Thermo Fisher Scientific Inc. unveiled the Gibco? CTS? Detachable Dynabeads?

CD4 and CTS Detachable Dynabeads CD8 (CTS Detachable Dynabeads). These latest products expand on Thermo Fisher's CTS Detachable Dynaboods platform, which represents a new generation of cell therapy isolation and/or activation products that prioritize cell quality while also creating greater workflow control. Ultimately, these products can help customers maximize the potential of their therapies to save more lives.

Studies have shown that a balance of CD4+ and CD8+ Chimeric Antigen Receptor (CARs) seem most effective for CAR-T cell therapy. The specific binding properties of the new CTS Detachable DynabADs CD4 and CTS Detaching Dynabeads CD8 products enable efficient isolation of CD4+ and CD 8+ T cells, minimize cell stress and ensure high purity and yield of the desired cell populations. When used together with the CTS Detachable Dynaboes Release buffer, these products empower users with a first-of-its-kind cGMP cell selection technology that has an active release mechanism for process development, clinical trial and commercial manufacturing uses.

As a result, users can achieve more process flexibility and gain greater control over cell purity, yield and phenotype, which can help cell therapy developers bring life-changing treatments to patients faster, especially for those diagnosed with complex diseases such as blood cancers. The CTS Detachable Dynabods platform works within Thermo Fisher Scientific's modular, closed and automated cell therapy manufacturing workflow. In combination with Thermo Fisher Scientific's Gibco Cell Therapy Systems (CTS) portfolio of products, including the Gibco CTS DynaCellect?

Magnetic Separation System, CTS Detachable Dynabads allow users to shorten their manufacturing workflow by decreasing the time for steps downstream of cell isolation. Thermo Fisher's CTS portfolio of products are manufactured according to cGMP, designed to meet applicable cell therapy standards, and include traceability and regulatory documentation to help customers transition from research to clinical trials and commercial production.