The Estee Lauder Companies (ELC) Research & Development (R&D) teams continue to lead in skin research and are committed to better understanding the physical and biological processes that cause skin aging to drive the next breakthrough product innovations. Scientists from the Estee Lauder, Clinique and Origins brand laboratories recently shared their latest innovative findings in skin research at the 45th Annual Meeting of the Japanese Society for Investigative Dermatology (JSID) conference.

This prestigious conference is held annually to advance the position of dermatology in the interdisciplinary world and to enhance the quality of science and research presentations in dermatology for the purpose of maintaining healthy skin. The JSID was held virtually for the first time this year.

Dr. Jaime Emmetsberger, Associate Fellow R&D Research Sciences, ELC, and Dr. Tom Mammone, Vice President, Skin Physiology and Pharmacology, R&D, ELC, presented innovative data focused on the connection between the contraction of facial muscles and skin aging. The results of this study from Clinique Laboratories will increase understanding muscle contraction physiology, allowing researchers to better investigate the effect that those contractions have on the skin, including on the appearance of dynamic wrinkles.

The Estee Lauder brand revealed new findings across topics such as miRNAs, sirtuin activity, cellular shape and autophagy linked to inflammation and pigmentation, which leverage years of research to expand the brand's leadership in epigenetics and mechanobiology. Dr. Nadine Pernodet, Vice President, Skin Biology and BioActives, R&D, ELC was also selected to give an oral presentation titled, The Importance of Sirtuins in Skin and New Findings about Sirt-2 and its Link to Mechanobiology. Additionally, Estee Lauder hosted a symposium exploring the relationship between circadian clocks and microRNAs and their roles in skin aging.

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Dr. Nadine Pernodet, Vice President, Skin Biology and BioActives, Research & Development

Dr. Rocky Graziose, Associate Director R&D Research Sciences

Dr. Jaime Emmetsberger, Associate Fellow R&D Research Sciences

Dr. Tom Mammone, Vice President, Skin Physiology and Pharmacology, Research & Development

Dr. Nadine Pernodet, Vice President, Skin Biology and BioActives, Research & Development

Dr. Rocky Graziose, Associate Director R&D Research Sciences

Dr. Jaime Emmetsberger, Associate Fellow R&D Research Sciences

Dr. Tom Mammone, Vice President, Skin Physiology and Pharmacology, Research & Development

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Dr. Rocky Graziose, Associate Director R&D Research Sciences, ELC, revealed a new study demonstrating that topical application of a formulation with mushroom extract helps prevent the over-accumulation of inflammation-triggering cells within the skin, a major cause of skin aging. Building upon over a decade of study on mushrooms, these findings from Origins Laboratories also demonstrated that the fermented mushroom showed increased activity in balancing skin self-protecting mechanisms.

'As a brand-led innovation company, ELC continues to enable our brands to benefit from the latest scientific breakthroughs and deliver transformative products, especially now as the demand for skin care remains strong,' said Carl Haney, Executive Vice President, Research, Product and Innovation Officer at ELC. 'Our exceptional talent across our brands remain committed to meeting that demand and developing locally relevant products through our industry-leading research and creativity-driven innovation.'

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