Item 8.01. Other Events.

On February 23, 2021, Ventas, Inc. (the "Company") filed with the Securities and Exchange Commission (the "SEC") a Registration Statement on Form S-3 (File No. 333-253415) (the "Replacement Registration Statement"), which became effective automatically upon filing. The Replacement Registration Statement replaces the Company's Registration Statement on Form S-3 (File No. 333-222998), which expired on February 13, 2021. In connection with the filing of the Replacement Registration Statement, the Company was required to file a new prospectus supplement for its existing "at the market" equity offering program. This prospectus supplement, which reflects the amendment of the Sales Agreement described below, was filed on February 23, 2021.

Also on February 23, 2021, the Company entered into Amendment No. 1 (the "Amendment No. 1") to the ATM Equity OfferingSM Sales Agreement, dated July 31, 2018 (as may be amended from time to time, the "Sales Agreement"), with BofA Securities, Inc., Citigroup Global Markets Inc., Credit Agricole Securities (USA) Inc., Jefferies LLC, J.P. Morgan Securities LLC, Mizuho Securities USA LLC, Morgan Stanley & Co. LLC, MUFG Securities Americas Inc., RBC Capital Markets, LLC, Scotia Capital (USA) Inc., SMBC Nikko Securities America, Inc., TD Securities (USA) LLC, UBS Securities LLC and Wells Fargo Securities, LLC (collectively, the "Sales Agents"). The purpose of Amendment No. 1 was to add additional Sales Agents as parties to the Sales Agreement. Under the Sales Agreement, an aggregate gross price of $244,540,822 of the Company's common stock has been offered and sold through February 23, 2021. As a result of such prior sales, as of February 23, 2021, shares of the Company's common stock having an aggregate gross sales price of up to $755,459,178 remain available for future issuance under the Sales Agreement.

A copy of Amendment No. 1 is filed herewith as Exhibit 1.1 and is incorporated by reference herein. An opinion of Latham & Watkins LLP with respect to the validity of shares of the Company's common stock that may be offered and sold pursuant to this prospectus supplement and the accompanying prospectus is filed herewith as Exhibit 5.1. This Current Report on Form 8-K shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.




Item 9.01.     Financial Statements and Exhibits.



(d) Exhibits:



Exhibit

 Number    Description
  1.1        Amendment No. 1 to ATM Equity OfferingSM Sales Agreement, dated
           February 23, 2021, among the Company, BofA Securities, Inc., Citigroup
           Global Markets Inc., Credit Agricole Securities (USA) Inc., Jefferies
           LLC, J.P. Morgan Securities LLC, Mizuho Securities USA LLC, Morgan
           Stanley & Co. LLC, MUFG Securities Americas Inc., RBC Capital Markets,
           LLC, Scotia Capital (USA) Inc., SMBC Nikko Securities America, Inc., TD
           Securities (USA) LLC, UBS Securities LLC and Wells Fargo Securities,
           LLC.
  5.1        Opinion of Latham & Watkins LLP.
  23.1       Consent of Latham & Watkins LLP (included in Exhibit 5.1).
  104      Cover Page Interactive Data File (formatted as inline XBRL).

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