Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement.

WUXI APPTEC CO., LTD.*

無錫藥明康德新藥開發股份有限公司

(A joint stock company incorporated in the People's Republic of China with limited liability)

(Stock Code: 2359)

END OF LOCK-UP PERIOD OF RESTRICTED A SHARES

UNDER THE A SHARE IPO

  1. Introduction
    Pursuant to the Approval of China Securities Regulatory Commission regarding the Initial Public Offering of Shares of WuXi AppTec Co., Ltd. (關於核准無錫藥 明康德新藥開發股份有限公司首次公開發行股票的批覆) (Zheng Jian Xu Ke [2018] No. 678), WuXi AppTec Co., Ltd.* (無錫藥明康德新藥開發股份有限公 司) (the "Company") issued 104,198,556 Renminbi-denominated ordinary shares (the "A Shares") to the public on April 13, 2018, which were listed on Shanghai Stock Exchange on May 8, 2018 (the "A Share IPO"). With respect to the A Share IPO, certain shareholders of the Company have undertaken that within 36 months immediately following the listing date of the A Share IPO, they will not dispose of any A Shares held by them (the "Lock-upUndertakings"). Such A Shares (the "Restricted A Shares") shall be released from the selling restrictions under the Lock-up Undertakings and available for trading from May 10, 2021 (the "Lock-upRelease").
    There are 22 holders of A Shares of the Company which have provided the Lock-up Undertakings before the A Share IPO, namely G&C VI Limited ("G&C VI"), G&C V
    Limited ("G&C V"), Jiaxing Yuxiang Investment Partnership (Limited Partnership)* (嘉興宇祥投資合夥企業(有限合夥)) ("Jiaxing Yuxiang"), Jiaxing Yumin Investment Partnership (Limited Partnership)* (嘉興宇民投資合夥企業(有限合夥))
    ("Jiaxing Yumin"), G&C VII Limited ("G&C VII"), Shanghai Houshen Investment Center (Limited Partnership)* (上海厚燊投資中心(有限合夥)) ("Shanghai Houshen"), Shanghai Houyong Investment Center (Limited Partnership)* (上海厚雍 投資中心(有限合夥)) ("Shanghai Houyong"), Shanghai Houqin Investment Center (Limited Partnership)* (上海厚溱投資中心(有限合夥)) ("Shanghai Houqin"), Shanghai Houyuan Investment Center (Limited Partnership)* (上海厚轅投資中 心(有限合夥)) ("Shanghai Houyuan"), Shanghai Houyue Investment Center (Limited Partnership)* (上海厚玥投資中心(有限合夥)) ("Shanghai Houyue"),

- 1 -

Shanghai Houyao Investment Center (Limited Partnership)* (上海厚堯投資中心

(有限合夥)) ("Shanghai Houyao"), Shanghai Housong Investment Center (Limited Partnership)* (上海厚嵩投資中心(有限合夥)) ("Shanghai Housong"), Shanghai Houling Investment Center (Limited Partnership)* (上海厚菱投資中心(有限合夥))

("Shanghai Houling"), Jiaxing Houyi Investment Partnership (Limited Partnership)* (嘉興厚毅投資合夥企業(有限合夥)) ("Jiaxing Houyi"), Jiaxing Houyu Investment Partnership (Limited Partnership)* (嘉興厚毓投資合夥企業(有限合夥)) ("Jiaxing

Houyu"), Jiaxing Houzi Investment Partnership (Limited Partnership)* (嘉興厚諮投

資合夥企業(有限合夥)) ("Jiaxing Houzi"), Jiaxing Houjin Investment Partnership (Limited Partnership)* (嘉興厚錦投資合夥企業(有限合夥)) ("Jiaxing Houjin"),

G&C IV Hong Kong Limited ("G&C IV Hong Kong"), Fertile Harvest Investment Limited (沃茂投資有限公司*) ("Fertile Harvest"), Eastern Star Asia Investment Limited (東星亞洲投資有限公司*) ("Eastern Star"), L&C Investment Limited

("L&C Investment") and Shanghai Yingyi Investment Center (Limited Partnership)* (上海瀛翊投資中心(有限合夥)) ("Shanghai Yingyi").

  1. Information about the Restricted A Shares to be available for trading
    The number of Restricted A Shares to be released from the selling restrictions is 633,784,587, representing 25.8621% of the total issued share capital of the Company as at the date of this announcement. The Restricted A Shares will be available for trading from May 10, 2021. Details of the Restricted A Shares available for trading are as follows:

Unit: Share

Percentage of

total number

of Restricted

A Shares of

the total share

Number of

capital of the

Number of A

Number of

Restricted A

Company as at

Shares to be

remaining

Shares being

the date of this

available for

Restricted A

No. Shareholders

held

announcement

trading

Shares

1

G&C VI

158,760,000

6.4783%

158,760,000

0

2

G&C IV Hong Kong

116,099,424

4.7375%

116,099,424

0

3

G&C V

81,124,596

3.3104%

81,124,596

0

4

Jiaxing Yuxiang

72,562,140

2.9610%

72,562,140

0

5

G&C VII

42,012,600

1.7144%

42,012,600

0

6

Shanghai Houshen

38,112,690

1.5552%

38,112,690

0

7

Jiaxing Yumin

24,186,204

0.9869%

24,186,204

0

8

Jiaxing Houyi

9,142,812

0.3731%

9,142,812

0

- 2 -

Percentage of

total number

of Restricted

A Shares of

the total share

Number of

capital of the

Number of A

Number of

Restricted A

Company as at

Shares to be

remaining

Shares being

the date of this

available for

Restricted A

No. Shareholders

held

announcement

trading

Shares

9

Jiaxing Houyu

9,142,812

0.3731%

9,142,812

0

10

Jiaxing Houzi

1,658,160

0.0677%

1,658,160

0

11

Jiaxing Houjin

1,658,160

0.0677%

1,658,160

0

12

Shanghai Houyong

1,571,430

0.0641%

1,571,430

0

13

Shanghai Houqin

1,212,750

0.0495%

1,212,750

0

14

Shanghai Houyuan

1,181,880

0.0482%

1,181,880

0

15

Shanghai Houyue

1,178,940

0.0481%

1,178,940

0

16

Shanghai Houyao

1,149,540

0.0469%

1,149,540

0

17

Shanghai Housong

1,042,230

0.0425%

1,042,230

0

18

Shanghai Houling

737,940

0.0301%

737,940

0

19

Fertile Harvest

32,270,832

1.3168%

32,270,832

0

20

Eastern Star

10,226,247

0.4173%

10,226,247

0

21

L&C Investment

8,214,948

0.3352%

8,214,948

0

22

Shanghai Yingyi

20,538,252

0.8381%

20,538,252

0

Total

633,784,587

25.8621%

633,784,587

0

- 3 -

III. Change in share capital

Unit: Share

Before the

After the

Lock-up

Lock-up

Release (Note)

Change

Release

Shares in issue subject to selling restrictions (A Shares)

  1. Shares held by other domestic legal persons
  2. Shares held by domestic natural persons
  3. Shares held by foreign legal persons and natural persons

Total number of Shares in issue subject to selling restrictions

185,075,940

-185,075,940

0

24,849,276

0

24,849,276

448,708,647

-448,708,647

0

658,633,863

-633,784,587

24,849,276

Shares in issue not subject to selling restrictions (A Shares)

1,476,224,574

633,784,587

2,110,009,161

H shares of the Company

315,775,162

0

315,775,162

Total number of Shares

2,450,633,599

0

2,450,633,599

Note: The share capital of the Company before the Lock-up Release has taken into account the unlocking of 199,087 Restrict A Shares granted under the reserved grant of the Restricted A Shares and Stock Option Incentive Plan of 2018 adopted by the Company for the first unlocking period, which will commence trading on May 7, 2021. Please refer to the relevant announcement of the Company dated April 28, 2021 for further details.

By order of the Board

WuXi AppTec Co., Ltd.

Dr. Ge Li

Chairman

Hong Kong, April 29, 2021

As of the date of this announcement, the board of directors of the Company comprises Dr. Ge Li, Mr. Edward Hu, Dr. Steve Qing Yang, Mr. Zhaohui Zhang and Dr. Ning Zhao as executive directors, Mr. Xiaomeng Tong and Dr. Yibing Wu as non-executive directors and Dr. Jiangnan Cai, Ms. Yan Liu, Mr. Dai Feng, Dr. Hetong Lou and Mr. Xiaotong Zhang as independent non-executive directors.

*For identification purpose only

- 4 -

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WuXi AppTec Co. Ltd. published this content on 29 April 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 29 April 2021 13:51:00 UTC.