Item 8.01 Other Events.

On March 7, 2022, VYNE Therapeutics Inc. issued a press release entitled "VYNE Reports Positive Preclinical Data for Lead BET Inhibitor, VYN201, in Human Skin Model of Vitiligo." A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference herein.

Item 9.01. Financial Statements and Exhibits.





(d) Exhibits

The following exhibit is being filed herewith.





Exhibit No.              Description

  99.1                     Press Release, dated March 7, 2022.

                         Cover Page Interactive Data File (embedded within the
104                      Inline XBRL document)

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