Thermo Fisher Scientific is showcasing its new software solutions during the 69th American Society for Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Allied Topics, being held October 31-November 4, in the Pennsylvania Convention Center, Philadelphia, Pennsylvania. Deep learning tools to transform proteomics data analysis: The newest Thermo Scientific Proteome Discoverer 3.0 software combines with the CHIMERYS search engine by MSAID to allow Thermo Scientific Orbitrap mass spectrometer users to more fully interpret the data generated by their instruments. Artificial intelligence (AI) enables a deeper mining of proteomics data, which substantially increases the identification of unique peptides and improves overall protein coverage. Proteome Discoverer 3.0 software also includes an updated INFERYS prediction model, the Comet search engine, and a SureQuant method exporter node. The deep learning technology is a breakthrough, allowing researchers to go beyond standard search engines and unlock new possibilities in the proteomics field. New peak detection and filtering improves and accelerates untargeted small molecule workflows: Small molecule researchers can now benefit from Thermo Scientific Compound Discoverer 3.3?software to detect more compounds in less time, faster and more sensitive peak detection. The new software provides peak quality reporting to help determine and filter relevant compounds, streamlining the data review process. Scientists can improve confidence in compound annotations through MSn spectral tree search capabilities in tandem with the Thermo Scientific mzCloud spectral library to address the most challenging unknown compounds. Compound Discoverer 3.3 software, which has been optimized for processing large datasets and detecting low-abundance compounds, will support scientists in metabolomics, pharmaceutical, environmental, food safety, clinical and forensics applications to acquire the results they need to drive science forward. Simplify comprehensive biotherapeutic attribute characterization workflows: Apply advanced new capabilities for biotherapeutic workflows with Thermo Scientific BioPharma Finder 5.0 software to speed time to results. Increase throughput and confidence with built-for-purpose data processing, curation, and customizable reporting in a secure connected environment to streamline and enable collaboration on a global scale. Scientists can leverage BioPharma Finder software across multiple application workflows and modalities including peptide mapping analysis, oligonucleotide analysis, intact mass analysis and top down analysis for increased confidence and productivity. Direct infusion workflows now supported for lipid-profiling software: Thermo Scientific LipidSearch 5.0 software?is now compatible with direct-infusion mass spectrometry to deliver real-time monitoring coupled with accurate lipid identification. The peak detection engine included in the software provides accurate peak detection with a new and improved graphical user interface. LipidSearch 5.0 software also features a new retention time correction algorithm for liquid chromatography workflows, providing even more accurate quantitation, and includes a customizable lipid database containing over 1.5 million lipids and their predicted fragment ions.