from those expressed or implied in these forward-looking statements. These factors include, among other things, risks or uncertainties associated with the success of future clinical trials; risks relating to personal injury or death in connection with clinical trials or following commercialization of the company's products, and liability in connection therewith; risks
relating to the company's freedom to operate (competitors patents) in respect of the products it develops; risks of non- approval of patents not yet granted and the company's ability to adequately protect its intellectual property and know- how; risks relating to obtaining regulatory approval and other regulatory risks relating to the development and future commercialization of the company's products; risks that research and development will not yield new products that achieve commercial success; risks relating to the company's ability to successfully commercialize and gain market acceptance for Targovax' products; risks relating to the future development of the pricing environment and/or regulations for pharmaceutical products; risks relating to the company's ability to secure additional financing in the
future, which may not be available on favorable terms or at all; risks relating to currency fluctuations; risks associated with technological development, growth management, general economic and business conditions; risks relating to the company's ability to retain key personnel; and risks relating to the impact of competition.
2
IMPORTANT PROGRESS WAS MADE ON ALL THREE
STRATEGIC PILLARS DURING 1H 2022
✓ Secured partnership to access free supply of | |
ONCOS-102 | checkpoint inhibitors to melanoma phase 2 trial |
✓ FDA filing in time with ongoing follow-up, | |
phase 2 trial go-ahead expected in 3Q´22 |
Mutant
KRAS
✓
✓
✓
External funding and partnerships secured
Enhanced TG01 potency with QS-21 adjuvant
US IND approved for TG01 / QS-21
Circular
RNA
- Research operations established at Karolinska Institutet in Stockholm
- Key hires executed and growing the team
- Compelling early data already emerging
3
2Q OPEX IN LINE WITH PREVIOUS QUARTERS
NOK m | ||
Total revenue | ||
R&D expenses | 1 | |
Payroll and related expenses | ||
Other operating expenses | 2 | |
Total operating expenses | ||
Operating loss | ||
Net financial items | ||
Loss before income tax | ||
Net change in cash | ||
Net cash EOP |
2Q21 | 3Q21 | 4Q21 | 1Q22 | 2Q22 |
0 | 0 | 0 | 0 | 0 |
- | ||||
-9 | -10 | -10 | -9 | -14 |
-13 | -11 | -13 | -16 | -14 |
-3 | -2 | -2 | -3 | -3 |
-25 | -23 | -26 | -29 | -31 |
-25 | -23 | -26 | -29 | -31 |
-1 | -1 | -1 | -1 | 2 |
-26 | -23 | -27 | -30 | -29 |
-24 | -17 | 128 | -32 | -24 |
71 | 54 | 182 | 150 | 126 |
4
1 Including patent cost
2 Including depreciation
2Q FINANCIAL SNAPSHOT
Key figures
Net cash flow in 2Q
- 24 | - 2.4 |
NOK million | USD million |
Cash at end of 2Q
126 | 12.6 |
NOK million | USD million |
Market cap | |
300 | 30 |
NOK million | USD million |
Daily value traded
Average last 12 months
2.5 | 0.25 |
NOK million | USD million |
Shareholder base
Estimated ownership1 | ||
Shareholder | Shares million | Ownership |
HealthCap | 12.4 | 6.6 % |
Avanza Bank AB (nom.) | 8.9 | 4.7 % |
Goldman Sachs Int. (nom.) | 5.2 | 2.8 % |
Nordnet Bank AB (nom.) | 4.9 | 2.6 % |
Bækkelaget Holding AS | 4.6 | 2.4 % |
RadForsk | 4.4 | 2.3 % |
Nordea | 4.0 | 2.1 % |
Høse AS | 3.1 | 1.6 % |
Nordnet Livsforsikring | 2.6 | 1.4 % |
Andreassen, Jon-Arild | 2.3 | 1.2 % |
10 largest shareholders | 52.6 | 27.9 % |
Other shareholders (6 724) | 135.9 | 72.1 % |
Total shareholders | 188.5 | 100.0 % |
1 As per 4 August 2022
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Targovax ASA published this content on 18 August 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 18 August 2022 05:13:01 UTC.