Item 8.01 Other Events.

On November 4, 2021, VYNE Therapeutics Inc. issued a press release entitled "Lead BET Inhibitor, VYN201, Demonstrates Improvement in Reducing Fibrotic Tissue Mass and Overall Skin Repair Outcomes in Preclinical Study." A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference herein.

Item 9.01. Financial Statements and Exhibits.





(d) Exhibits


The following exhibit is being filed herewith.




Exhibit No.         Description

  99.1                Press Release, dated November 4, 2021.

104                 Cover Page Interactive Data File (embedded within the Inline XBRL document)

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